small molecule compounds

A unique collection of xnum kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.

A unique collection of xnum compounds targeting MAPK signaling for drug discovery in MAPK related diseases;

A unique collection of xnum cancer cell differentiation inducing compounds for high throughput and high content screening;

A unique collection of xnum bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification;

xnum small molecule compounds with pro-oxidant or anti-oxidant activity for high-throughput and high-content screening.

Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. In humans, oxidative stress is thought to be involved in the development of atherosclerosis, heart failure, myocardial infarction, cancer, infection etc. Antioxidants are a class of compounds that counteract oxidative stress and reduce oxidative damage. The TargetMol Antioxidant Compound Library is a unique collection of xnum small molecules with inhibitory effects on oxidative stress and is a useful tool for high-throughput screening and high-content screening in the study of oxidative stress.

A unique collection of xnum preclinical compounds for high throughput screening (HTS) and high content screening (HCS);

A unique collection of xnum clinical failed compounds for high throughput screening (HTS) and high content screening (HCS);

xnum methylation-related compounds that can be used for high-throughput and high-content screening.

TargetMol created the L4020 NO-PAINS Compound Library that applied the PAINS filter, remaining xnum small molecules that are suitable for new drug development, signaling pathway research, drug repurposing and other research.

A unique collection of xnum TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;

A unique collection of xnum Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;

A unique collection of xnum compounds with antibiotic activity for new antibacterial drug screening;

A unique collection of xnum anti-obesity compounds for high throughput and high content screening;

A unique collection of xnum calcium channel blockers and agonists for high throughput and high content screening;

A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;

A unique collection of xnum procoagulation and anticoagulation related compounds for high throughput screening (HTS) and high content screening (HCS);

A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;

A unique collection of xnum compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS);

A unique collection of xnum covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc.

The cysteine covalent library contains xnum compounds.

A unique collection of xnum endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);

A unique collection of xnum beta-lactam compounds, can be used in HTS and HCS;

A unique collection of xnum GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research;