Select your Country or Region

  • TargetMol | Compound LibraryArgentinaArgentina
  • TargetMol | Compound LibraryAustraliaAustralia
  • TargetMol | Compound LibraryAustriaAustria
  • TargetMol | Compound LibraryBelgiumBelgium
  • TargetMol | Compound LibraryBrazilBrazil
  • TargetMol | Compound LibraryBulgariaBulgaria
  • TargetMol | Compound LibraryCroatiaCroatia
  • TargetMol | Compound LibraryCyprusCyprus
  • TargetMol | Compound LibraryCzechCzech
  • TargetMol | Compound LibraryDenmarkDenmark
  • TargetMol | Compound LibraryEgyptEgypt
  • TargetMol | Compound LibraryEstoniaEstonia
  • TargetMol | Compound LibraryFinlandFinland
  • TargetMol | Compound LibraryFranceFrance
  • TargetMol | Compound LibraryGermanyGermany
  • TargetMol | Compound LibraryGreeceGreece
  • TargetMol | Compound LibraryHong KongHong Kong
  • TargetMol | Compound LibraryHungaryHungary
  • TargetMol | Compound LibraryIcelandIceland
  • TargetMol | Compound LibraryIndiaIndia
  • TargetMol | Compound LibraryIrelandIreland
  • TargetMol | Compound LibraryIsraelIsrael
  • TargetMol | Compound LibraryItalyItaly
  • TargetMol | Compound LibraryJapanJapan
  • TargetMol | Compound LibraryKoreaKorea
  • TargetMol | Compound LibraryLatviaLatvia
  • TargetMol | Compound LibraryLebanonLebanon
  • TargetMol | Compound LibraryMalaysiaMalaysia
  • TargetMol | Compound LibraryMaltaMalta
  • TargetMol | Compound LibraryMoroccoMorocco
  • TargetMol | Compound LibraryNetherlandsNetherlands
  • TargetMol | Compound LibraryNew ZealandNew Zealand
  • TargetMol | Compound LibraryNorwayNorway
  • TargetMol | Compound LibraryPolandPoland
  • TargetMol | Compound LibraryPortugalPortugal
  • TargetMol | Compound LibraryRomaniaRomania
  • TargetMol | Compound LibrarySingaporeSingapore
  • TargetMol | Compound LibrarySlovakiaSlovakia
  • TargetMol | Compound LibrarySloveniaSlovenia
  • TargetMol | Compound LibrarySpainSpain
  • TargetMol | Compound LibrarySwedenSweden
  • TargetMol | Compound LibrarySwitzerlandSwitzerland
  • TargetMol | Compound LibraryTaiwan,ChinaTaiwan,China
  • TargetMol | Compound LibraryThailandThailand
  • TargetMol | Compound LibraryTurkeyTurkey
  • TargetMol | Compound LibraryUnited KingdomUnited Kingdom
  • TargetMol | Compound LibraryUnited StatesUnited States
  • TargetMol | Compound LibraryOther CountriesOther Countries
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom oxygenations, reductions, and dehydrogenations, heteroatom dealkylations, hydroxylations, can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

  • Urolithin A
    T71741143-70-0
    Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties.
    • $42
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • CLOZAPINE N-OXIDE
    T449434233-69-7
    Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide is also a dopamine antagonist and selective muscarinic M4 receptor agonist.
    • $30
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
  • Isonicotinic acid
    Fr1375655-22-1
    Isonicotinic acid is a metabolite of Isoniazid.Isonicotinic acid is a useful isomer of nicotinic acid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the biotransformation also to be catalyzed by cytochrome P450 enzymes, such as CYP2C.
    • $41
    In Stock
    Size
    QTY
  • Mycophenolate Mofetil
    T6293128794-94-5
    Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).
    • $47
    In Stock
    Size
    QTY
  • DL-Laudanosine
    T81751699-51-0
    DL-Laudanosine (Laudanosine) is a recognized metabolite of atracurium and cisatracurium.
    • $42
    In Stock
    Size
    QTY
  • 3-Sulfopropanoic acid
    TN724644826-45-1
    3-Sulfopropanoic acid, a major metabolite of treprostinil and its prodrug ALZ-801, is an endogenous molecule present in the cerebrospinal fluid (CSF) of AD patients that inhibits the formation of Aβ42 oligomers.
    • $36
    In Stock
    Size
    QTY
  • Phosphoramide mustard
    T3841010159-53-2
    Phosphoramide mustard is a toxic metabolite of cyclophosphamide with anticancer activity and ovarian toxicity that induces DNA damage.
