membrane-permeable — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T81824	Membrane-Permeable Sequence, MPS
	Membrane-Permeable Sequence (MPS) is a cell-penetrating peptide (CPP) utilized in the investigation of membrane crossing mechanisms [1].
T40996	Coppersensor 1	Coppersensor 1,CS1	Others
	Coppersensor 1 (CS1) is a boron dipyrromethene-based fluorescent sensor for selective and sensitive detection of copper(I) ions (Cu + ) in biological samples. Coppersensor 1 can be imaged using any type of fluorescence m...		Others
T64345	4-(Dimethylamino)phenol		Others
	4-(Dimethylamino)phenol enhances extracellular lactate dehydrogenase (LDH) levels without significant effects on gluconeogenesis. Only when the membrane becomes permeable to LDH does 4-(Dimethylamino)phenol reduce ATP co...		Others
T16357	DA-3003-1	NSC 663284	Phosphatase
	DA-3003-1 (DA-3003-1) is a membrane-permeable, potent and selective Cdc25 dual specificity phosphatase inhibitor with antitumor activity that inhibits Cdc25B2, Cdc25A, Cdc25B2 and Cdc25C.		Phosphatase
T2661	TGX-221	TGX221	PI3K
	TGX-221, an effective, specific, and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit, is utilized for cancer treatment.		PI3K
T14064	8-Bromo-cGMP sodium		Calcium Channel , PKA
	8-Bromo-cGMP sodium is a PKG activator, a membrane-permeable analog of cGMP. 8-Bromo-cGMP sodium has pain-relieving and vasodilatory effects, significantly inhibits Ca2+ macroscopic currents, and inhibits high K+-stimula...		Calcium Channel , PKA
T71961	TUN-92046	DM-α-KG,T71961,Dimethyl 2-ketoglutarate,Dimethyl 2-oxoglutarate	Others
	TUN-92046 (Dimethyl 2-oxoglutarate) is a membrane-permeable alpha-ketoglutarate analogue that inhibits maladaptive autophagy in pressure overloading induced cardiomyopathy.		Others
T8341	QX 314	QX-314	Others
	QX 314 (Lidocaine N-ethyl bromide) is a blocker of non-membrane-permeable,and Inhibits Acid-Induced Activation of Esophageal Nociceptive C Fiber Neurons.		Others
T3358	ITSA-1	ITSA1	HDAC
	ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but shows no activity towards other HDAC inhibitors.		HDAC
T14496	BAMB-4	ITPKA-IN-C14	Others
	BAMB-4 (ITPKA-IN-C14) is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA). It acts by suppressing the metastasis-promoting effect of ITPKA in lung tumor cells(with IC50 of 37 μM in...		Others
T15660	KHK-IN-1	KHK-IN-8,Ketohexokinase inhibitor 8	Others
	KHK-IN-1 (KHK-IN-8) is a selective and cell membrane permeable inhibitor of ketohexokinase (KHK, IC50=12 nM; F=34%). KHK-IN-1 inhibits F1P production in HepG2 cell lysates with IC50 of 400 nM. KHK-IN-1 has potential for ...		Others
T15176	DSS Crosslinker		Others
	DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters a...		Others
T6564	Leupeptin Hemisulfate		Serine Protease , Cysteine Protease
	Leupeptin hemisulfate is a protease inhibitor with cell membrane-permeable, reversible, competitive, and oral activities. Leupeptin hemisulfate inhibits the activity of Cathepsin B, Cathepsin H, and Cathepsin L, and bloc...		Serine Protease , Cysteine Protease
T6040	Aloxistatin	E64d,Loxistatin,E64c ethyl ester	SARS-CoV , Cysteine Protease
	Aloxistatin (E64d) is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with...		SARS-CoV , Cysteine Protease
T14989	CMPD101		ROCK , GRK , PKC
	CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with I...		ROCK , GRK , PKC
T21992	Vacuolin-1		PI3K , Autophagy
	Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits ...		PI3K , Autophagy
T60352	ML089		Others
	ML089 (CID-22416235) is an orally available and potent, selective inhibitor of phosphomannose isomerase (PMI), with potential inhibition of other PMI immediate homologs.ML089 is a membrane-permeable probe for the study o...		Others
T12263L	NSC305787 hydrochloride	(Rac)-NSC305787 hydrochloride	Others
	NSC305787 hydrochloride ((Rac)-NSC305787 hydrochloride is a cell membrane permeable and selective and potent small molecule dual inhibitor of Cdc25 dual specificity phosphatase and EZR that displays antitumor activity in...		Others
T6301	Tosedostat	CHR-2797	Aminopeptidase , AChR
	Tosedostat (CHR-2797) is an orally bioavailable inhibitor of the M1 family of aminopeptidases with potential antineoplastic activity. Tosedostat is converted intracellularly into a poorly membrane-permeable active metabo...		Aminopeptidase , AChR
T37020	Endosidin-2	ES2,Endosidin 2
	Endosidin-2 is an exocyst inhibitor, a cell-permeable benzylidene benzoylhydrazine, that binds to the exocyst component of the 70 kDa (EXO70) subunit of the exocyst complex (Kd = 253 μM, EXO70A1).Endosidin-2 disrupts pro...