20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10850 | CMP-5 | Antiviral , Histone Methyltransferase | |
CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection. | |||
T10851 | CMP-Sialic acid sodium salt | CMP-Neu5Ac sodium salt | Others |
CMP-Sialic acid sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. It provides a substrate for Golgi sialyltransferases. UDP-GlcNAc 2-epimerase initiates sialic acid synthesis. | |||
T10850L | CMP-5 2HCl | Others | |
CMP-5 2HCl is a anthelmintic agent. CMP-5 2HCl shows EC100 of 5μM against H. contortus in vitro. | |||
T19243 | CMP-5 hydrochloride | Others | |
CMP-5 hydrochloride is a potent and selective PRMT5 inhibitor, while displays no activity against PRMT1/4/7 enzymes. It selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. | |||
T1591 | Ancitabine hydrochloride | NSC 145668 HCl,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C | Others , DNA/RNA Synthesis , Autophagy |
Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytar... | |||
TMO2752 | Cytidine 5'-monophosphate | 5'-Cytidylic acid,5'-CMP,Cytidylic Acid | Others , Endogenous Metabolite |
Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide, one of the basic units that make up RNA. It consists of nucleobase cytosine, pentose ribose and phosphate groups. | |||
T83629 | Smurf-1 modulator CMP Example 20 | Smurf-1-IN-20 | Others |
Smurf-1 modulator CMP Example 20 (Smurf-1-IN-20) is a potent Smurf-1 modulator. | |||
T14987 | CMP8 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, res... | |||
T27606 | Indantadol HCl | CHF-3381,CMP-3381,GT-3381,V-3381,CNP-3381,Indantadol | MAO , NMDAR |
Indantadol HCl (CHF-3381) is a NMDA antagonist and nonselective MAO inhibitor. | |||
T3080 | Pyridone 6 | Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,JAK Inhibitor I | Tyrosine Kinases , JAK |
Pyridone 6 (JAK Inhibitor)(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM... | |||
T73747 | CMP-Sialic acid | ||
CMP-Sialic acid (CMP-Neu5Ac) serves as an allosteric inhibitor of UDP-GlcNAc 2-epimerase, a substrate for Golgi sialyltransferases, and is crucial for the biosynthesis of sialic acid and its conjugates [1]. | |||
T27052 | CMP3a | CMP-3a,CMP 3a | |
CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destab... | |||
T39750 | CMP98 | ||
CMP98, a proteolysis targeting chimera (PROTAC), exhibits a lack of VHL degradation efficacy. It can function as a negative control compound in comparison to CM11. CMP98 comprises two von Hippel-Lindau ligands operating ... | |||
T40426 | Cytidine 5'-diphosphate trisodium salt | CDP | Others |
Cytidine 5'-diphosphate trisodium salt (CDP) can produce Cytidine triphosphate for synthesis of DNA and RNA through the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosp... | |||
T68490 | CMPF | Microtubule Associated | |
CMPF is a microtubule protein inhibitor that can be used to study tumors. | |||
T14989 | CMPD101 | ROCK , GRK , PKC | |
CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with I... | |||
T14988 | CMPD1 | MAPK | |
CMPD1 is a non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor(apparent Ki (Kiapp): 330 nM). | |||
T25267 | Cmpd 339509 | Cmpd339509,Cmpd-339509 | |
Cmpd 339509 is a DprE1 inhibitor. DprE1 is an epimerase required for cell wall biosynthesis. | |||
TQ0114 | CMPDA | GluR | |
CMPDA is a positive allosteric modulator of AMPA receptors (EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor). | |||
T70628 | Cmpd-A | ||
Cmpd-A is a time-dependent CENP-E inhibitor with potent antitumor activity. Cmpd-A inhibits the ATPase activity of the CENP-E motor domain, acting as a time-dependent inhibitor with an ATP-competitive-like behavior. Cmpd... |