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Cat No. | Product Name | Synonyms | Targets |
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T4188 | SDZ285428 | SDZ285-428 | P450 , Parasite , Antifungal |
SDZ285428 is a CYP24A1 inhibitor. | |||
T0849 | Pyrimethamine | Pirimecidan,RP 4753,Pirimetamin | DHFR , Antifolate , Parasite |
Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug. | |||
T2279 | Tizoxanide | Desacetyl-nitazoxanide,TIZ | Antiviral , HIV Protease , Antibacterial , Autophagy |
Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). | |||
T15173 | DSM265 | Others | |
DSM265 is a long-duration P. falciparum dihydroorotate dehydrogenase inhibitor (IC50: 8.9 nM). DSM265 can also inhibit the growth of Pf3D7 parasites (EC50: 4.3 nM). | |||
T1061 | Toltrazuril | BAY-i 9142,Toltrazurilo,Baycox,Toltrazurilum | Antibiotic , Parasite |
Toltrazuril (Toltrazurilo), an antiprotozoal agent, has effect on Coccidia parasites. | |||
T7744 | Piperaquine tetraphosphate tetrahydrate | Parasite | |
Piperaquine tetraphosphate tetrahydrate is a potent anti-parasites agent. | |||
T0390 | Aklomide | Alkomide,2-Chloro-4-nitrobenzamide | Antibiotic , Parasite |
Aklomide (2-Chloro-4-nitrobenzamide) is used in poultry to treat parasites. | |||
T20812 | Azamethiphos | AChE | |
Azamethiphos, an organothiophosphate insecticide, is used in Atlantic salmon fish farming to control parasites. | |||
T6607 | Nitenpyram | Niterndipoine,Bestguard,Capstar | AChR |
Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets. | |||
T37072 | Nitroxynil | 4-Hydroxy-3-iodo-5-nitrobenzonitrile,Trodax,Dovenix | Parasite |
Nitroxynil (4-Hydroxy-3-iodo-5-nitrobenzonitrile) is an anthelmintic compound that effectively targets parasites in both adult and immature stages. It is extensively employed in investigations pertaining to Fasciola hepa... | |||
T5052 | Toltrazuril (sulfone) | Toltrazuril sulfone,Ponazuril | Parasite |
Toltrazuril sulfone (Ponazuril) is an antiprotozoal agent that acts upon Coccidia parasites. | |||
T3361 | Cambendazole | Bonlam,MK-905,Novazole | Others |
Cambendazole (Novazole) is one of the most effective agents for the therapy of human strongyloidiasis. Cambendazole is a nematocide effective against a variety of gastrointestinal parasites in cattle, sheep, and horses. | |||
T0951 | Hydroxychloroquine sulfate | Acidum iopanoicum,HCQ sulfate | DNA , SARS-CoV , TLR , Parasite , Autophagy |
Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in ... | |||
T28824 | SNX0723 | SNX 0723,SNX- 0723 | HSP |
SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respectively. SNX0723 inhibits liver-stage P. berghei ANKA parasit... | |||
T9549 | Chiniofon | Loretin,Ferron,8-hydroxy-7-iodo-5-quinolinesulfonate,quiniophen | Others |
Chiniofon (Ferron), a halogenated 8-hydroxyquinoline, is used as an antiamebic drug. This type of anti-amebic drug exerts an anti-amebic effect by inhibiting intestinal commensal bacteria and affects amoebic dysentery, b... | |||
T33690 | Nitroscanate | Lopatol,CGA-23654GS,CGA 23654 | |
Nitroscanate is an anthelmintic found to be effective in certain strains of parasites in canines. | |||
T38729 | Melarsonyl dipotassium | Melarsonic acid dipotassium | |
Melarsonyl dipotassium, also known as melarsonic acid dipotassium, is a potent anthelmintic agent with the ability to effectively inhibit parasites. | |||
T71841 | MMV085203 | ||
MMV08520 is a novel inhibitor of Plasmodium falciparum, killing both blood- and sexual-stage P. falciparum parasites. | |||
T70673 | NEU617 | ||
NEU617 is an inhibitor of the growth of protozoan parasites, against T. brucei bloodstream proliferation. | |||
T14780 | BRD9185 | Dehydrogenase | |
BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro. | |||
T10328 | Anti-parasitic agent 3 | Others | |
Anti-parasitic agent 3 is an anti-parasitic agent active against drug-resistant parasites. | |||
