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Cat No. | Product Name | Synonyms | Targets |
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T22774L | Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) | Others | |
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub... | |||
T22774 | Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species] | Others | |
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. ... | |||
T60491 | Elongation factor P-IN-1 | ||
Elongation factor P-IN-1 is a potent elongation factor P (EFP) inhibitor that is a β-lysine derivative compound. Elongation factor P-IN-1 affects E. coli proliferation rate[1]. | |||
T60682 | Elongation factor P-IN-2 | ||
Elongation factor P-IN-2 is a β-lysine derivative compound which is a potent elongation factor P (EFP) inhibitor. Elongation factor P-IN-2 affects the E. coli proliferation rates [1]. | |||
TQ0137 | A-484954 | A 484954 | CaMK , Parasite , Autophagy |
A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor. | |||
T21152 | Ac-Phe-NH2 | Ac-Phe NH2,Ac Phe NH2,Ac Phe-NH2 | Others |
Ac-Phe-NH2 is a non-competitive inhibitor of polyubiquitin chain elongation at Ki value of 8 ± 1.2 mM. | |||
T72076 | H2-Gamendazole | HSP | |
H2-Gamendazole is a novel compound for spermatogenesis inhibition and cancer therapy as an inhibitor of heat shock proteins and/or elongation factor 1 alpha, and is an Hsp90 regulator. | |||
T8886 | NITD-2 | DNA/RNA Synthesis | |
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in hu... | |||
T13974 | ZL0580 | Epigenetic Reader Domain , HIV Protease | |
ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter. | |||
T16710 | Mericitabine | R-7128,RG 7128,PSI 6130 diisobutyrate | HCV Protease |
Mericitabine (R-7128) is a nucleoside HCV NS5B polymerase inhibitor. It acts as an RNA chain terminator and prevents the elongation of RNA transcripts during replication. | |||
T60619 | CDK9-IN-15 | CDK | |
CDK9-IN-15 is a potent small molecule CDK9 inhibitor, which can block the phosphorylation of positive transcription elongation factor b (P-TEFb) on the C-terminal region of RNA Poly-II by degradation and inhibition of CD... | |||
T23840 | BUR1 | BMP upregulator-1,BMP upregulator 1,BUR 1,BUR-1 | CDK |
BUR1 is a selective BMP upregulator that acts by increasing the expression of Inhibitor of DNA binding 1 and inducing BMP2 and PTGS2 expression. | |||
T60219 | ELOVL1-IN-3 | Others | |
ELOVL1-IN-3 is a potent and orally active inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme. ELOVL1-IN-3 serves as a useful tool for researching adrenoleukodystrophy (ALD). | |||
T16868 | SEC inhibitor KL-2 | KL-2 | Others |
SEC inhibitor KL-2 (KL-2) (KL-2) is a potent, selective super elongation complex (SEC) inhibitor. SEC inhibitor KL-2 exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 1.50 μM). | |||
T12006 | Metarrestin | ML246 | DNA/RNA Synthesis |
Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (... | |||
T16867 | SEC inhibitor KL-1 | KL-1 | Others |
SEC inhibitor KL-1 (KL-1) exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 3.48 μM). SEC inhibitor KL-1 is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interacti... | |||
T60627 | ELOVL1-IN-2 | Others | |
ELOVL1-IN-2, a compound known as an inhibitor of the elongation of very long chain fatty acid 1 (ELOVL1) enzyme, exhibits a weak inhibitory effect on ELOVL1 (with an IC50 of 21 μM) and demonstrates moderate potency in a ... | |||
T27822 | LFF 571 | LFF571,LFF-571 | |
LFF 571 is an inhibitor of protein-synthesizing GTPase (Elongation Factor). | |||
T29260 | (R)-ß-lysine | R ß lysine,MG1655,R-ß-lysine,(R) ß lysine,MG-1655 | |
(R) - ß - lysine is a functional modifier of elongation factor P (EF-P). | |||
T10436L | AZD4573 HCl (2057509-72-3 free base) | AZD4573 hydrochloride,AZD4573,AZD4573 HCl,AZD-4573,AZD 4573 | |
AZD-4573 is a selective and short-acting inhibitor of the serine/threonine cyclin-dependent kinase 9, the catalytic subunit of the RNA polymerase II elongation factor positive transcription elongation factor b. It also h... | |||
T71263 | CBL0100 | ||
CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation. | |||
T26001 | Pulvomycin | Antibiotic 1063Z | |
Pulvomycin is a protein biosynthesis inhibitor preventing ternary complex formation between elongation factor Tu, GTP, and aminoacyl-tRNA. | |||
T35356 | Gibberellins A4/A7 | Gibberellin A4&A7,Gibberellins A4/A7 | Others |
