Search Result

Search Results for " leukemic "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T8839	ICCB280		Apoptosis , Others
	ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome resistance to other current therapies for AML with an unfavo...		Apoptosis , Others
T6641	Rilmenidine Phosphate		Apoptosis , Adrenergic Receptor , Autophagy , Imidazoline Receptor
	Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.
T3278	Piribedil	EU-4200,Trivastan,ET-495,Trivastal	Dopamine Receptor , Histone Methyltransferase , Adrenergic Receptor
	Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
T12575	Unesbulin	PTC596	Apoptosis , BMI-1
	Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).		Apoptosis , BMI-1
T8531	M-3M3FBS		Apoptosis , Phospholipase
	m-3M3FBS is a phospholipase C (PLC) activator.		Apoptosis , Phospholipase
T4215	TCS-PIM-1-4a	SMI-4a	Apoptosis , Pim
	TCS-PIM-1-4a (SMI-4a), a Pim inhibitor, blocks mTORC1 activity through activation of AMPK and kills a wide range of both myeloid and lymphoid cell lines (IC50=0.8-40 μM).		Apoptosis , Pim
T11766L	Eltanexor	ONO-7706,KPT-8602,ATG-016	Others
	Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes ...		Others
T14550	BETd-260	ZBC 260	Epigenetic Reader Domain
	BETd-260, a PROTAC linked by a Cereblon ligand and a BET ligand, has an inhibitory effect on BRD4 protein in leukemic cell lines.		Epigenetic Reader Domain
T15337	Forodesine	BCX-1777,Immucillin-H	Others
	Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine is an orally active inhibitor of purine nucleoside phosphorylase (IC50s: 0.48 to 1.57 nM for human, mouse, rat, monkey, and dog PNP). It could i...		Others
T64338	AKI603	AKI 603,AKI-603	Aurora Kinase
	AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in l...		Aurora Kinase
T9428	HM43239		FLT
	HM43239 is an orally active and selective FLT3 inhibitor with IC 50 s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. HM43239 directly inhibits the k...		FLT
T68736	KU-0058948
	KU-0058948 is a poly (ADP-ribose) polymerase (PARP) inhibitor that induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro.
T82583	Deoxyharringtonine
	Deoxyharringtonine, an alkaloid extracted from the Cephalotaxus genus, exhibits significant anti-leukemic properties [1].
T38718	Cytarabine triphosphate	Cytarabine triphosphate,Ara-CTP
	Cytarabine triphosphate (Ara-CTP), a competitive inhibitor of DNA synthesis and an active metabolite of Cytarabine, exhibits predictive potential for leukemic blasts' chemosensitivity to Cytarabine through intracellular ...
T39861	AS-85
	AS-85, a potent inhibitor of ASH1L histone methyltransferase (IC50 = 0.6 μM), exhibits anti-leukemic activity by strongly binding to the ASH1L SET domain (Kd = 0.78 μM).
T22104	ML-291
	ML291 is a sufonamidebenzamide compound that induces the unfolded protein response (UPR) and overwhelms the adaptive capacity of UPR, resulting in apoptosis in various solid cancer models. It activates the PERK/eIF2a/CHO...
T41205	3',3'-cGAMP sodium salt
	3',3'-cGAMP sodium salt is a STING agonist. Reduces B cell proliferation and induces apoptosis of malignant B cellsin vitro. Suppresses 5TGM1 multiple myeloma xenograft growth in immunodeficient mice, and induces leukemi...
T61858	HDAC8-IN-3
	HDAC8-IN-3 (compound P19) is a highly potent inhibitor of HDAC8, displaying an IC50 value of 9.3 μM and producing thermal stabilization. Moreover, HDAC8-IN-3 exhibits cytotoxicity and induces apoptosis specifically in le...
T23975	Deacylcortivazol	UNII-3JO09QT49F,DAC,NSC 325316
	Deacylcortivazol (DAC) is a potent glucocorticoid. When incubated with glucocorticoid-resistant mutants derived from the glucocorticoid-sensitive human leukemic cell line CEM-C7, DAC caused significant growth inhibition....
T11313	Forodesine hydrochloride	BCX-1777 hydrochloride,Immucillin-H hydrochloride	Others
	Forodesine hydrochloride (BCX-1777 hydrochloride), a potent inhibitor of human lymphocyte proliferation, effectively induces apoptosis in leukemic cells by elevating dGTP levels. This compound is an orally active, highly...		Others
T39482	Casein Kinase inhibitor A86	Casein Kinase inhibitor A86
	Casein Kinase inhibitor A86 is a highly effective and orally bioavailable inhibitor of casein kinase 1α (CK1α). Additionally, it displays inhibitory actions towards CDK7 (TFIIH) and CDK9 (P-TEFb). Furthermore, Casein Kin...
T41062	HXR9
	HXR9 is a cell-permeable peptide that acts as a competitive antagonist of the HOX/PBX interaction. It effectively inhibits the binding between HOX proteins and the transcription factor PBX, specifically in paralogue grou...
T12240	Nor-NOHA acetate	Nω-Hydroxy-nor-L-arginine acetate	Apoptosis , Arginase