T27400 | Ganaplacide | KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156 | |
Ganaplacide is an antimalarials with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites. KAF156 showed antimalarial activity without evident safety concerns in a s... | |||
T70507 | KAI-407 | ||
KAI407 is a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. KAI407 showed an activity profile similar to that of primaquine (PQ), efficiently killing th... | |||
T37639 | Toltrazuril sulfoxide | ||
Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril , and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Cocc... | |||
T40087 | DSM502 | ||
DSM502, a pyrrole-based Dihydroorotate Dehydrogenase (DHODH) inhibitor, demonstrates potent nanomolar activity against Plasmodium DHODH and Plasmodium parasites, while not inhibiting mammalian DHODHs. | |||
T40291 | DSM705 | DSM705 | |
DSM705 is a pyrrole-based inhibitor of Dihydroorotate Dehydrogenase (DHODH). It demonstrates high potency in the nanomolar range against Plasmodium DHODH and Plasmodium parasites, while not interfering with mammalian DHO... | |||
T28937 | Tebuquine | WR-228,258,WR 228,258,CI 897,CI897,CI-897 | |
Tebuquine is an antimalarial agent. Tebuquine is active against P. falciparum in vitro. Tebuquine in vitro shows a chloroquine-like effect, but not in vivo, suggesting that its mode of action in vivo is different from th... | |||
T72547 | Plm IV inhibitor-2 | ||
Plm IV inhibitor-2 is a potent digestive vacuole plasmepsins IV ( Plm IV ) inhibitor with IC 50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria cau... | |||
T35740 | FR900098 (sodium salt) | ||
FR900098 is a derivative of fosmidomycin that has antimalarial activity (IC50s = 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively). FR900098 inhibits DOXP reductoisomerase, a key enzyme in the... | |||
T39256 | MMV674850 | MMV674850 | |
MMV674850 exhibits potency against asexual stage parasites, with IC50 values of 2.7 and 4.5 nM. Furthermore, it demonstrates a preferential affinity for early-stage gametocytes, displaying an IC50 value of 4.5 ± 3.6 nM, ... | |||
T75331 | Brilliant green | ||
Brilliant green is a cationic dye used to color silk and wool. Brilliant green inhibits propagation of mold, intestinal parasites and fungus . Brilliant green is effective against Gram-positive bacteria [1] [2] . | |||
T62550 | DSM705 hydrochloride | ||
DSM705 hydrochloride is a potent antimalarial compound and a pyrrole-based inhibitor of dihydroorotate dehydrogenase (DHODH).DSM705 hydrochloride shows nanomolar effects against PlasmodiumDHODH and Plasmodium parasites a... | |||
T79471 | Antileishmanial agent-20 | Parasite | |
Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L. infantum and 0.2 μM for L. braziliensis. It is a potential research tool for studying these parasites [1]. | |||
T62362 | GNF6702 | ||
GNF6702 is a selective inhibitor of the kinetoplastid proteasome and has been shown to be effective against parasites in mouse models of leishmaniasis, Chagas disease and human African trypanosomiasis. | |||
T61917 | TCMDC-125457 | ||
TCMDC-125457 can effectively induce calcium redistribution, but has little effect on inhibiting heme crystallization. When TCMDC-125457 is combined with artesunate, it can effectively treat tightly synchronized artemisin... | |||
T74934 | Trypanothione synthetase-IN-3 | ||
Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor ( K i : 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum [1] . | |||
T12250 | NPD-1335 | Others | |
NPD1335 is a potent Trypanosoma brucei phosphodiesterase B1 ( TbrPDEB1 ) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 shows a greatly improved cytotoxicity profile. NPD1335 increases intra... | |||
T35732 | Diacetylcercosporin | ||
