T9724 |
WAY-340935
|
|
Others
|
|
WAY-340935 has anti-inflammatory and analgesic activities. |
T6996 |
SU 5402
|
SU5402 |
PDGFR
,
FGFR
,
VEGFR
|
|
SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, F... |
T2642 |
PD173074
|
|
IGF-1R
,
Apoptosis
,
EGFR
,
FGFR
,
Src
,
VEGFR
|
|
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. ... |
T16975 |
TAK-593
|
|
PDGFR
,
VEGFR
|
|
TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGF... |
T5466 |
Tyrosine kinase-IN-1
|
|
VEGFR
,
FLT
,
PDGFR
,
FGFR
|
|
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM,... |
T6012 |
SAR131675
|
SAR 131675 |
VEGFR
|
|
SAR 131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM. |
T2446 |
KI8751
|
|
EGFR
,
FGFR
,
c-Kit
,
PDGFR
,
VEGFR
|
|
KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM. |
T5475 |
ZD-4190
|
|
EGFR
,
VEGFR
|
|
ZD-4190 is a inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor... |
T3570 |
SU4312
|
NSC 86429,SU 4312 |
PDGFR
,
VEGFR
|
|
SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.... |
T3476 |
JI-101
|
JI 101,CGI-1842 |
PDGFR
,
Ephrin Receptor
,
VEGFR
|
|
JI-101 is an oral multi-kinase inhibitor that targets vascular endothelial growth factor receptor type 2 (VEGFR-2), plat... |
T8213 |
Isolinderalactone
|
|
NOS
,
STAT
|
|
Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, wi... |
T9979 |
WAY-302159
|
|
VEGFR
|
|
WAY-302159 is a VEGFR2 inhibitor. |
T12598 |
Pz-1
|
|
c-RET
,
VEGFR
|
|
Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply req... |
T3566 |
SU5205
|
SU 5205 |
VEGFR
|
|
SU 5205 is a VEGFR2 inhibitor. |
T3599 |
BFH772
|
BFH-722 |
VEGFR
|
|
BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeti... |
T4425 |
JK-P3
|
|
VEGFR
|
|
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has... |
T15185 |
Lucitanib
|
E-3810 |
FGFR
,
VEGFR
|
|
Lucitanib is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FG... |
T4318 |
EOC317
|
ACTB1003,ACTB 1003,ACTB-1003 |
Tie-2
,
FGFR
,
VEGFR
|
|
ACTB-1003 is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2). |
T7945 |
SU14813
|
|
PDGFR
,
c-Kit
,
VEGFR
|
|
SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, ... |
T1777 |
Nintedanib
|
Intedanib,BIBF 1120 |
PDGFR
,
VEGFR
,
Src
,
FLT
,
FGFR
|
|
Nintedanib is an inhibitor of the receptor tyrosine kinases VEGFR/FGFR/PDGFR (IC50s: 13-34/37-610/59/65 nM for VEGFR1-3,... |