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BCH001 is a specific small-molecule inhibitor of PAPD5.

Sterculic acid, a stearoyl-CoA desaturase-1 (SCD1) inhibitor, effectively suppresses delta-9 desaturase (Δ9D) activity in a dose-dependent manner, exhibiting an inhibition concentration (IC50) value of 0.9 μM [1].

Terconazole (Terazol 7) is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and promoting loss of essential intracellular elements. Terconazole is active against Candida sp.

Terciprazine is a piperazine analog, antipsychotic drug.

Terchebulin is a useful organic compound for research related to life sciences. The catalog number is T126044 and the CAS number is 132854-40-1.

Stercobilin hydrochloride (mixture of isomers) is a bile pigment metabolized by intestinal bacteria and also acts as an inhibitor of HIV protease (HIVProtease) with a Ki of 4 μM. This compound can induce pro-inflammatory activity in mouse macrophage RAW264 cells, including the production of TNF-α and IL-1β. Stercobilin hydrochloride (mixture of isomers) is utilized in research on inflammation and viral infections.

Stercuronium is an aminosteroid neuromuscular blocking agent which was never marketed. It acts as a competitive antagonist of the nicotinic acetylcholine receptor, and is also reported to be an acetylcholinesterase inhibitor.

Luspatercept (ACE-536), a recombinant modified ActRIIB fusion protein, selectively binds to transforming growth factor β superfamily ligands, thereby enhancing erythrocyte production and advancing the maturation of erythroid precursors. Moreover, by binding with GDF11, it inhibits Smad2/3 signaling. This compound is instrumental in anemia research [1].

Sterculic acid methyl ester, an ester derivative of sterculic acid known for inhibiting Δ9 desaturase, has been found to adversely affect and exhibit toxicity towards R. opacus bacteria at a concentration of 0.75 mM. It not only hampers bacterial growth but also modifies fatty acid composition by reducing stearate and oleate levels, increasing the palmitate ratio, and decreasing overall fatty acid content at 0.25 or 0.5 mM concentrations. Additionally, at 50 ppm, Sterculic acid methyl ester enhances the tumor growth-promoting effects of aflatoxin Q1 in rainbow trout, indicating a synergistic interaction between the two compounds. [Matreya, LLC. Catalog No. 1236]

Ditercalinium chloride, an anticancer agent, inhibits human DNA polymerase gamma activity and can deplete mitochondrial DNA in both mouse and human cells. Additionally, Ditercalinium chloride is a potential ligand against the COMMD10-AP3S1 fusion protein [1] [2].

Cibotercept is a monoclonal antibody targeting MSTN, INHBA, and GDF11.

Elritercept (KER-050) is a recombinant fusion protein composed of a modified extracellular domain of the activin receptor type IIA fused to human IgG1 Fc. It functions by inhibiting activin A and other specific ligands of the TGF-β superfamily.

Rinvatercept is a fusion protein composed of sequences from the extracellular domains of human ACVR2A/B, forming a glycyl (1)-chimeric N-terminus (1-108)-peptide (2-109), and linked with the Fc fragment of immunoglobulin G1 (IgG1) via a G3 peptide linker (110-112). It is applicable in neuromuscular disease research.

Stercobilinogen is a microbial metabolite of bilirubin found in the intestines. It is utilized in metabolic research.

Exo-β-1,4-xylosidase, derived from Clostridium stercorarium (EC.3.2.1.37), is an exonuclease that specifically targets the β-1,4 glycosidic bonds at the non-reducing ends of xylan and xylooligosaccharides. This enzyme requires Ca2+ ions, facilitating the hydrolysis of β-1,4 glycosidic bonds through reversible metal ion binding, consequently breaking down xylan into xylose. It is utilized in fields such as lignocellulosic bioconversion, bioethanol production, and the optimization of xylan saccharification processes.

20-HC-Me-Pyrrolidine is a potent Aster protein inhibitor with IC50=0.06~0.71 μm for Aster-A, Aster-B, and Aster-C that blocks the ability of Aster proteins to bind and transfer cholesterol, including inhibiting the movement of LDL cholesterol to the endoplasmic reticulum.

Demeclocycline (Declostatin) is a tetracycline antibiotic produced by a strain of Streptomyces aureofaciens.Demeclocycline has antimicrobial activity and inhibits the action of vasopressin on the renal tubules, leading to diuresis. Demeclocycline can be used to induce diuresis and acute renal failure.

Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits APE1 via direct protein binding(KD: 10 nM).

KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.

TY-51469 is an inhibitor of chymase (IC50s for simian and human chymases: 0.4 and 7.0 nM, respectively).

BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.

Pixantrone dimaleate (Pixantrone Maleate) (BBR 2778 dimaleate) is an experimental antineoplastic drug.

m-Hydroxy-allyl ester carbanilic acid is a bioactive chemical.

Arachidonoyl-L-carnitine chloride is an endogenous metabolite and acylcarnitine widely used in biochemical experiments and studies of metabolic disorders.