    • $293
    In Stock
    Size
    QTY
  • 6'-hydroxydihydrocinchonidine
    T775515962-19-6
    6'-hydroxydihydrocinchonidine is a metabolite of quinine, with antimicrobial and antitumor activity, and inhibitory effect on Trypanosoma brucei and Streptococcus pneumoniae.
    • $195
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • DP-1 hydrochloride
    T38961L1472616-35-5In house
    DP-1 hydrochloride is a degradation product of SDC-TRAP-0063, a fragment of Ganetespib, a heat shock protein 90 (HSP90) inhibitor with antitumor activity.
    • $172
    In Stock
    Size
    QTY
  • meta-Fexofenadine
    T12005479035-75-1
    meta-Fexofenadine (meta-MDL-16455) is an isomer of Fexofenadine.
    • $32
    In Stock
    Size
    QTY
  • LGE-899
    T207231221722-10-6In house
    LGE-899 (Sonidegib metabolite M48) is a main metabolite of Sonidegib which is an inhibitor of the hedgehog pathway. The Tmax of LGE-899(60 h) is much longer than Sonidegib.
    • $56
    In Stock
    Size
    QTY
  • AST5902 mesylate(2412155-74-7 free base)
    T8945L2412155-75-8
    AST5902 mesylate is principal metabolite of Alflutinib in vivo. AST5902 mesylate exerts antineoplastic activity.
    • $137
    In Stock
    Size
    QTY
  • Didesethyl chloroquine
    T110394298-14-0In house
    Didesethyl chloroquine (Bisdesethylchloroquine) is an effective myocardial inhibitor. Didesethyl chloroquine (Bisdesethylchloroquine) is the main metabolite of the antimalarial drug chloroquine.
    • $179
    In Stock
    Size
    QTY
  • GS-829845
    T679051257705-09-1In house
    GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-life than the parent.
    • $39
    In Stock
    Size
    QTY
  • 2-Hydroxy atorvastatin calcium salt
    TQ0045265989-46-6In house
    2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt which is a potent HMG-CoA reductase inhibitor (IC50 = 8 nM).
    • $122
    In Stock
    Size
    QTY
  • 4-Hydroxymephenytoin
    T1014761837-65-8In house
    4-Hydroxymephenytoin ((+/-)-4'-Hydroxymephenytoin) is the metabolism of an antiepileptic drug mephenytoin. Mephenytoin is used as a CYP2C19 substrate.
    • $39
    In Stock
    Size
    QTY
  • Allopurinol riboside
    T1353916220-07-8In house
    Allopurinol riboside is a metabolite of allopurinol with potency against parasites. Allopurinol riboside competitively inhibits the action of purine nucleoside phosphorylase on inosine with a Ki of 277 μM.
    • $38
    In Stock
    Size
    QTY
  • Methotrexate metabolite
    T1604519741-14-1In house
    Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant.
    • $39
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • IMR-1A
    T3540331862-41-0
    IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.
    • $68
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Oseltamivir acid
    T5186187227-45-8
    Oseltamivir acid (GS4071) is a potent influenza virus neuraminidase inhibitor and the prodrug of GS4071.
    • $30
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Endoxifen
    T4281110025-28-0
    (E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for estrogen receptors than tamoxifen. As the efficient conversion of tamoxifen to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment.
    • $41
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Nortriptyline hydrochloride
    T1327894-71-3
    Nortriptyline hydrochloride (ELF-101 hydrochloride) is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
    • $33
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Clofibric acid
    T0061882-09-7
    Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
    • $31
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Gentisuric acid
    T8063525351-24-0
    Gentisuric acid, an Aspirin metabolite and a substrate of α-amidating monooxygenase (PAM), mitigates DNA damage induced by Mitomycin C. [1] [2]
    • Inquiry Price
    Size
    QTY
    TargetMol | Inhibitor Sale
  • 4-Desmethoxy Omeprazole
    T10138110374-16-8
    4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole is a proton pump inhibitor (PPI). Omeprazole shows competitive inhibition of CYP2C19 activity (Ki: 2 to 6 μM).
    • $133
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • p,p'-DDE
    T744072-55-9
    p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT
    • $58
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • 3-Hydroxycarbofuran
    T7858916655-82-6
    3-Hydroxycarbofuran, a principal metabolite of Carbofuran, acts as a reversible inhibitor of acetylcholinesterase (AChE) [1].
    • $170
    35 days
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Mebeverine acid
    T11986475203-77-1
    Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine and can be used as a marker of oral exposure to Mebeverine.
    • $73
    35 days
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Quercetin 7-glucuronide
    T8065838934-20-2
    Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a Quercetin metabolite found in Madagascarian Uncarina species, has the capability to inhibit LDL oxidation [1].
