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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T73611 | Kallikrein | ||
Kallikrein is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides , respectively [1] . | |||
T40312 | Plasma kallikrein-IN-1 | ||
Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM. | |||
T63796 | Kallikrein-IN-2 | ||
Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein. | |||
T63579 | Kallikrein-IN-1 | ||
Kallikrein-IN-1 (Formula A) is an inhibitor of the kinin-releasing enzyme Kallikrein. | |||
T61403 | Plasma kallikrein-IN-3 | ||
Plasma kallikrein-IN-3, a potent inhibitor ( IC 50 : 0.15 μM) of plasma kallikrein, finds application in research related to hereditary angioedema, diabetic macular edema, and diabetic retinopathy [1]. | |||
T72337 | Plasma kallikrein-IN-2 | ||
Plasma kallikrein-IN-2, a potent inhibitor of plasma kallikrein (PKal) with an inhibitory concentration (IC) 50 value of 0.1 nM, is utilized in research targeting hereditary angioedema, diabetic macular edema, and diabet... | |||
T72624 | Kallikrein 5-IN-2 | ||
Kallikrein 5-IN-2 is a potent inhibitor of Kallikrein KLK5, exhibiting selectivity with a pIC50 value of 7.1. By inhibiting KLK5, it has the potential to normalize epidermal shedding, thereby reducing associated inflamma... | |||
T11885 | LSP-249 | Others | |
LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell. | |||
T3359 | Aprotinin | Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin | Others , Serine Protease , Influenza Virus , Proteasome |
Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat... | |||
T14358 | Avoralstat | BCX4161 | Others |
Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema. | |||
T39350 | Sebetralstat | KVD900 | Others |
Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases. | |||
T6370 | AEBSF hydrochloride | AEBSF HCl,Pefabloc SC | Thrombin , Serine Protease , Influenza Virus |
AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin. | |||
TP1792L | KKI-5 acetate(97145-43-2 free base) | Serine Protease | |
KKI-5 acetate is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema. | |||
T0372 | Gabexate mesylate | FOY | Factor Xa , Serine Protease , Proteasome |
Gabexate mesylate (FOY) is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inh... | |||
T68173 | ZD-2138 | Ici-D2138 | Lipoxygenase |
ZD-2138 is a potent and selective specific inhibitor of 5-lipoxygenase (5-LOX) that inhibits allergen-induced pulmonary bronchoconstriction and reduces neurally-induced fast-acting kallikrein-ergic constriction of isolat... | |||
T21610 | Bradykinin (acetate) | Bradykinin Receptor | |
Bradykinin (acetate) is an active peptide that is generated by the kallikrein-kinin system. It is a inflammatory mediator and also recognized as a neuromediator and regulator of several vascular and renal functions. Enzy... | |||
T70161 | Berotralstat HCl | ||
Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated wi... | |||
TP1379 | KKI-5 TFA(97145-43-2 free base) | KKI-5 (TFA) | |
KKI-5 (TFA) is a specific tissue kallikrein inhibitor.Kki-5 (TFA) can reduce breast cancer cell infiltration. | |||
T71417 | LM-030 | ||
LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2). | |||
T80271 | Irucalantide | ||
Irucalantide is a kallikrein inhibitor [1]. |