stage

Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration and apoptosis were assessed by Transwell migration assays and flow cytometric analysis, respectively. SPP1 is highly expressed in tumor tissues and TAMs isolated from patients with an advanced TNM stage, and also in PMA-treated THP-1 cells.

Expression system: E. coli
Length: 41-196, Partial
Activity: Not Tested

Expression system: E. coli
Length: 23-394, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 23-394, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 19-88, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 23-392, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 17-228, Full Length of Mature Protein
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 17-230, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 17-230, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 25-467, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1-118, Full Length
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 1-118, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 125-452, Full Length of Mature Protein
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 125-453, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 125-453, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-179, Full Length
Activity: Not Tested

Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF VEGF growth factor family. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF‑1), 152 (PlGF‑2), and 203 (PlGF‑3) amino acids (aa) respectively. PlGF is mainly found as a variably glycosylated, secreted, 55 ‑ 60 kDa disulfide linked homodimer.The protein is a member of the VEGF (vascular endothelial growth factor) sub-family-a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PlGF (especially PlGF‑1) and some forms of VEGF can form dimers that decrease the angiogenic effect of VEGF on VEGF R2. PlGF‑2, like VEGF164 165, shows heparin‑dependent binding of neuropilin (Npn)‑1 and Npn‑2, and can inhibit nerve growth cone collapse. Circulating PlGF often correlates with tumor stage and aggressiveness, and therapeutic PlGF‑2 antibodies are being investigated for their ability to inhibit tumor growth and angiogenesis.

Expression system: HEK293 Cells
Length: 28-193, Full Length of Mature Protein
Activity: Cell Activity

Expression system: HEK293 Cells
Length: 22-353, Full Length of Mature Protein
Activity: Cell Activity

Expression system: E. coli
Length: 1-128, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 23-957, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 19-569, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-507, Full Length
Activity: Not Tested

CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 5.0 kDa and the accession number is P25063-1.