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By Target- Topoisomerase
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Results for "
topo ii
" in TargetMol Product Catalog- Inhibitors & Agonists91
- PROTAC Products2
- Natural Products14
- Disease Modeling2
Doxorubicin hydrochloride
Cited
NSC 123127, Hydroxydaunorubicin hydrochloride, DOX hydrochloride, Adriamycin HCl
T102025316-40-9
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I II (IC50=0.8 2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitumor activity. Doxorubicin hydrochloride reduces the phosphorylation of AMPK and its downstream target protein acetyl coenzyme A carboxylase, and induces apoptosis and autophagy.
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CitedDoxorubicin Cited
Hydroxydaunorubicin, DOX, Adriamycin
T145623214-92-8
Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.
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