triazole

MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).

Voriconazole (UK-109496) is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 [CYP3A].

Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes necessary for ERGOSTEROL synthesis.

Fluconazole (UK-49858) belongs to the triazole class of antifungal agents and is a CYP51 inhibitor (IC99 = 0.20–0.39 μg/mL against Candida albicans), possessing broad-spectrum antifungal activity, good oral absorption, and cell permeability. This compound is used for the treatment of various invasive fungal infections.

Isavuconazole (RO-0094815)(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557 with MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata.

Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonist

Triticonazole is a triazole pesticide and fungicide. Triticonazole shows endocrine disrupting activities.

1,2,4-Triazole ,with CAS No. 288-88-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1,2,4-Triazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3,5-Diphenyl-4H-1,2,4-triazole, with CAS No. 2039-06-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3,5-Diphenyl-4H-1,2,4-triazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-(2-HYDROXYETHYL)-1,2,4-TRIAZOLE, with CAS No. 3273-14-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-(2-HYDROXYETHYL)-1,2,4-TRIAZOLE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double-cleavable PEG linker (3-unit and 4-unit) designed for antibody-drug conjugation (ADC).

Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide is a drug-linker conjugate for ADCs (antibody-drug conjugates). It consists of Triptolide coupled with a stable, cleavable linker [Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-Cl]. This compound is utilized in the synthesis of antibody-drug conjugates (ADCs).

Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-Cl is a cleavable silicon ether-based ADC linker utilized in the synthesis of antibody-drug conjugates (ADC).

Methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66475 and the CAS number is 217448-86-7.

1-Methyl-1,2,4-triazole is a useful organic compound for research related to life sciences. The catalog number is T67137 and the CAS number is 6086-21-1.

1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate is a useful organic compound for research related to life sciences. The catalog number is T67318 and the CAS number is 86386-77-8.

Ethyl 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T67440 and the CAS number is 361990-21-8.

4-Phenyl-1H-1,2,3-triazole, an inhibitor of the enzyme IDO1 (IC50: 60 µM), is utilized in cancer research [1].

3-phenyl-2H-1,2,4-triazole, with CAS No. 3357-42-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-phenyl-2H-1,2,4-triazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Methyl 1-β-D-ribofuranosyl-1H-1,2,4-triazole-3-carboxylate is a reagent used in biochemical reactions.

1-β-D-2'-Deoxyribofuranosyl-1,2,4-triazole-3-carboxamide-5'-O-triphosphate (tetrasodium) is a nucleotide analog. It can be utilized in research involving the Sequence Saturation Mutagenesis (SeSaM) technique.

Methyl 1H-1,2,4-triazole-5-carboxylate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

3-Mercapto-1,2,4-triazole is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide serves as an ADC linker, utilized in the synthesis of antibody-drug conjugates (ADCs). This compound is a click chemistry reagent, featuring a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups.