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Results for "

irf3

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    25
    TargetMol | Inhibitors_Agonists
  • Dye Reagents
    1
    TargetMol | Dye_Reagents
  • Natural Products
    2
    TargetMol | Natural_Products
  • Recombinant Protein
    15
    TargetMol | Recombinant_Protein
  • Antibody Products
    12
    TargetMol | Antibody_Products
TargetMolTargetMolCompare
IRF3 Protein, Mouse, Recombinant (His & Myc)
IRF-3, Irf3, Interferon regulatory factor 3
TMPH-02734
Expression system: P. pastoris (Yeast)
Length: 1-419, Full Length
Activity: Not Tested
  • Inquiry Price
20 days
Size
QTY
Buffer-exchangeable
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IRF3 Protein, Human, Recombinant (His)
IRF-3, IRF3, Interferon regulatory factor 3
TMPH-04626
IRF3 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is Q14653.
  • Inquiry Price
20 days
Size
QTY
SPR-compatible buffer
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TRAIP Protein, Human, Recombinant (His)
TRIP, TRAIP, TRAF-interacting protein, RNF206, RING finger protein 206, E3 ubiquitin-protein ligase TRAIP
TMPH-01270
Expression system: E. coli
Length: 1-469, Full Length
Activity: Not Tested
  • Inquiry Price
20 days
Size
QTY
Buffer-exchangeable
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Influenza A H1N1 (strain A/Malaysia:Malaya/302/1954) Non-structural protein 1 (His & Myc)
NS1A, NS1, NS, Non-structural protein 1
TMPH-02349
Expression system: E. coli
Length: 1-237, Full Length
Activity: Not Tested
  • Inquiry Price
20 days
Size
QTY
Buffer-exchangeable
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Zaire ebolavirus (strain Kikwit-95) VP35 Protein (E. col, His & Myc)
VP35, Polymerase cofactor VP35, Ebola VP35 (eVP35)
TMPH-03732
Expression system: E. coli
Length: 1-340, Full Length
Activity: Not Tested
  • Inquiry Price
20 days
Size
QTY
Buffer-exchangeable
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Zaire ebolavirus (strain Kikwit-95) VP35 Protein (His & Myc)
VP35, Polymerase cofactor VP35, Ebola VP35 (eVP35)
TMPH-03733
Expression system: HEK293 Cells
Length: 1-340, Full Length
Activity: Not Tested
  • Inquiry Price
20 days
Size
QTY
Buffer-exchangeable
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Sting Protein, Human, Recombinant (Sumo & His)
TMEM173, sting, Stimulator of interferon genes protein, Mediator of IRF3 activation
TMPJ-01206
Expression system: E. coli
Length: 155-341, Partial
Activity: Not Tested
  • Inquiry Price
7-10 days
Size
QTY
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ZBP1 Protein, Human, Recombinant (His)
Z-DNA-Binding Protein 1, ZBP1, Tumor Stroma and Activated Macrophage Protein DLM, DLM1, C20orf183
TMPJ-01328
Expression system: E. coli
Length: 1-149, Partial
Activity: Not Tested
  • Inquiry Price
7-10 days
Size
QTY
SPR-compatible buffer
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SARS-CoV-2 Papain-Like Protease Protein
Replicase polyprotein 1a, pp1a, PL-PRO, PLpro, Papain-like Protease
TMPJ-01431
Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro). These proteases are important targets for development of antiviral drugs that would inhibit viral replication and reduce mortality associated with outbreaks of SARS-CoV. PLpro is a cysteine protease located within the non-structural protein 3 (NS3) section of the viral polypeptide. PLPro activity is required to process the viral polyprotein into functional, mature subunits; specifically, PLPro cleaves a site at the amino-terminus of the viral replicase region. In addition to its role in viral protein maturation, PLPro possesses a deubiquitinating and deISGylating activity. In vivo, this protease antagonizes innate immunity by inhibiting IRF3-induced production of type I interferons.
  • Inquiry Price
7-10 days
Size
QTY
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Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)
NS3
TMPY-00323
HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B. HCV NS3 RNA helicase binds to RNA and unwinds dsRNA in the 3' to 5' direction, and likely RNA stable secondary structure in the template strand (By similarity). Cleaves and inhibits the host antiviral protein MAVS. NS3 NS4A complex also prevents phosphorylation of human IRF3, thus preventing the establishment of dsRNA induced antiviral state. One of the HCV proteases, NS3-4A serine protease, is a non-covalent heterodimer consisting of a catalytic subunit (the N-terminal one-third of NS3 protein) and an activating cofactor (NS4A protein) and is responsible for cleavage at four sites of the HCV polyprotein.
  • Inquiry Price
7-10 days
Size
QTY