Gibberellins A4/A7 (Gibberellin A4 and A7) is the Gibberellin A4 Mixture With Gibberellin A7. Gibberellins A4/A7 promotes internode elongation & breaks certain dormancies in seeds. Gibberellins A4/A7 is an endogenous pla... | |||
T24272 | KT5926 | KT 5926,KT-5926 | |
KT5926 is an effective and selective inhibitor of myosin light chain kinase. KT5926 is an analogue of K-252a, which blocks all responses to NGF. KT5926 selectively inhibits nerve growth factor-dependent neurite elongatio... | |||
T71815 | TX-1918 | ||
TX-1918 is a cell-permeable tyrphostin derivative that inhibits eukaryotic elongation factor-2 kinase (eEF-2K). TX-1918 disrupts the proliferation of HepG2 and HCT116 tumor cells. | |||
T70918 | GE-2270 A | ||
GE-2270 A inhibits bacterial protein synthesis in vitro via the GTP-bound form of elongation factor Tu. | |||
T26973 | Cefatrizine | Cephatriazine,BL-S-640,BLS640,S 640P,BL S 640 | |
Cefatrizine is an inhibitor of eukaryotic elongation factor-2 kinase, a unique calcium/calmodulin-dependent protein kinase, is well known to regulate apoptosis, autophagy and ER stress in many types of human cancers. | |||
T40880 | (±)-Jasmonic acid | ||
(±)-Jasmonic acid, a plant growth regulator and derivative of α-linolenic acid, exhibits chlorophyll-lowering effects in green and etiolated barley leaf segments, while also inhibiting the elongation of rice seedlings. | |||
T24330 | L 681217 | L-681,217,L-681217,L681,217,L 681,217,L681217 | |
L 681217 is a glycolipid-type antibiotic related to the efrotomycin class. L-681217 inhibits bacterial protein synthesis at the elongation stage. L 681217 shows broad-spectrum antibiotic activity against Gram-positive an... | |||
T74115 | Decanoyl coenzyme A | ||
Decanoyl coenzyme A (Decanoyl CoA) serves as a primer for the fatty acid elongation system in Mycobacterium smegmatis [1]. | |||
T36600 | Cefsulodin (sodium salt hydrate) | ||
Cefsulodin is a β-lactam antibiotic that lyses actively-growingE. coliby binding specifically to the intermembrane proteins, penicillin-binding proteins 1a and b, whose transglycosylase and transpeptidase activities are ... | |||
T27128 | DCB-3503 | NSC716802,NSC 716802,NSC-716802,DCB3503,DCB 3503 | |
Tylophorine analog DCB-3503 is a potential anticancer and immunosuppressive agent. DCB-3503 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. DCB-3503 allosterically... | |||
T28266 | Org-6906 | Org6906,Org 6906,Org-6906 free | |
Tylophorine analog DCB-3503 is a potential anticancer and immunosuppressive agent. DCB-3503 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. DCB-3503 allosterically... | |||
T78637 | DdTTP trisodium | DNA/RNA Synthesis | |
Dideoxythymidine triphosphate trisodium (ddTTP), a 2',3'-dideoxyribonucleoside 5'-triphosphate (ddNTP), functions as a chain-elongation inhibitor of DNA polymerase in DNA sequencing applications [1]. | |||
T74108 | DdTTP | ||
ddTTP, a 2',3'-dideoxyribonucleoside 5'-triphosphate (ddNTP), serves as a chain-elongation inhibitor of DNA polymerase in DNA sequencing [1]. | |||
T38353 | Pyrenocine A | ||
Pyrenocine A is a fungal metabolite that has been found inP. terrestrisand has diverse biological activities.1It inhibits the asexual spore germination of the plant pathogenic fungiF. oxysporum,F. solani,M. hiemalis, and... | |||
T11534L | Haemanthamine hydrochloride (466-75-1 free base) | Haemanthamine hydrochloride | Others |
Haemanthamine hydrochloride is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-ap... | |||
TP2247 | Eukaryotic translation initiation factor 3 | Others | |
Eukaryotic initiation factors (eIF) are proteins involved in the initiation phase of eukaryotic translation. Eukaryotic translation initiation factor 3 binds to the ribosome subunit-mRNA complex. It has been implicated i... | |||
T36214 | 16,16-dimethyl Prostaglandin E1 | 16,16-dimethyl Prostaglandin E1 | |
16,16-dimethyl Prostaglandin E1 is a PGE1 (T1626) analog that induces bronchoconstriction and vascular smooth muscle contraction and inhibits indomethacin-induced cell elongation. | |||
T75419 | Alpha-2,8-Sialyltransferase (CstII) | ||
Alpha-2,8-Sialyltransferase (CstII) (ST8Sia VI), belonging to the alpha2,8-sialyltransferase (ST8Sia) family, primarily catalyzes the elongation of the α2,8-linked oligo/polysialic acid chain on the sialic acid (Sia) res... | |||
T83836 | 3'-O-Methylguanosine-5'-O-triphosphate sodium | 3'-O-methyl GTP | |
