205
14
109
6
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10852 | CNS-5161 hydrochloride | CNS 5161A | NMDAR |
CNS-5161 hydrochloride (CNS 5161A) is a new antagonist of NMDA ion-channel. It interacts with the NMDA receptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate. | |||
T27055 | CNS-5161 | CNS 5161 | |
CNS-5161 is an NMDA antagonist. | |||
T69411 | CNS-5788 | ||
CNS-5788 is a potential ischemia-selective N-methyl-D-aspartate (NMDA) receptor ion-channel blocker | |||
T26645 | Aptiganel | CNS-1102,CNS 1102,Cerestat,CNS1102 | |
Aptiganel acts as a noncompetitive NMDA antagonist with neuroprotective effects. | |||
T0183L | Pramiracetam Sulfate | CNS-1879,CI879,CI-879,CI 879,Pramiracetam | |
Thurfyl salicylate is a reddening agent for the treatment of musculoskeletal, joint, periarticular, and soft tissue pain. | |||
T9786 | Lu AF27139 | P2X Receptor | |
Lu AF27139 is an effective and selective antagonist of P2X7 receptor (IC50s of 12 and 2.4 nM for human and rat, Kis of 22, 54, and 13 nM for mouse, human, and rat, respectively). Lu AF27139 can be used in CNS diseases st... | |||
T7626 | Budipine | Others | |
Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent. | |||
T7688 | 4-Nonylphenylboronic acid | FAAH | |
4-Nonylphenylboronic acid is a inhibitor of FAAH. | |||
T9697 | ASK1-IN-1 | ASK | |
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays. | |||
T7946 | AER-271 | Aquaporin | |
AER-271 is an inhibitor of aquaporin-4. | |||
T60003 | AC1-IN-1 | Adenylyl cyclase | |
AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM). | |||
T11689 | ITI-214 | ITI214 | PDE |
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = ... | |||
T7388 | GSK805 | ROR | |
GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor's putative ligand binding domain without exerting significant effects on DNA bindi... | |||
T9070 | ASP2905 | ASP-2905 | Potassium Channel |
ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene. It can cross the blood-brain barrier and has antipsychotic activities | |||
T2625 | MK-0752 | Beta Amyloid , Gamma-secretase | |
MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM). | |||
T5513 | RO-3 | P2X Receptor | |
RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor | |||
T1787 | Levobupivacaine | Sodium Channel | |
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZ... | |||
T2086 | ELN-441958 | ELN 441958 | Bradykinin Receptor |
ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. ELN-441958(ELN 441958) is highly selective for B1 over B2 receptors. | |||
T2026 | CYM5442 | S1P Receptor , LPL Receptor | |
CYM5442 is an S1P agonist, targeting to Sphingosine. | |||
T3119 | JNJ-63533054 | JNJ 63533054 | GPR |
JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM. | |||
T9149 | 2BAct | 2B-Act,2B Act | PERK |
2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response | |||
T6039 | TAK-285 | TAK285,TAK 285 | EGFR , MEK , HER , Aurora Kinase |
TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1. | |||
T16849 | SB-222200 | Neurokinin receptor | |
SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM). | |||
T21995 | XAP044 | GluR | |
XAP044 is a mGlu7-selective antagonist which inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice with a half-maximal blockade at 88 nm[1]. | |||
T1052 | Proglumide | cholecystokinin | |
Proglumide (Binoside) is a cholecystokinin antagonist, which blocks both the CCKA and CCKB subtypes. Proglumide is a drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is... | |||
T24984 | 5J-4 | Calcium Channel | |
5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE). 5J-4 reduces the production of IL-17 and decreases the expression of RORα and RORγt. | |||
T4316 | ML365 | Potassium Channel | |
ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3). | |||
T14835 | BTRX-335140 | CYM-53093 | Opioid Receptor |
BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. BTRX-335140... | |||
T14864 | Caracemide | NSC-253272 | Others , DNA/RNA Synthesis , Antibacterial |
Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies. | |||
T9713 | δ-secretase inhibitor 11 | Beta Amyloid , Caspase | |
δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment. | |||
T0682 | Lamivudine | GR109714X,BCH-189 | HIV Protease , Reverse Transcriptase |
Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease. | |||
T6566 | Levobupivacaine hydrochloride | Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,(S)-(-)-Bupivacaine monohydrochloride | Sodium Channel |
Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic... | |||