	nor-NOHA acetate (Nω-Hydroxy-nor-L-arginine acetate) is a reversible inhibitor of arginase, with anti-leukemic activity, effective in endothelial dysfunction, immunosuppression, and metabolism.		Apoptosis , Arginase
T38428	Alisertib sodium	MLN 8237 sodium
	Alisertib sodium (MLN 8237) is a potent and specific inhibitor (IC50 = 1.2 nM) of Aurora A kinase, an enzyme involved in cell division. By binding to Aurora A kinase, Alisertib sodium disrupts the formation of the mitoti...
T78733	ZLD115
	ZLD115 (compound 44), a derivative of FB23, functions as an inhibitor of the Fat Mass and Obesity-associated Protein (FTO) and demonstrates antiproliferative properties as an antileukemic agent against leukemic cell line...
T67930	CWI1-2		Apoptosis
	CWI1-2 is a potent IGF2BP2 inhibitor that inhibits its interaction with M6A-modified target transcripts by binding IGF2BP2. CWI1-2 has anti-leukemic activity and can induce apoptosis and differentiation.		Apoptosis
T61101	FLT3-IN-13
	FLT3-IN-13 (compound 20) is a highly effective inhibitor targeting both topoisomerase II and FLT3 proteins in leukemic cells. It exhibits potent activity against these targets, with IC50 values of 2.26 μM for both. Moreo...
T39584	MI-3454
	MI-3454 is a highly potent, orally active, and selective inhibitor of the interaction between menin and MLL1, with an IC50 of 0.51 nM. This compound effectively inhibits the proliferation of leukemic cells and promotes t...
T35429	AC-4-130
	AC-4-130, a powerful inhibitor of the SH2 domain of STAT5, effectively hinders STAT5 activation, dimerization, nuclear translocation, and transcription of genes reliant on STAT5. This compound directly binds to STAT5, ul...
T36978	AS-99 TFA
	AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 TFA blocks cell proliferation, induces apoptosis and different...
T36977	AS-99 free base
	AS-99 is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, ...
T63332	BCR-ABL-IN-5
	BCR-ABL-IN-5 is a Bcr-Abl (Breakpoint cluster region-Abelson) kinase inhibitor that acts on Bcr-AblWT (IC50: 0.014 μM) and Bcr-AblT3151 (IC50: 0.45 μM) and exhibits some anti-proliferative effects on leukemic cells. effe...
T76185	N-Myristoyl-Lys-Arg-Thr-Leu-Arg
	N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor, demonstrating an IC50 value of 75 μM. It effectively inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat [1].
T73529	AS-99
	AS-99 is a first-in-class, potent, and selective inhibitor of the ASH1L histone methyltransferase, exhibiting anti-leukemic activity with an IC50 value of 0.79 µM and a Kd of 0.89 µM. It inhibits cell proliferation, indu...
T61098	RUNX1/ETO tetramerization-IN-1
	RUNX1/ETO tetramerization-IN-1 is a small-molecule inhibitor that specifically targets NHR2 of RUNX1/ETO, effectively inhibiting the tetramerization process. With an EC50 value of 0.25 μM, this compound successfully rest...
T80737	ZG36
	ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrial dysfunction and inducing leukemic cell death. Additionally, ...
T76893	Lusvertikimab
	Lusvertikimab (OSE-127), a humanized IL7R monoclonal antibody, does not get internalized by target cells and inhibits IL7R heterodimerization along with subsequent downstream signaling. It demonstrates anti-leukemic prop...
T79133	UC-764864		E1/E2/E3 Enzyme
	UC-764864, a UBE2N inhibitor, impedes the enzymatic activity of UBE2N and exhibits cytotoxic effects through the disruption of UBE2N-dependent signaling in leukemic cells. It effectively hinders the ubiquitination of sub...		E1/E2/E3 Enzyme
T71400	Quizartinib HCl
	Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III recept...
T82259	Grisnilimab setaritox	WT1-RTA
	Grisnilimab setaritox (WT1-RTA), an anti-CD7 antihuman T cell antibody linked to ricin A chain (RTA), exhibits in vitro cytotoxicity against CEM (T-lymphoblastic leukemia) cells with an ID 50 of 53 pM. The 30-kDa RTA com...
T78871	PLM-101
	PLM-101 is an anticancer compound orally active against acute myeloid leukemia by targeting FLT3 and RET. It impedes RET function, promoting autophagic breakdown of FLT3, and suppresses the PI3K and Ras/ERK pathways, con...
T76213	HXR9 hydrochloride
	HXR9 hydrochloride, a cell-permeable peptide and competitive antagonist of the HOX/PBX interaction, selectively reduces cell proliferation and induces apoptosis in cells with elevated HOXA/PBX3 gene expression, notably M...
T83930	SJ 11646
	SJ 11646, a potent lymphocyte-specific protein tyrosine kinase (LCK) Degrader (PROTAC) with a DC50 of 0.00838 pM, utilizes Dasatinib as the LCK ligand and incorporates a phenyl glutarimide-based cereblon binder. Demonstr...