Diacetylcercosporin is a perylenequinone produced by Cercospora and Septoria that has diverse biological activities. It inhibits the growth of P. falciparum strains that are sensitive and resistant to chloroquine and L. ... | |||
T62677 | Ganaplacide hydrochloride | ||
Ganaplacide (KAF156) hydrochloride is a first-of-its-kind, orally active imidazolopiperazine antimalarial drug.Ganaplacide hydrochloride is active against a wide range of Plasmodium species, including drug-resistant para... | |||
T75536 | Koshidacin B | ||
Koshidacin B, a cyclic tetrapeptide, exhibits potent antiplasmodial activity, evidenced by its ability to inhibit Plasmodium falciparum strains FCR3 and K1 with IC50 values of 0.89 μM and 0.83 μM, respectively. It has be... | |||
T38269 | Purfalcamine | ||
Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes mala... | |||
T79277 | Cysteine protease inhibitor-3 | Parasite | |
Cysteine protease inhibitor-3 (Compound 15), a cysteine protease inhibitor, exhibits anti-plasmodial activity, effectively inhibiting Pf3D7 (IC50 = 0.74 μM), PfW2 (IC50 = 1.05 μM), PfFP2 (IC50 = 3.5 μM), and PfFP3 (IC50 ... | |||
T9763 | MMV666810 | ||
MMV666810, a 2-aminopyrazine similar to MMV390048, is potent against asexual parasites at 5.94 nM. MMV666810 is more active on late-stage gametocytes, it has a 3.3-fold selectivity to late-stage gametocytes compared to e... | |||
T75338 | Acridine Orange base | ||
Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells... | |||
T74247 | TPE-MI | ||
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells. TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington dise... | |||
T65396 | Piperazine 2HCl | ||
Piperazine (2HCl) is gamma-aminobutyric acid (GABA) agonists and its major effects appear to be on the central nervous system. Piperazine was the anthelmintic with the greatest number of reports of toxicoses and suspecte... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN6730 | Epoxyazadiradione | NF-κB | |
Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NF-kB in human cervical cancer cells. | |||
T13539 | Allopurinol riboside | Others , Endogenous Metabolite , Parasite , Drug Metabolite | |
Allopurinol riboside is a metabolite of allopurinol with potency against parasites. Allopurinol riboside competitively inhibits the action of purine nucleoside phosphorylase on inosine with a Ki of 277 μM. | |||
TN4883 | Quinine sulfate dihydrate | Others | |
Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassiu... | |||
T13753 | (±)-Licarin A | (±)-trans-Dehydrodiisoeugenol | Others |
(±)-Licarin A ((±)-trans-Dehydrodiisoeugenol) is a dihydrobenzofuran neolignan, the resultant of an oxidative coupling reaction of isoeugenol and horseradish peroxidase (HRP) enzyme. (±)-Licarin A shows 100% parasites mo... | |||
TN1442 | Betulinic acid methyl ester | Antifection | |
Betulinic acid methyl ester showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro.It also inhibited B16 2F2 cell proliferation by induction of apoptosis. | |||
T75617 | Salviandulin E | ||
Salviandulin E is a diterpenoid compound that can be isolated from Salvia leucantha CAV.. Salviandulin E shows antitrypanosomal activity against T. b. brucei GUTat 3.1 parasites with an IC 50 value of 0.72 µg/mL [1] [2] ... | |||
T16381 | Okadaic acid | Others | |
Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A, and PP3 inhibitor (IC50s: 10-15 nM, 0.5 nM, and 4 nM, respectively). Okadaic acid is extracted fr... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04180 | PfLDH Protein, P. falciparum, Recombinant (His) | P. falciparum | E. coli |
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR as... | |||
TMPY-02929 | ENTPD2 Protein, Human, Recombinant (aa 29-460, His) | Human | Baculovirus-Insect Cells |
NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; ... | |||
TMPY-05220 | TSLP Protein, Human, Recombinant (R127A & R130S, His) | Human | HEK293 |
Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ... | |||