T24047 | Etilevodopa hydrochloride | Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester | Others , Dopamine Receptor , Drug Metabolite |
Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration. | |||
T0688 | Ganciclovir | BW 759,RS-21592,2'-Nor-2'-deoxyguanosine | Nucleoside Antimetabolite/Analog , Others , Antibiotic , Antifection , HSV |
Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegaloviru... | |||
T0370 | Pheniramine maleate | Daneral,Inhiston,Trimetose | 5-HT Receptor , Histamine Receptor |
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re... | |||
T22337 | Ganciclovir sodium | RS-21592 sodium,Cytovene IV sodium,2'-Nor-2'-deoxyguanosine sodium,BW 759 sodium | Nucleoside Antimetabolite/Analog , Others , Antifection , HSV |
Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1). | |||
T16800 | (RS)-AMPA | (±)-AMPA | iGluR |
(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid. | |||
T7065 | Tizanidine | Adrenergic Receptor | |
Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. | |||
T13323 | VU6012962 | GluR | |
VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM). | |||
T0290 | Tizanidine hydrochloride | Tizanidine HCl,DS 103-282 | Adrenergic Receptor |
Tizanidine hydrochloride (Tizanidine HCl), an α2-adrenergic receptor agonist, inhibits neurotransmitter release from CNS noradrenergic neurons. | |||
T1483 | Citalopram hydrobromide | Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr | 5-HT Receptor , Serotonin Transporter , Autophagy |
Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system... | |||
T5353 | ABX-1431 | Elcubragistat | Lipase |
ABX-1431 (Elcubragistat) is a selective and orally available CNS-penetrant monoacylglycerol lipase (MAGL/MGLL) inhibitor (IC50: 14 nM). | |||
T11175 | Elenbecestat | E2609 | Beta-Secretase , BACE |
Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease. | |||
T5411 | PDE10-IN-1 | SEP-0372814 | PDE |
PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders. | |||
T13321 | VU6005649 | GluR | |
VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively). | |||
T5494 | MW-150 | MW01-18-150SRM | p38 MAPK , Autophagy |
MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. | |||
T21470L | Davunetide acetate | Davunetide acetate(211439-12-2 Free base) | Beta Amyloid , Microtubule Associated |
Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicit... | |||
T12679 | (Rac)-VU 6008667 | Others , AChR | |
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) with IC50 of 1.8 μM and pIC50 of 5.75, has high CNS penetration. | |||
T5956 | VP3.15 dihydrobromide | GSK-3 , PDE | |
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE7- glycogen synthase kinase (GSK)3 inhibitor(with IC50s of 1.59 μM , 0.88 μM,respectively.) | |||
T12899L | SEP-363856 hydrochloride | SEP-856 hydrochloride | Others , 5-HT Receptor |
SEP-363856 hydrochloride (SEP-856 hydrochloride) is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects, has the potential to trea... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0508 | γ-Aminobutyric acid | Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid | GABA Receptor , Endogenous Metabolite |
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system. | |||
T15643 | Kainic acid | Others | |
In the CNS, Kainic acid is an effective agonist at excitatory amino acid receptor subtypes. | |||
T2209 | Serotonin hydrochloride | 5-HT hydrochloride,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride | 5-HT Receptor , Endogenous Metabolite , Transferase |
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM). | |||
T12139 | N-(3-Methoxybenzyl)Palmitamide | FAAH | |
N-(3-Methoxybenzyl)Palmitamide is a promising FAAH inhibitor, treatment of pain, inflammation and CNS degenerative disorders. | |||
TN1048 | Cnidilin | Knidilin | |
Cnidilin (Knidilin) is found in association with Angelica dahurica roots, has high BBB permeability and has pharmacokinetic potential in the treatment of CNS disorders. | |||
T3S2105 | N-Benzylpalmitamide | Macamide 1,N-Benzylhexadecanamide | Others , FAAH , Autophagy |
N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the treatment of pain, inflammation and CNS degenerative disorders... | |||
T7033 | Rosmanol | Antioxidant , COX | |
Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and a... | |||
TN2437 | Serotonin | 5-hydroxytryptamine,5-HT | Others , 5-HT Receptor , Endogenous Metabolite , Transferase |
Serotonin (5-hydroxytryptamine) is a natural product from animals | |||
T0848 | L-DOPA | Levodopa,3,4-Dihydroxyphenylalanine | Dopamine Receptor , Endogenous Metabolite |
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai... | |||
