m 15

M 15 liquid crystals are a member of the oxycyanobiphenyl family, which exhibits a liquid crystalline phase in the temperature range of 47-67.5℃.

1650-M15 serves as an inhibitor of lipoteichoic acid synthase (LtaS) and targets Gram-positive bacteria, exhibiting no substantial inhibitory action against Gram-negative bacteria. The compound has IC50 values of 62.44 μM and 66.42 μM against MRSA and MSSA, respectively, with MICs for both being 200 μM.

m-PEG15-alcohol is a PEG-based linker for PROTACs, joining two essential ligands [crucial for forming PROTAC molecules], and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG15-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG15-acetic acid is a PROTAC linker classified under the PEG category, suitable for synthesizing PROTAC molecules.

C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) is a lipid molecule that can be used in life science related research. The CAS number of C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) is 1246298-58-7.

BAM 15 is an uncoupler of mitochondrial protonophore.

SM 15178 is a leukotriene B4 antagonist.

CFM 1571 hydrochloride is a chemical compound that acts as a stimulator of the nitric oxide receptor known as soluble guanylate cyclase (sGC). It demonstrates an EC50 value of 5.49 μM and an IC50 value of 2.84 μM. Soluble guanylate cyclase is an important signal-transduction enzyme that is activated by nitric oxide. The compound CFM 1571 hydrochloride shows potential for use in cardiovascular and other disease research [1] [2].

BM 15766 sulfate, an inhibitor of 7-dehydrocholesterol δ7-reductase, effectively reduces plasma cholesterol levels and functions as a hypolipidemic agent [1] [2].

CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.

BM152054 is a potent PPARγ ligand that induces glucose utilization in peripheral tissues by enhancing insulin action.

Vedaprofen (PM 150) inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli sliding clamp with the IC50 of 222 μM and Ki of 131 μM.

Avibactam sodium (NXL-104) is a non-β-lactam β-lactamase inhibitor that inhibits TEM-1, P99, and KPC-2 β-lactamases (IC50=8/80/38 nM) covalently and reversibly. Avibactam sodium has antimicrobial activity and can be used to treat urinary tract infections.

Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.

Naftopidil (KT-611) (INN, marketed under the brand name Flivas), an antihypertensive medicine, is used as a selective α1-adrenergic receptor antagonist or α-blocker.

Bezafibrate (BM15075) is an antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES. It decreases LOW-DENSITY LIPOPROTEINS and increases HIGH-DENSITY LIPOPROTEINS.

Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.

cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride (Quaternium-15 cis-form) is an antimicrobial agent used in cosmetics as a cosmetic preservative and antistatic agent.cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride is an oral teratogen, but not a dermal teratogen, and has been dosed in rats at doses exceeding the expected cumulative exposures for cosmetics.

Avibactam free acid is a potent β-lactamase inhibitor exhibiting covalent and reversible properties, capable of inhibiting TEM-1, P99, and CTX-M-15 at nanomolar concentrations. Avibactam free acid and Ceftazidime may be combined for treating urinary tract infections.

FPI-1523 sodium, a derivative of avibactam, is a potent β-lactamase inhibitor with Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. It inhibited PBP2 with an IC50 of 3.2 μM and has a high level of antibacterial and considerable antimicrobial activity.

Avibactam sodium hydrate (NXL-104 hydrate) is a highly effective β-lactamase inhibitor that inhibits β-lactamases TEM-1 and CTX-M-15, as well as the carbapenemase produced by Klebsiella pneumoniae and carbapenem-resistant Enterobacteriaceae.

YM158 free base is a potent and selective antagonist of the TXA2 and LTD4 receptors (pA2 values of approximately 8.81 and 8.87).

ORM-15341 is a potent and full antagonist for human AR (hAR)( with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells)