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Search Results for " reperfusion "

20

Compounds

Cat No. Product Name Synonyms Targets
T3672 Nomilin MAPK
Nomilin is naturally occurring triterpenoids, have immunomodulatory activity.
TN1895 Luteolinidin chloride CD38
Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.
T3102 NS-1619 Apoptosis , Potassium Channel
NS1619 have cardio-protective effects after ischemia-reperfusion injury.
T9073 SRS16-86 Ferroptosis
SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.
T5575 Cycloastragenol Cyclogalegenol,Astramembrangenin Epigenetic Reader Domain , Telomerase
Astramembrangenin (Cycloastragenol (Astramembrangenin)) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloastragenol (CAG) may have a novel therape...
T2058 Palosuran ACT-058362 GPR
Palosuran (ACT-058362) (ACT-058362) is a new potent and specific antagonist of the human UT receptor.
T22537 9-Phenanthrol TRP/TRPV Channel
9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.
T9714 Atpenin A5 Potassium Channel
Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1].
T9765 TJ-M2010-5 MyD88
TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.
T24109 GSK329 GSK 329,GSK-329 Others
GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury.
TN6490 Regaloside C Others
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties.
T9232 Mitochondrial fusion promoter M1 Mitochondrial Metabolism
Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardia...
T1677 Montelukast Singular Leukotriene Receptor , Lipoxygenase , LTR
Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury...
T4612 NS309 EGFR , Potassium Channel , HER
NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activat...
T23521 VULM 1457 Acyltransferase
VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM1457 significantly reduces production and secretion of...
T1677L Montelukast sodium MK0476 Leukotriene Receptor , LTR
Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver i...
T14186 17-ODYA Alkynyl Stearic Acid Others , PROTAC Linker
17-ODYA (Alkynyl Stearic Acid) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
T6547 Ipratropium Bromide Sch 1000,Itrop,Atrovent AChR
Ipratropium Bromide (Sch 1000) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis and emphysema.
T1479 Isosorbide dinitrate Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate Others , NO Synthase
Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.
T3890 Verbenalin Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin Others
Verbenalin (Verbenaloside) induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis.
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TargetMol