T23305 | Salsolinol-1-carboxylic acid | Others | |
amino acid that occurs naturally in the CNS | |||
T2S2363 | Corydine | IL Receptor , Antifection | |
Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant activities. Injected intravenously in ra... | |||
TMA0805 | Lupanine | ATPase , Potassium Channel , Calcium Channel | |
Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupanine improves glucose homeostasis by influencing KATP-chann... | |||
TN2084 | Piperitol | Others | |
Piperitol has in vitro antioxidant potential, it also exhibits a stronger CNS depressant effect than that of M. rotundifolia. | |||
T14831 | Bryostatin 1 | HIV Protease , PKC | |
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a CNS)permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein (Kis: 8.0... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00740 | SDF-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f... | |||
TMPY-02820 | SDF-1 Protein, Human, Recombinant (isoform a) | Human | E. coli |
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f... | |||
TMPY-02591 | SDF-1 Protein, Human, Recombinant | Human | E. coli |
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f... | |||
TMPY-02424 | Prolactin Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial... | |||
TMPY-04778 | Prolactin Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial... | |||
TMPJ-00135 | BDNF Protein, Human/Murine/Rat, Recombinant | Human,Mouse,Rat | E. coli |
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. I... | |||
TMPY-03425 | Tau Protein, Human, Recombinant (His) | Human | E. coli |
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are... | |||
TMPY-05510 | BDNF Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. B... | |||
TMPJ-01467 | Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) | Human | E.coli |
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ... | |||
TMPY-00751 | TrkB Protein, Human, Recombinant (His) | Human | HEK293 |
TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptor with intracellular tyrosine kin... | |||
TMPY-02231 | TrkB Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptor with intracellular tyrosine kin... | |||
TMPY-00432 | TREM-2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b... | |||
TMPY-01148 | TREM-2 Protein, Human, Recombinant (His) | Human | HEK293 |
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b... | |||
TMPY-01703 | TREM-2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b... | |||
TMPY-03467 | IFN-beta Protein, Mouse, Recombinant | Mouse | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPY-00831 | IFN-beta Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPY-03145 | IFN-beta Protein, Human, Recombinant | Human | CHO |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPK-00544 | TLR3 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, whi... | |||
TMPK-00480 | IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL... | |||
TMPK-00406 | TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated | Human | HEK293 |
TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, whi... | |||
TMPY-02946 | TAFA2/FAM19A2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
FAM19A2 belongs to the FAM19/TAFA family. FAM19/TAFA family members are chemokine-like proteins. The biological functions of TAFA family members remain to be determined, but there are a few tentative hypotheses. First, T... | |||
TMPK-00279 | RGMA Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its recept... | |||
TMPK-00278 | RGMA Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its recept... | |||
TMPY-01056 | Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Le... | |||
TMPY-01221 | Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc) | Mouse | HEK293 |
Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Le... | |||
TMPY-03175 | Claudin-11 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solut... | |||
TMPH-03756 | Wint7b Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta d... | |||
TMPY-03144 | Nogo Receptor/RTN4R Protein, Human, Recombinant (His) | Human | HEK293 |
Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Le... | |||
TMPY-01163 | Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Le... | |||
TMPH-02573 | WISP3/CCN6 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta d... | |||
TMPJ-01279 | TAFA4 Protein, Human, Recombinant (His) | Human | E. coli |
FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature FAM19A4 contains 10 regularly spaced cysteine res... | |||
TMPY-01856 | MGAT5 Protein, Human, Recombinant (His) | Human | HEK293 |
