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Search Results for " kallikrein "

20

Compounds

Cat No. Product Name Synonyms Targets
T73611 Kallikrein
Kallikrein is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides , respectively [1] .
T40312 Plasma kallikrein-IN-1
Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.
T63796 Kallikrein-IN-2
Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein.
T63579 Kallikrein-IN-1
Kallikrein-IN-1 (Formula A) is an inhibitor of the kinin-releasing enzyme Kallikrein.
T61403 Plasma kallikrein-IN-3
Plasma kallikrein-IN-3, a potent inhibitor ( IC 50 : 0.15 μM) of plasma kallikrein, finds application in research related to hereditary angioedema, diabetic macular edema, and diabetic retinopathy [1].
T72337 Plasma kallikrein-IN-2
Plasma kallikrein-IN-2, a potent inhibitor of plasma kallikrein (PKal) with an inhibitory concentration (IC) 50 value of 0.1 nM, is utilized in research targeting hereditary angioedema, diabetic macular edema, and diabet...
T72624 Kallikrein 5-IN-2
Kallikrein 5-IN-2 is a potent inhibitor of Kallikrein KLK5, exhibiting selectivity with a pIC50 value of 7.1. By inhibiting KLK5, it has the potential to normalize epidermal shedding, thereby reducing associated inflamma...
T11885 LSP-249 Others
LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell.
T3359 Aprotinin Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin Others , Serine Protease , Influenza Virus , Proteasome
Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat...
T14358 Avoralstat BCX4161 Others
Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.
T39350 Sebetralstat KVD900 Others
Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases.
T6370 AEBSF hydrochloride AEBSF HCl,Pefabloc SC Thrombin , Serine Protease , Influenza Virus
AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.
TP1792L KKI-5 acetate(97145-43-2 free base) Serine Protease
KKI-5 acetate is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.
T0372 Gabexate mesylate FOY Factor Xa , Serine Protease , Proteasome
Gabexate mesylate (FOY) is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inh...
T68173 ZD-2138 Ici-D2138 Lipoxygenase
ZD-2138 is a potent and selective specific inhibitor of 5-lipoxygenase (5-LOX) that inhibits allergen-induced pulmonary bronchoconstriction and reduces neurally-induced fast-acting kallikrein-ergic constriction of isolat...
T21610 Bradykinin (acetate) Bradykinin Receptor
Bradykinin (acetate) is an active peptide that is generated by the kallikrein-kinin system. It is a inflammatory mediator and also recognized as a neuromediator and regulator of several vascular and renal functions. Enzy...
T70161 Berotralstat HCl
Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated wi...
TP1379 KKI-5 TFA(97145-43-2 free base) KKI-5 (TFA)
KKI-5 (TFA) is a specific tissue kallikrein inhibitor.Kki-5 (TFA) can reduce breast cancer cell infiltration.
T71417 LM-030
LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).
T80271 Irucalantide
Irucalantide is a kallikrein inhibitor [1].
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