Compounds

ICCB280

T8839

Synonym:

Target: Apoptosis, Others

Rilmenidine Phosphate

T6641

Synonym:

Target: Apoptosis, Adrenergic Receptor, Autophagy, Imidazoline Receptor

Piribedil

T3278

Synonym: EU-4200,Trivastan,ET-495,Trivastal

Target: Dopamine Receptor, Histone Methyltransferase, Adrenergic Receptor

Unesbulin

T12575

Synonym: PTC596

Target: Apoptosis, BMI-1

m-3M3FBS

T8531

Synonym:

Target: Apoptosis, Phospholipase

TCS-PIM-1-4a

T4215

Synonym: SMI-4a

Target: Apoptosis, Pim

Eltanexor

T11766L

Synonym: ONO-7706,KPT-8602,ATG-016

Target: Epigenetic Reader Domain

Forodesine

T15337

Synonym: BCX-1777,Immucillin-H

Target: Others

AKI603

T64338

Synonym: AKI 603,AKI-603

Target: Aurora Kinase

Cytarabine triphosphate

T38718

Synonym: Cytarabine triphosphate,Ara-CTP

3',3'-cGAMP sodium salt

Synonym: UNII-3JO09QT49F,DAC,NSC 325316

Target:

Forodesine hydrochloride

T11313

Synonym: BCX-1777 hydrochloride,Immucillin-H hydrochloride

Target: Others

Casein Kinase inhibitor A86

T39482

Synonym: Casein Kinase inhibitor A86

Synonym: Nω-Hydroxy-nor-L-arginine acetate

Target: Apoptosis, Arginase

Alisertib sodium

T38428

Synonym: MLN 8237 sodium

N-Myristoyl-Lys-Arg-Thr-Leu-Arg

RUNX1/ETO tetramerization-IN-1

Target: E1/E2/E3 Enzyme

Grisnilimab setaritox

Cat No.	Product Name	Synonyms	Targets
T2S1040	Jolkinolide B		ERK , IL Receptor , BCL , p38 MAPK , TNF , NF-κB , Akt , Caspase , PI3K , JAK , JNK , STAT , mTOR
	Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud. Jolkinolide B induces apoptosis in cancer cells. Jolkinolide B can be used for studies on preventing and treating osteolysis.
TN5888	Toddaculin		Others
	Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-κB, ERK 1/2, and p38 MAPK signaling pathways, but can in...		Others
TN2190	Scoulerine		Apoptosis , Beta-Secretase , BACE , Parasite
	Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.		Apoptosis , Beta-Secretase , BACE , Parasite
T7730	Aminopterin	APGA,4-Aminofolic acid	Antifolate
	Aminopterin (4-Aminofolic acid) is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase		Antifolate
TN2496	1,4-Anthraquinone		Others
	1,4-Anthraquinone is an anticancer drug that blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of L1210 leukemic cells in the same nanomolar ...		Others
T6S1315	Oroxylin A	6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
	1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...		Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
T2S2215	Crebanine		Apoptosis , Others , Akt
	1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rat...		Apoptosis , Others , Akt
T83561	(2S)-4'-Hydroxy-7-methoxyflavan
	(2S)-4'-Hydroxy-7-methoxyflavan, a flavan, demonstrated significant cytotoxic effects on human leukemic Molt 4 cells [1].
TN4799	Piptocarphin F		Others
	Piptocarphin F shows strong cytotoxic activities against mouse lymphoid tumor cell line P388. It also shows cytotoxic activity (IC50 3.87-12.5 umol/L) against the human leukemic cell line HL-60.		Others

