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(11)
By Target- Apoptosis
- Autophagy(7)
- DNA/RNA Synthesis(5)
- NF-κB(5)
- Ferroptosis(4)
- CDK(3)
- Caspase(3)
- Endogenous Metabolite(3)
- Nrf2(3)
- Others(40)
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Results for "
cisplatin
" in TargetMol Product Catalog- Inhibitors & Agonists92
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Cisplatin
cis-Diaminodichloroplatinum, CDDP
T156415663-27-1
Cisplatin (CDDP) is a chemotherapeutic agent with antitumor activity and is a classic DNA crosslinker. It inhibits DNA synthesis and induces DNA damage in cancer cells by forming DNA adducts, ultimately leading to cell death. In addition, Cisplatin can activate ferroptosis and induce autophagy. In animal studies, it is commonly used to establish models of chronic kidney injury and acute renal failure.
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