3'-O-Methylguanosine-5'-O-triphosphate (3'-O-methyl GTP), a methylated derivative of GTP, serves as a chain termination reagent in synthesizing early RNA polymerase II elongation intermediates. | |||
T37677 | 3-hydroxy Docosanoic Acid | ||
3-hydroxy Docosanoic acid is a hydroxylated form of the 22-carbon saturated docosanoic acid . It is found in lipopolysaccharides from C. trachomatis and C. psittaci and in S. synnaedendra. 3-hydroxy Docosanoic acid, in t... | |||
T37678 | 3-hydroxy Lignoceric Acid | ||
3-hydroxy Lignoceric acid is a hydroxylated form of the 24-carbon saturated lignoceric acid . 3-hydroxy Lignoceric acid is found in minor amounts in Methyloligella, a novel Gram-negative bacteria. 3-hydroxy Lignoceric ac... | |||
T62417 | MELK-8a | ||
MELK-8a (NVS-MELK8a) is a potent and selective inhibitor of maternal embryonic leucine elongation kinase (MELK) (IC50: 2 nM). 0.42 μM). Among them, MELK plays an important role in regulating mitosis in cancer cells. | |||
T60965 | Anticandidal agent-1 | ||
Anticandidal agent-1 (compound c2) is a potent and broad-spectrum anticandidal agent that inhibits biofilm through blocking hyphal elongation and filamentation. Anticandidal agent-1 exhibits anticandidal activity against... | |||
T60709 | Acyclovir monophosphate | ||
Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agen which also has antitumor activity. Acyclovir monophosphate blocks synthesis of DNA by inhibiting the viral DNA polymerase and terminates the chain ... | |||
T36045 | 1a,1b-dihomo Prostaglandin E2 | 1a,1b-dihomo Prostaglandin E2 | |
1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid . 1a,1b-dihomo PGE2 has also b... | |||
T12135 | Mycophenolic acid-d3 | Mycophenolate-d3,Mycophenolate D3 | Others , Antibacterial |
Mycophenolic acid-d3 (Mycophenolate-d3) is a derivative of Mycophenolic acid. Mycophenolic acid is a compound that reduces GTP level and impacts transcription elongation of RNA polymerase II (RNAP II), promotes proximal ... | |||
T79579 | DdUTP | 2′,3′-Dideoxyuridine-5′-triphosphate | Reverse Transcriptase |
ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) serves as a selective inhibitor of HIV and AMV reverse transcriptases with Ki values of 0.05 µM for HIV and 1 µM for AMV, respectively. This compound is preferentially incorpo... | |||
T38151 | Germicidin A | ||
Germicidin A is a pyranone originally derived from S. viridochromogenes that acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as... |
Cat No. | Product Name | Synonyms | Targets |
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T1160 | Fusidic acid | Fusidine | Others , CAT , Antibacterial , Antibiotic |
Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum. | |||
T1289 | Fusidic acid sodium salt | Sodium fusidate,Fusidate Sodium,Fucidin,SQ-16360 | Others , CAT , Antibacterial , Antibiotic |
Fusidic acid sodium salt (SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections. | |||
T3151 | Brassinolide | Brassin lactone,24-Epibrassinolide | Apoptosis , Others |
Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division. | |||
T7132 | (Rac)-Brassinazole | BRASSINAZOLE | P450 |
(Rac)-Brassinazole are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a triazole-type brassinosteroid biosynth... | |||
T6512 | G-418 disulfate | Geneticin,G418 Sulfate,Antibiotic G-418 sulfate,Geneticin sulfate | Antibacterial , Antibiotic |
G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, an inhibitor of protein synthesis with eukaryotic selectivity. G-418 disulfate blocks peptide synthesis by inhibiting peptide chain elongation. | |||
T9715 | Aplidine | SARS-CoV , DNA/RNA Synthesis | |
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM). | |||
T21430 | Oxytetracycline Hydrochloride | Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin | Antiviral , Endogenous Metabolite , Antibacterial , HSV |
Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resultin... | |||
T3380 | Homoharringtonine | Myelostat,Ceflatonin,HHT,Omacetaxine mepesuccinate | STAT |
Homoharringtonine (HHT) is a natural alkaloid that inhibits the translation of proteins and is cytotoxic. Homoharringtonine acts on the ribosomes of tumor cells to inhibit the elongation step of protein translation, ther... | |||
T20945 | 2,4-D | Hedonal,Macondray,2,4-D acid,Chloroxone | DNA/RNA Synthesis |
2,4-Dichlorophenoxyacetic acid (Hedonal) is a synthetic auxin used as a plant growth regulator and also used as a supplement in plant cell culture media. It is an active ingredient in herbicides used to disrupts the acti... | |||
