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Reverse Transcriptase

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Suramin Sodium Salt
Suramin hexasodium salt, NF-060, BAY-205
T2160129-46-4
Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis.
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TargetMol | Inhibitor Hot
Zalcitabine
Ro 24-2027 000, NSC 606170, Dideoxycytidine, ddC, 2',3'-Dideoxycytidine
T01107481-89-2
Zalcitabine (Dideoxycytidine)(Dideoxycytidine;ddC; 2', 3'-Dideoxycytidine) is a nucleoside analog reverse transcriptase inhibitor (NRTI); At low concentrations, It can potently inhibit HIV replication by binding to reverse transcriptase terminated synthesis of viral DNA chain.
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Lamivudine
GR109714X, BCH-189
T0682134678-17-4
Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
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Salicylanilide
WR10019, 2-Hydroxybenzanilide
T075387-17-2
Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.
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Stavudine
Sanilvudine, NSC 163661, d4T, BMY-27857
T14043056-17-5
Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.
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Telbivudine
NV 02B, L-Thymidine, Epavudine
T15133424-98-4
Telbivudine (NV 02B) is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of telbivudine is as a Nucleoside Reverse Transcriptase Inhibitor. The chemical classification of telbivudine is Nucleoside Analog.
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Tenofovir
TDF, PMPA, GS 1278
T1649147127-20-6
Tenofovir (GS 1278) is an adenine analog REVERSE TRANSC-RIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.
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Didanosine
ddI, 2',3'-Dideoxyinosine
T257869655-05-6
Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).
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Daidzin
NPI-031D, Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside
T2901552-66-9
Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
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Methyl gallate
NSC 363001, Gallincin, Gallicin, Gallic acid methyl ester
T373099-24-1
Methyl gallate (Gallincin) is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
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2,2'-Anhydrouridine
O2,2'-Cyclouridine, 2,2'-Cyclouridine
T59813736-77-4
2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies.
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TargetMol | Inhibitor Sale
Abacavir sulfate
Ziagen, ABC sulfate, Abacavir Hemisulfate, 1592U89
T6367188062-50-2
Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity
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Gramine
NSC 16892, Donaxine
T651987-52-5
Gramine (Donaxine), a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist. Gramine has anti-tumor, anti-viral and anti-inflammatory properties.
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Azvudine
RO-0622, FNC
T144891011529-10-4
Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM).
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EFdA-TP tetrasodium
T724612883783-00-2
EFdA-TP tetrasodium, a potent nucleoside reverse transcriptase (RT) inhibitor, effectively halts RT-catalyzed DNA synthesis by acting as an immediate or delayed chain terminator (ICT or DCT). It employs multiple mechanisms to inhibit HIV-1 RT [1].
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10-14 weeks
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Emtricitabine triphosphate tetrasodium salt
(-)-Emtricitabine triphosphate tetrasodium salt
T781311188407-46-6
Emtricitabine triphosphate tetrasodium salt is the tetrasodium form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleoside reverse transcriptase inhibitor effective against HIV and HBV [1].
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8-10 weeks
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ddUTP
2′,3′-Dideoxyuridine-5′-triphosphate
T7957984445-38-5
ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) is a selective inhibitor of HIV and AMV reverse transcriptases, with Ki values of 0.05 µM for HIV and 1 µM for AMV. It is preferentially incorporated at dTTP sites within the DNA strand, thereby preventing further chain elongation [1].
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8-10 weeks
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MK-6186
T681031034474-19-5In house
MK-6186 is a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity for the study of viral infections.
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Hypericin
Hypericine, Cyclosan
T6S0923548-04-9
Hypericin (Cyclosan) is a natural anthraquinone compound, an extract of Hypericum perforatum, which inhibits PKC, MAO, dopamine-beta-hydroxylase, reverse transcriptase, telomerase, and CYP, etc. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant activities.
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hiv-1 inhibitor-6 
3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-
T98541821309-39-0
HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication.
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Reverse transcriptase-IN-1
T127152380001-43-2
Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7 nM.
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6-8 weeks
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TargetMol | Inhibitor Sale
reverse transcriptase-in-3
T72203
Reverse transcriptase-IN-3, a pyrimidine-5-carboxamide derivative, functions as an inhibitor of HIV-1, demonstrating potent activity against both wild-type and mutant strains of HIV-1.
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6-8 weeks
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Reverse transcriptase-IN-4
T72206
Reverse transcriptase-IN-4 is a potent, selective non-nucleoside reverse transcriptase (NNRT) inhibitor, demonstrating an EC50 of 0.053 μM against wild-type HIV-1 and 0.26 μM for the E138K HIV-1 mutant.
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6-8 weeks
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Adefovir diphosphate 2TEA
PMEA diphosphate, GS-0393 diphosphate, Adefovir diphosphate 2TEA(129556-87-2 Free base)
T71036L
Adefovir diphosphate 2TEA is the salt form of Adefovir diphosphate.Adefovir diphosphate is a metabolite of Adefovir (GS-0393,PMEA) and cyclic nucleoside phosphonate (ANP) analog , an orally available reverse transcriptase inhibitor with antiviral activity against herpes, hepatitis B, and human immunodeficiency virus (HIV).
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