20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2137L | Pp60 c-src (521-533) (phosphorylated) acetate | Others | |
pp60 c-src (521-533) (phosphorylated) acetate is a regulator of focal adhesion formation and cell spreading. pp60 c-src (521-533) (phosphorylated) acetate also regulates cell motility and is a key component in the signal... | |||
T39185 | Pp60 (v-SRC) Autophosphorylation Site, Phosphorylated | pp60 (v-SRC) Autophosphorylation Site, Phosphorylated | |
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide derived from an EGFR substrate. It serves as a valuable tool for quantifying phosphorylated substrates in screening EGFR Kinase inhibitors... | |||
TP1590 | MARCKS Peptide(151-175), Phosphorylated | ||
Myristoylated Alanine-Rich C Kinase Substrate peptide (151-175) is a high affinity Protein Kinase C substrate. | |||
TP2137 | Pp60 c-src (521-533) (phosphorylated) | ||
Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potenti... | |||
T81578 | P60c-src substrate II, phosphorylated | ||
Phosphorylated p60c-src substrate II is a pentapeptide and a phosphorylated polypeptide form of p60c-src substrate II. Phosphorylation is a critical post-translational modification (post-translationmodification) vital fo... | |||
T3071 | Olverembatinib | GZD 824 | Bcr-Abl |
Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM). | |||
T7704 | KY-226 | Phosphatase | |
KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,) | |||
T2429 | Olverembatinib dimesylate | GZD824 Dimesylate,HQP1351 | Bcr-Abl |
Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I). | |||
T31929 | Giripladib | PLA 695,PLA-695,PLA695 | Phospholipase |
Giripladib (PLA695)(PLX-695) is a cPLA2-specific inhibitor that inhibits the radiation-induced increase of phosphorylated ERK and phosphorylated Akt in endothelial cells. | |||
TP1789L | Malantide acetate(86555-35-3 free base) | PKA , PKC | |
Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activ... | |||
T26078 | Rhodblock 6 | Rhodblock6,Rhodblock-6 | ROCK |
Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits the localization of phosphorylated MRLC (Myosin Regulatory Light Chain) and acts by specifically inhibiting Rho kinase activity. | |||
T67772 | Phos-tag Acrylamide AAL-107 | ||
Phos-tag Acrylamide AAL-107 is an acrylamide-pendant that can be used as a tool to visualize phosphorylated proteins. | |||
T5113 | L-GLUCOSE | L-(-)-Glucose | Others |
L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose is not bioavailable to cells as an energy source because it cannot be phosphorylated by hexokinase. | |||
T26193 | SKLB-163 | SKLB163 | MAPK , Akt , Caspase , Rho , JNK |
SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK. | |||
T17205 | UNC2541 | Others , FLT , TAM Receptor | |
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM). | |||
T5057 | DL-O-Phosphoserine | DL-2-Amino-3-hydroxypropanoic acid 3-phosphate,O-PHOSPHO-L-SERINE,DL-SOP | Others , Endogenous Metabolite |
DL-O-Phosphoserine (DL-SOP), a normal metabolite in human biofluid, is an ester of serine and phosphoric acid. Serine is one of three amino acid residues that are commonly phosphorylated by kinases during cell signaling ... | |||
T14569 | BI8626 | E1/E2/E3 Enzyme | |
BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZA... | |||
T3262 | Phosphocreatine disodium | Disodium phosphocreatine,Phosphocreatine disodium salt,Creatine phosphate disodium salt | Others , Endogenous Metabolite |
Phosphocreatine disodium (Phosphocreatine disodium salt) is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in muscle, skeletal, and brain. | |||
T6762 | AS1842856 | Autophagy , FOXO1 | |
AS1842856, a cell-permeable inhibitor, can block the transcription activity of Foxo1 (IC50: 33 nM). It can directly bind to the active Foxo1, but not the Ser256-phosphorylated form. | |||
T78473 | Sphingosine (d17:1) | C17 Sphingosine | |
Sphingosine (d17:1) (C17 Sphingosine) is a 17-carbon sphingolipid found in human skin that can be phosphorylated by sphingomyelin kinase.Sphingosine C-17 can be used as an internal standard to perform spectroscopic analy... |