T5088 | 3-Indoleacetic acid sodium | Indole-3-Acetic Acid sodium salt,Sodium 2-(1H-indol-3-yl)acetate,IAA sodium salt,Heteroauxin sodium salt | Others , Endogenous Metabolite |
3-Indoleacetic acid sodium (Heteroauxin sodium salt) is a naturally occurring plant hormone of the auxin class. It can stimulate cell elongation and division, promoting plant growth and development. However, at high conc... | |||
TN3861 | Dihydropinosylvin | Anti-infection | |
Dihydropinosylvinin is an phytoalexin, it shows antifungal activity against Cladosporium cladosporioides, Botryodiplodia theobromae, Aspergillus niger and Penicillium schlerotgenum, it also exhibits strong antibacterial ... | |||
TMM2618 | Gibberllin A7 | Gibberellin A7,Gibberllin 7 | Others |
Gibberllin A7 (Gibberllin 7) is important plant growth hormones that promote plant cell growth and elongation. Gebberillins promote rapid stem and root growth, induce mitotic division and initiate (break dormancy) and in... | |||
TN4509 | Medicarpin 3-O-glucoside | Others | |
Medicarpin-3-O-glucoside, a phytoalexin, inhibits the germination of G. intraradices spores and hyphal elongation. | |||
T11534 | Haemanthamine | Others | |
Haemanthamine is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiv... | |||
TN4570 | Minumicrolin | Others | |
Minumicrolin is a plant growth inhibitor against the 2nd leaf sheath elongation of rice seedlings. Murrangatin exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100, it might be valuable anti-tumor-promotin... | |||
T38275 | Kirromycin | ||
Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis. It inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of B. brevis. Kirromycin inhibits ... | |||
T15703 | Lactimidomycin | Others | |
Lactimidomycin, isolated from Streptomyces, is an inhibitor of eukaryotic translation elongation. It is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Lactimidomycin has an antiproliferati... | |||
T82629 | Cytochalasin K | ||
Cytochalasin K (Compound 7) is a cytochalasin known to inhibit wheat root elongation, exhibiting an IC50 value of 22.58 μM [1]. | |||
TN4623 | Nagilactone C | Antifection | |
Nagilactone C and phyllanthoside are novel protein synthesis inhibitors, they are specific for the eukaryotic translation apparatus, function in vivo and in vitro, and interfere with translation elongation. Nagilactone C... | |||
T83466 | 10-Phenyl-[12]-cytochalasins Z16 | ||
10-Phenyl-[12]-cytochalasins Z16 (Compound 5), a member of the cytochalasins, exhibits inhibition of wheat root elongation with an IC50 of 17.35 μM [1]. | |||
T80346 | Tur1A | ||
Tur1A, an antimicrobial peptide sourced from the bottlenose dolphin (Tursiops truncates), impedes bacterial protein synthesis. It achieves this inhibition by attaching to ribosomes and obstructing the progression from th... | |||
T15039 | Cytochalasin E | Others | |
Cytochalasin E is a potent actin depolymerization agent and an epoxide containing Aspergillus-derived fungal metabolite. Cytochalasin E also inhibits angiogenesis and tumor growth. It binds and caps the barbed end of act... | |||
T73813 | Haemanthamine hydrochloride | ||
Haemanthamine hydrochloride, a crinine-type alkaloid derived from Amaryllidaceae plants, exhibits potent anticancer properties. It acts by targeting ribosomes, thereby inhibiting protein biosynthesis during the translati... | |||
T36992 | Monocerin | ||
Monocerin is a fungal metabolite that has been found inF. larvarumand has diverse biological activities.1,2,3It is active against the bacteriaE. coliandB. megaterium, the phytopathogenic fungusM. violaceum, and the algaC... | |||
T83693 | Magainin 2 TFA | MG2 | |
Magainin 2, a cationic peptide derived from the African clawed frog (X. laevis) skin, exhibits host defense and antimicrobial properties. This compound effectively inhibits a range of pathogens, including E. coli, K. pne... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00020 | Elongation factor Tu Protein, Acinetobacter baumannii, Recombinant (His) | Acinetobacter baumannii | Yeast |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. | |||
TMPY-03608 | EEF1B2 Protein, Human, Recombinant (His) | Human | E. coli |
EF1B, also known as EEF1B2, is a translation elongation factor. It belongs to the EF-1-beta/EF-1-delta family. Elongation factors are a set of proteins that are used in protein synthesis in the cell. In the ribosome, the... | |||