Natural Products

Jolkinolide B

T2S1040

Synonym:

Target: ERK, IL Receptor, BCL, p38 MAPK, TNF, NF-κB, Akt, Caspase, PI3K, JAK, JNK, STAT, mTOR

Target: Apoptosis, Beta-Secretase, BACE, Parasite

Aminopterin

T7730

Synonym: APGA,4-Aminofolic acid

Synonym: 6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Crebanine

T2S2215

Synonym:

Target: Apoptosis, Others, Akt

(2S)-4'-Hydroxy-7-methoxyflavan

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01410	IL-3R alpha/CD123 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-01384	Endoglin/CD105 Protein, Human, Recombinant (His)	Human	HEK293
	Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPK-01002	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-01004	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, hFc)	Human	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-01006	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, His)	Human	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-00995	CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (aa 65-267, His)	Mouse	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-01005	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His), FITC-Labeled	Human	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-00548	CLEC12A/MICL/CLL-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-01003	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His, Avi), Biotinylated	Human	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-00242	IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, His & Avi), Biotinylated	Human	HEK293
	Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 sub...
TMPY-05418	IL-3R alpha/CD123 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-04034	IL-3R alpha/CD123 Protein, Canine, Recombinant (His)	Canine	HEK293
	Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-06793	IL-3R alpha/CD123 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-00076	IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-06715	IL-3R alpha/CD123 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-06744	IL-3R alpha/CD123 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-00592	IL-3R alpha/CD123 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPK-00592	Latexin Protein, Human, Recombinant (His)	Human	E. coli
	Latexin, the endogenous protein inhibitor of the A/B subfamily of metallocarboxypeptidases, is expressed in small nociceptive neurons in sensory ganglia and in a subset of neurons in the telencephalon. Recently, the late...
TMPJ-00709	LY6H Protein, Human, Recombinant (His)	Human	Human Cells
	Lymphocyte Antigen 6H (LY6H) is a novel member of the LY6 family of glycosylphosphatidylinositol-anchored cell surface glycoproteins. LY6H contains one UPAR/Ly6 domain. Human LY6H is synthesized as a 140 amino acid precu...
TMPJ-01096	SLP-76 Protein, Human, Recombinant (His)	Human	E. coli
	Lymphocyte cytosolic protein 2（LCP2）contains a SAM domain and a SH2 domain. It is highly expressed in spleen, thymus and peripheral blood leukocytes, T-cell and monocytic cell lines, but expressed at lower level in B-cel...
TMPY-03549	Siglec-5 Protein, Human, Recombinant	Human	HEK293
	SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIG...
TMPY-02884	Siglec-5 Protein, Human, Recombinant (hFc)	Human	HEK293
	SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIG...
TMPY-04458	TRIB2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Tribbles homolog 2, also known as TRB-2, and Trib2, is a member of the protein kinase superfamily and Tribbles subfamily (Trib1, Trib2, Trib3). The identification of tribbles as regulators of signal processing systems an...
TMPY-00783	Endoglin/CD105 Protein, Human, Recombinant (hFc)	Human	HEK293
	Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPJ-00669	Siglec-5 Protein, Human, Recombinant (His & Flag & hFc)	Human	Human Cells
	Human Siglec-5 are Itype(Igtype) lectins belonging to the Ig superfamily,They are characterized by an N terminal Ig-like V type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2 type do...
TMPY-01615	Endoglin/CD105 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPY-02627	Oncostatin M/OSM Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that has functions mainly in cell growth. Oncostatin M (OSM) is considered as a pleiotropic cytokine that signals through cell surfa...
TMPY-00283	Oncostatin M/OSM Protein, Human, Recombinant	Human	HEK293
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that has functions mainly in cell growth. Oncostatin M (OSM) is considered as a pleiotropic cytokine that signals through cell surfa...
TMPY-02364	Oncostatin M/OSM Protein, Human, Recombinant (His)	Human	HEK293
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that has functions mainly in cell growth. Oncostatin M (OSM) is considered as a pleiotropic cytokine that signals through cell surfa...
TMPY-04062	Oncostatin M/OSM Protein, Mouse, Recombinant	Mouse	E. coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that has functions mainly in cell growth. Oncostatin M (OSM) is considered as a pleiotropic cytokine that signals through cell surfa...