tnfsf 2

TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 18.35 kDa and the accession number is P79337.

TNF alpha Protein, Ferret, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.88 kDa and the accession number is A3FBF1.

Expression system: HEK293 Cells
Length: 77-233, Partial
Activity: ELISA、SPR

Expression system: HEK293 Cells
Length: 77-233, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 77-233, Partial
Activity: Cell Activity

Expression system: E. coli
Length: 77-233, Partial
Activity: Not Tested

Expression system: E. coli
Length: 80-235, Partial
Activity: Not Tested

Expression system: E. coli
Length: 57-233, Extracellular Domain
Activity: BLI、Cells

Expression system: E. coli
Length: 77-233, Partial
Activity: SPR、Cells

Expression system: E. coli
Length: 78-235, Partial
Activity: Not Tested

Expression system: E. coli
Length: 77-233, Partial
Activity: Cell Activity

Expression system: E. coli
Length: 80-235, soluble form
Activity: Cell Activity

TNF alpha Protein, Rat, Recombinant (Yeast) is expressed in P. pastoris (Yeast). The accession number is P06804.

TNF alpha Protein, Bovine, Recombinant is expressed in E. coli. The accession number is Q06599.

TNF alpha Protein, Porcine, Recombinant is expressed in E. coli. The accession number is P23563.

RANKL TNFSF11 CD254 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 52.4 kDa and the accession number is AAC51762.1.

RANKL TNFSF11 CD254 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the accession number is AAC51762.1.

The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R. APRIL TNFSF13 Trimer Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 49.9 kDa and the accession number is O75888-1.

Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL TNFSF11 CD254 Protein, Human, Recombinant (aa 63-244) is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is O14788-2.

RANKL TNFSF11 CD254 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is AAC51762.1.

The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFFR.

Expression system: HEK293 Cells
Length: 96-241, Full Length of Mature Protein
Activity: ELISA

APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R. APRIL binds to heparan sulfate proteoglycans (HSPGs) independently of its binding to TACI and BCMA. APRIL can form bioactive heterotrimers with BAFF, and these circulate in the serum of patients with rheumatic immune disorders. APRIL enhances the proliferation and survival of plasma cells and also promotes T cell-dependent humoral responses. APRIL levels are elevated in the serum during coronary artery disease, and it is also elevated in many cancers primarily due to expression by tumor-infiltratin neutrophils.

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5. The activation of the TRAIL pathway in inducing tumor-selective apoptosis leads to the development of TRAIL-based cancer therapies, which include recombinant forms of TRAIL, TRAIL receptor agonists, and other therapeutic agents.