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, also known as Alpha-mannoside beta-1,6-N-acetylglucosaminyl-transferase, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferas... | |||
TMPH-00964 | ATP5PB Protein, Human, Recombinant (His & Myc) | Human | E. coli |
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger... | |||
TMPY-02184 | SDF-1 Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f... | |||
TMPY-03289 | SDF-1 Protein, Mouse, Recombinant | Mouse | E. coli |
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f... | |||
TMPY-02749 | SDF-1 Protein, Human, Recombinant (His) | Human | E. coli |
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f... | |||
TMPH-02576 | TAFA1/FAM19A1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is ... | |||
TMPY-04662 | MAG Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
The myelin-associated glycoprotein (MAG) contains five immunoglobulin-like domains and belongs to the sialic-acid-binding subgroup of the Ig superfamily. MAG is a transmembrane glycoprotein of 100kDa localized in myelin ... | |||
TMPY-04676 | MAG Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The myelin-associated glycoprotein (MAG) contains five immunoglobulin-like domains and belongs to the sialic-acid-binding subgroup of the Ig superfamily. MAG is a transmembrane glycoprotein of 100kDa localized in myelin ... | |||
TMPY-03580 | SDF-1 Protein, Canine, Recombinant | Canine | E. coli |
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f... | |||
TMPY-02569 | MAG Protein, Human, Recombinant (His) | Human | HEK293 |
The myelin-associated glycoprotein (MAG) contains five immunoglobulin-like domains and belongs to the sialic-acid-binding subgroup of the Ig superfamily. MAG is a transmembrane glycoprotein of 100kDa localized in myelin ... | |||
TMPY-03147 | MAG Protein, Human, Recombinant (hFc) | Human | HEK293 |
The myelin-associated glycoprotein (MAG) contains five immunoglobulin-like domains and belongs to the sialic-acid-binding subgroup of the Ig superfamily. MAG is a transmembrane glycoprotein of 100kDa localized in myelin ... | |||
TMPJ-00332 | TPA Protein, Human, Recombinant (His) | Human | Human Cells |
Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and peptidase S1 domain. It belongs... | |||
TMPJ-00990 | S100B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an i... | |||
TMPJ-01296 | SULT4A1 Protein, Human, Recombinant | Human | E. coli |
Sulfotransferase 4A1 (ST4A1) is a member of the Sulfotransferase 1 family. ST4A1 is highly expressed in the cerebral cortex and frontal lobe, but no expression is detected in the pancreas. ST4A1 is a brain-specific sulfo... | |||
TMPH-03010 | EsxB Protein, Mycobacterium tuberculosis, Recombinant (His) | Mycobacterium tuberculosis | Yeast |
Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause d... | |||
TMPJ-00827 | Tau-D Protein, Human, Recombinant (His) | Human | E. coli |
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. ... | |||
TMPY-00350 | Doppel/PRND Protein, Human, Recombinant (His) | Human | HEK293 |
Doppel (PRND) is a paralogue of the mammalian prion (PRNP) gene. It is abundant in testis and, unlike PRNP, it is expressed at low levels in the adult central nervous system (CNS). Besides, doppel overexpression correlat... | |||
TMPY-00347 | Doppel/PRND Protein, Human, Recombinant (hFc) | Human | HEK293 |
Doppel (PRND) is a paralogue of the mammalian prion (PRNP) gene. It is abundant in testis and, unlike PRNP, it is expressed at low levels in the adult central nervous system (CNS). Besides, doppel overexpression correlat... | |||
TMPY-00286 | Neuropeptide Y Protein, Human, Recombinant (hFc) | Human | HEK293 |
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | ||
---|---|---|---|
L5900 | CNS-Penetrant Compound Library | 516 compounds | |
A unique collection of 516 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L2600 | Neuronal Signaling Compound Library | 2540 compounds | |
A unique collection of 2540 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L7700 | Neural Regeneration Compound Library | 529 compounds | |
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening; | |||
L2800 | Serotonin Receptor-Targeted Compound Library | 275 compounds | |
A unique collection of 275 compounds targeting serotonin receptors for high throughput screening and high content screening; | |||
L4300 | Wnt/Hedgehog/Notch Compound Library | 240 compounds | |
A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening; | |||
L2610 | Neurotransmitter Receptor Compound Library | 1513 compounds | |
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening; |