epithelium — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15133	Dinoprost	Prostaglandin F2a,PGF2α	Endogenous Metabolite
	Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.		Endogenous Metabolite
T4546	Dinoprost tromethamine salt	Dinoprost Tromethamine,Zinoprost,Prostin F2 alpha,PGF2α THAM,Dinolytic,Prostaglandin F2α THAM	Apoptosis , Endogenous Metabolite , Prostaglandin Receptor , Autophagy , PROTAC Linker
	Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
T4977	Sofalcone	SU-88	Antibacterial , Autophagy
	Sofalcone (SU-88), a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.		Antibacterial , Autophagy
T4182	Lavendustin B		Tyrosinase , transporter , HIV Protease
	Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75).		Tyrosinase , transporter , HIV Protease
T10938	D-Kynurenine	(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103	GPR , AhR , Endogenous Metabolite
	D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluor...		GPR , AhR , Endogenous Metabolite
T3S0509	Gaultherin		COX
	Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, w...		COX
T25466	GS-9191	GS 9191	DNA/RNA Synthesis
	GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetrates the skin and is metabolized in the epithelium to an ac...		DNA/RNA Synthesis
T34710	STA 2	ONO 11113,STA-2,STA2
	STA 2 is an analogue of TXA2, a thromboxane receptor in the colonic epithelium.
T34551	SC 32855	SC-32855,SC32855
	SC 32855 is a 1,4-benzodiazepine that has been shown to arrest of spermatogenesis and degeneration of the germinal epithelium.
T34566	Sch 12223	Sch12223,Sch-12223
	SCH 12223 is a unique drug that protects the stomach and intestinal epithelium from harmful irritation.
TP2253	GLP-2(rat)	GLP-2 (rat)	Others
	intestinal epithelium-specific growth factor		Others
TP1157	GLP-2(1-33)(human)	GLP-2 (human),Glucagon-like peptide 2 (human)
	GLP-2(1-33) (human) is an enteroendocrine hormone which stimulates the growth of the intestinal epithelium.
T68682	Piriprost
	Piriprost is a leukotriene inhibitor attenuates the smoke-induced increase in alveolar-capillary barrier permeability and decrease in plasminogen activator activity and causes a swelling of type I alveolar epithelium.
T81341	Pyr-Gly
	Pyr-Gly is an inhibitory peptide that suppresses the proliferation of retinal pigment epithelium (RPE) cells and fibroblasts [1].
T11124	Duramycin	Lancovutide,Moli1901	Others
	Duramycin is a cyclic peptide lantibiotic derived from Streptomyces cinnamoneuma. Duramycin interacts with phosphatidylethanolamine (PE) and has antibacterial, antiviral effects. Duramycin stimulates chloride secretion ...		Others
T76806	Bezlotoxumab
	Bezlotoxumab, a human monoclonal antibody, targets and binds to Clostridium difficile (C. difficile) toxin B, thereby inhibiting its ability to damage intestinal epithelium and cause colitis [1].
TP1487	Glucagon-Like Peptide (GLP) II, human
	Glucagon-like peptide 2 (GLP-2) is a recently identified intestinal epithelium-specific growth factor that has been shown to reduce the severity of inflammatory disorders of the intestine in rodent models. Currently Gluc...
T69429	Y27632 HCl hydrate
	Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriuretic peptide production, cell size, protein synthesis, and myofibrillar organization. Y27632 prevents dimethylnitrosamine-induced hepa...
T81720	N,N'-Dinitrosopiperazine	1,4-Dinitrosopiperazine,DNP
	N,N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine; DNP) is a carcinogen targeting nasopharyngeal epithelium that promotes nasopharyngeal carcinoma (NPC) metastasis. It modulates various signaling pathways via protein pho...
T74699	Avacincaptad pegol
	Avacincaptad pegol, a pegylated aptamer, stands out as an effective C5 complement inhibitor capable of mitigating inflammation-induced damage to the retinal pigment epithelium (RPE). This compound is under investigation ...