ppl

PPL-100, a HIV protease inhibitor, is used potentially for the treatment of HIV infection.

Beta-Sitosterol (SKF 14463) has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Beta-Sitosterol (SKF 14463) , a main dietary phytosterol found in plants, may have the potential for prevention and therapy for human cancer. Although the exact mechanism of action of Beta-Sitosterol (SKF 14463) is unknown, it may be related to cholesterol metabolism or anti-inflammatory effects (via interference with prostaglandin metabolism). Beta-Sitosterol (SKF 14463) induces apoptosis and activates key caspases in MDA-MB-231 human breast cancer cells.

Monepantel (AAD1566) is an organic anthelmintic and nicotinic acetylcholine receptor antagonist from roundworms and esophagostomies that is widely used for de-worming in agriculture and livestock.

PL 100 could inhibit HIV-1 protease.

PPL agonist-1 (Compound I-3) is a highly selective agonist of Periplakin (PPL) that raises cAMP levels by modulating PPL, enhancing MITF expression, and consequently promoting melanin synthesis. Additionally, it stimulates melanin production by regulating tryptophan metabolism. Compared to Ruxolitinib, PPL agonist-1 demonstrates superior effectiveness and holds potential for vitiligo research.

VSPPLTLGQLLS, also known as peptide P3, is a small peptide that serves as an inhibitor of FGFR3, effectively suppressing FGFR3 phosphorylation. It hinders 9-cisRA-induced tracheal lymphangiogenesis and impedes lymphatic endothelial cell (LEC) activities, including proliferation, migration, and tubule formation [1] [2].

VSPPLTLGQLLS TFA, a small peptide FGFR3 inhibitor also known as peptide P3, effectively inhibits FGFR3 phosphorylation. It also prevents 9-cisRA-induced tracheal lymphangiogenesis and impedes lymphatic endothelial cell (LEC) proliferation, migration, and tubule formation [1] [2].

Ganoapplanoid F, a highly oxygenated lanostane triterpenoid derived from Ganoderma applanatum, impedes lipid accumulation in adipocytes and offers potential for obesity research [1].

Bovine Endothelial cell growth supplement is a medium additive that acts as an endothelial cell growth supplement (ECGS), enhancing the proliferation of human saphenous vein endothelial cells (HSVEC) and human umbilical vein endothelial cells (HUVEC).

Lp-PLA2-IN-3 is a potent, orally bioactive lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, effectively inhibiting recombinant human [Lp-PLA2] with an IC50 value of 14 nM.

YO-01027 (DBZ) is a potent γ-secretase inhibitor.

Iron(II) fumarate (Iron Fumarate) is the iron(II) salt of fumaric acid, a reddish-orange powder, applied to supply iron intake.

Benfotiamine (S-Benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1) employed as an antioxidant dietary supplement.

Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders.

Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.

L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) functions as an antioxidant and stimulates hepatocyte growth factor (HGF) production. This long-acting vitamin C derivative promotes collagen formation and expression.

L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) is utilized in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays.

Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.

Lanolin (wool wax)is a wax secreted by the sebaceous glandsofwool-bearing animals.

Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.

Buprofezin (Applaud) is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.

Ferrous Bisglycinate (Bisglycine iron(II) salt) is used in the fortification of infant formulations and foods.

Magnesium glycinate (magnesium 2-aminoacetate) is a supplement that boost magnesium levels in people with a deficiency of the mineral. Magnesium is a vital nutrient for regulating many body processes, including muscle and nerve function, blood sugar levels, and blood pressure. This mineral also supports the making of protein, bone, and DNA.

Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.