p32

p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.

P32/98 hemifumarate is a dipeptidyl peptidase IV (DPP4) inhibitor with hypoglycemic properties that improves insulin sensitivity and β-cell responsiveness in the Zucker diabetic rat model, and may be useful in studies of type 2 diabetes and colitis.

C5aR2 agonist P32 (Ac-RHYPYWR-OH) is a selective agonist for C5aR2. It has demonstrated the ability to trigger various immunomodulatory activities both in vitro and in vivo, as it can downregulate C5aR1-mediated cellular signaling and can also operate in a C5aR1-independent manner.

C5aR2 agonist P32 acetate (Ac-RHYPYWR-OH), a selective agonist for C5aR2, has been shown to induce various immunomodulatory activities both in vitro and in vivo. It modulates cell signaling via the downregulation of C5aR1-mediated pathways and can also function independently of C5aR1.

BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).

BIBP3226 is a potent and selective antagonist for the Neuropeptide Y receptor (Y1) and the neuropeptide FF receptor (NPFF).

GP3269 is a selective, potent, orally active human adenosine kinase (AK) inhibitor (IC50: 11 nM) with anticonvulsant effects in rats.

Mouse IgG2A(L234A/L235A/P329G)-Kappa Isotype-control is the isotype control for Mouse IgG2A-Kappa antibody.

Human IgG4(S228P/L235E/P329G)-kappa Isotype control is the isotype control for Human IgG4(S228P/L235E/P329G)-kappa antibody.

Human IgG1(P329G/E356D/M358L)-kappa Isotype control is the isotype control for Human IgG1(P329G/E356D/M358L)-kappa antibody.

Human IgG1(L234A /L235A/P329G)-Kappa Isotype control is the isotype control for Human IgG1 (LALAPG)-Kappa antibody.

DP32 is a dual-function compound incorporating an opioid receptor (MOP) agonist and a neuropeptide FF receptor (NPFFR) antagonist. It is applicable in analgesia-related research.

(D-Trp32)-Neuropeptide Y (porcine) is a highly selective agonist of the neuropeptide Y (NPY) Y5 receptor. It exhibits appetite-stimulating activity and can inhibit Forskolin-induced cAMP formation.

Tofimilast (CP-325366), a PDE4 inhibitor, is used potentially for the treatment of asthma and chronic obstructive pulmonary disease.

D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator

Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.

Zaurategrast ethyl ester is the ethyl ester prodrug of CT7758 and is an α4β1/α4β7 integrin antagonist. It is used for the treatment of inflammatory and autoimmune disorders.

Agerafenib hydrochloride, a highly potent inhibitor of BRAFV600E (Kd: 14 nM), demonstrates significant efficacy.

Mizagliflozin is an orally active, selective SGLT1 inhibitor with a Ki value of 27 nM for human SGLT1. Mizagliflozin is 303 times more selective for SGLT1 than for SGLT2. Mizagliflozin is an anti-diabetic drug that can improve postprandial blood sugar fluctuations and may have the potential to improve chronic constipation.

Pirolate is a receptor of histamine H1.

NP3-253 is an orally active NLRP3 inhibitor that can cross the blood-brain barrier. It serves as a tool for further exploring the biological properties of NLRP3 in models of peripheral and neuroinflammation.

Agerafenib (CEP32496) is a highly potent inhibitor of BRAF.

Dihydrocarminomycin is an anthracycline antibiotics.

DMP 323 is a potent inhibitor of HIV-1 protease.