    • Inquiry Price
    Size
    QTY
    TargetMol | Inhibitor Sale
  • 16α-Hydroxyprednisolone
    T833913951-70-7
    16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide
    • $30
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • DDC 3′-O-β-D glucuronide
    T82599
    Compound 5, DDC 3′-O-β-D-glucuronide, is a drug metabolite with properties that inhibit the fibrillization and oligomerization of Aβ42, suggesting its potential utility in Alzheimer's disease research [1].
    • Inquiry Price
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Leukotriene D4
    T3812873836-78-9
    Leukotriene D4 (LTD4) is a potent pro-inflammatory mediator formed from arachidonic acid, a bronchoconstrictor, and induces osteoclast senescence.Leukotriene D4 induces transcriptional activity of potentially oncogenic genes and can be used in the study of asthma.
    • $287
    Backorder
    Size
    QTY
  • Omeprazole sulfide
    T268773590-85-9
    Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.
    • $33
    In Stock
    Size
    QTY
  • DCBA
    T854772236-23-8
    DCBA, an endogenous metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), is utilized to evaluate DEET exposure through its concentration levels in urine.
    • $39
    In Stock
    Size
    QTY
  • Ampyrone
    T005083-07-8
    Ampyrone (4-Aminoantipyrine) is a reagent for glucose determination in the presence of peroxidase and phenol.
    • $35
    In Stock
    Size
    QTY
  • N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide
    TN1352883715-22-8
    N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide ((9Z,12Z)-N-(3-Methoxybenzyl)octadeca-9,12-dienamide) is a Macamide impurity that may be used in the study of metabolic diseases.
    • $80
    In Stock
    Size
    QTY
  • Hydroxyhexamide
    T01503168-01-2
    Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.
    • $52
    In Stock
    Size
    QTY
  • Vinburnine
    T21494880-88-0
    Vinburnine (Eburnalritardo) is a vasodilator. Vinburnine is a vinca alkaloid and a metabolite of vincamine.
    • $39
    In Stock
    Size
    QTY
  • N-Desmethylclozapine
    T51586104-71-8
    N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist at δ-opioid receptors.
    • $34
    In Stock
    Size
    QTY
  • p-Coumaric Acid Ethyl Ester
    T138087362-39-2
    p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate) is the ethyl ester of p-Coumaric acid. p-Coumaric Acid is a common dietary polyphenol and also a potent immunosuppressive agent in treating autoimmune inflammatory diseases like rheumatoid arthritis.
    • $39
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Deslanoside
    T818317598-65-1
    Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations.
    • $80
    In Stock
    Size
    QTY
  • Perindopril acyl-β-D-glucuronide
    T78136120398-66-5
    Perindopril acyl-β-D-glucuronide is a metabolite of the ACE inhibitor perindopril [1].
    • Inquiry Price
    Size
    QTY
  • RPR132595A hydrochloride
    T78069
    RPR132595A (NPC) hydrochloride, an active metabolite of CPT-11, is produced via cytochrome P-450 3A4 (CYP3A4) metabolism and is ultimately eliminated via urinary excretion [1].
    • Inquiry Price
    Size
    QTY
  • N-Desmethyl imatinib
    T11641404844-02-6
    N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.
    • $84
    In Stock
    Size
    QTY
  • Norverapamil hydrochloride
    T1633967812-42-4
    Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.
    • $31
    In Stock
    Size
    QTY
  • GS-443902
    T55391355149-45-9
    GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at least 12 weeks
    • Inquiry Price
    Size
    QTY
  • N-desmethyl Olanzapine
    T35716161696-76-0
    N-desmethyl Olanzapine is a metabolite of the atypical antipsychotic compound Olanzapinec, which is formed through the oxidative metabolism of olanzapine by the cytochrome 450 (CYP) isoenzyme CYP1A2.
    • $35
    In Stock
    Size
    QTY
  • Hydroxy Dimetridazole
    T37514936-05-0
    Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity. It was once widely used in the treatment of parasitic infections in poultry, cattle, swine and farmed fish until suspected to be carcinogenic and mutagenic to humans. Hydroxy dimetridazole is a metabolite of dimetridazole that may be useful for identifying this nitroimidazole in various agricultural samples through liquid chromatography-tandem mass spectrometry and other methods.
    • $59
    Backorder
    Size
    QTY
    TargetMol | Inhibitor Sale
  • N-Acetylprocainamide
    T024932795-44-1
    N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic drug.
    • $29
    In Stock
    Size
    QTY
  • Cycloguanil hydrochloride
    T5420152-53-4
    Cycloguanil hydrochloride (Chloroguanide Triazine) is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms, respectively).
    • $31
    In Stock
    Size
    QTY