TMPY-05453 | TSLP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ... | |||
TMPY-02428 | TSLP Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ... | |||
TMPY-00638 | Interferon alpha B/IFNA8 Protein, Human, Recombinant (His) | Human | HEK293 |
Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites... | |||
TMPY-04578 | Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) | Human | Yeast |
IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, par... | |||
TMPY-03467 | IFN-beta Protein, Mouse, Recombinant | Mouse | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPY-00831 | IFN-beta Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPY-03145 | IFN-beta Protein, Human, Recombinant | Human | CHO |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPK-00255 | CD209/DC-SIGN Protein, Human, Recombinant (His) | Human | HEK293 |
C-type lectin CD209/DC-SIGN and CD209L/L-SIGN proteins are distinct cell adhesion and pathogen recognition receptors that mediate cellular interactions and recognize a wide range of pathogens, including viruses such as S... | |||
TMPH-03296 | Galectin-3/LGALS3 Protein, Rat, Recombinant (His) | Rat | E. coli |
Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group.; The cysteine protease may... | |||
TMPH-02163 | Syncytin-1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU). DNA base J is a hypermodified thymidine residue found in the genome o... | |||
TMPY-06505 | TSLP Protein, Human, Recombinant (hFc) | Human | HEK293 |
Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ... | |||
TMPY-05756 | TSLP Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ... | |||
TMPY-04765 | PKLR Protein, Human, Recombinant (His) | Human | E. coli |
Pyruvate kinase (PKLR) is a critical erythrocyte enzyme that is required for glycolysis and production of ATP. Pyruvate kinase deficiency (PKD) is the most frequent red blood cell enzyme abnormality of the glycolytic pat... | |||
TMPY-03648 | Interferon alpha B/IFNA8 Protein, Human, Recombinant | Human | HEK293 |
Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites... | |||
TMPY-03620 | Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (mFc) | Cynomolgus | HEK293 |
Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites... | |||
TMPY-03637 | Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites... | |||
TMPY-02865 | Interferon alpha 1/IFNA1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, par... | |||
TMPH-00903 | Human adenovirus F serotype 40 Hexon protein (His & Myc) | HAdV-40 | E. coli |
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine se... | |||
TMPY-02743 | Interferon alpha 1/IFNA1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, par... | |||
TMPY-04634 | Interferon alpha 1/IFNA1 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, par... | |||
TMPH-02271 | BTK Protein, Human, Recombinant (His) | Human | Baculovirus |
Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ... | |||
TMPY-02456 | IFN-beta Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPY-03828 | IFN-beta Protein, Rhesus, Recombinant (mFc) | Rhesus | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... |
Cat No. | Product Name | ||
---|---|---|---|
L6620 | Antiparasitic Natural Product Library | 253 compounds | |
A unique collection of 253 natural products with antiparasitic activity, a powerful tool for high throughput screening (HTS) and high content screening (HCS); | |||
L1800 | Anti-Infection Compound Library | 2977 compounds | |
A unique collection of 2977 anti-infective compounds including anti-bacterial, anti-fungi, anti-Human Cytomegalovirus (HCMV), anti-HIV, anti-SARS, anti-influenza, etc; | |||
L6610 | Anti-infective Natural Product Library | 1070 compounds | |
A unique collection of 1070 species of natural products with anti-infective activity for high throughput screening (HTS) and high content screening (HCS); |