TMPH-01286 | EEF2 Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly form... | |||
TMPY-03976 | EEF1E1 Protein, Human, Recombinant (His) | Human | E. coli |
EEF1E1, also known as AIMP3 and p18, is a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, EEF1E1 is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex... | |||
TMPH-03742 | EEF1A1 Protein, Cricetulus griseus, Recombinant (His) | Chinese hamster | E. coli |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF... | |||
TMPH-01285 | EEF1D Protein, Human, Recombinant (His) | Human | E. coli |
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.; Regulates induction of heat-shock-responsive g... | |||
TMPH-01284 | EEF1A1 Protein, Human, Recombinant | Human | E. coli |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF... | |||
TMPH-01283 | EEF1A1 Protein, Human, Recombinant (His) | Human | E. coli |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF... | |||
TMPH-00565 | FabB Protein, E. coli, Recombinant (His & Myc & SUMO) | E. coli | E. coli |
Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can also use unsaturated fatty acids. Catalyz... | |||
TMPH-01753 | Netrin-4/NTN4 Protein, Human, Recombinant (GST & His & Myc) | Human | E. coli |
May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants. | |||
TMPH-03536 | FabI Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism. | |||
TMPH-00564 | FabG Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. | |||
TMPH-00089 | SPT16 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) | Arabidopsis thaliana | E. coli |
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication an... | |||
TMPH-02385 | Lake Victoria marburgvirus (MARV) (strain Musoke-80) VP30 Protein (His & Myc) | MARV | E. coli |
Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation. This function has been found to be dependent on the formation of an RNA secondary ... | |||
TMPH-03168 | Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) | Pseudomonas aeruginosa | E. coli |
An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65... | |||
TMPH-03404 | Reovirus type 3 (strain Dearing) Outer capsid protein sigma-3 (His) | Reo-3 | E. coli |
Stimulates translation by blocking the activation of the dsRNA-dependent protein kinase EIF2AK2/PKR, thereby inhibiting the host interferon response. Sigma3 prevents the activation of EIF2AK2 by competing with the kinase... | |||
TMPH-02111 | SRP72 Protein, Human, Recombinant (GST) | Human | E. coli |
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might intera... | |||
TMPH-02654 | FGF-5 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression fro... | |||
TMPH-01335 | FGF-5 Protein, Human, Recombinant (GST & His & Myc) | Human | E. coli |
Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression fro... | |||
TMPH-03049 | Gel4 Protein, Neosartorya fumigata, Recombinant (E. coli, His) | Neosartorya fumigata | E. coli |
Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in ... | |||
TMPH-03050 | Gel4 Protein, Neosartorya fumigata, Recombinant (His) | Neosartorya fumigata | Yeast |
Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in ... | |||
TMPY-03492 | B3GALTL Protein, Human, Recombinant (His) | Human | HEK293 |
B3GALTL is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. B3GALTL is a type II membrane protein. Defects in B3GALTL gene ar... | |||
TMPH-01649 | PMEL Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, ... | |||
TMPH-02251 | TMOD1 Protein, Human, Recombinant (GST) | Human | E. coli |
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane ... | |||
TMPH-00505 | RPB1 Protein, Drosophila melanogaster, Recombinant (His) | Fruit fly | Yeast |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors a... | |||
TMPH-02187 | Tenascin Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown o... | |||
TMPH-01288 | Elongin-B Protein, Human, Recombinant (GST) | Human | E. coli |
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its... | |||
TMPH-01800 | Nucleolin Protein, Human, Recombinant (His) | Human | Yeast |
Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is ... | |||
TMPY-03051 | B3GNT2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
B3GNT2 belongs to the beta-1,3-N-acetylglucosaminyltransferase family. It is a type II transmembrane protein that prefers the substrate of lacto-N-neotetraose. Alternative splicing produced 2 isoforms of the human protei... | |||
TMPH-00898 | Human adenovirus C serotype 5 DNA-binding protein (His) | HAdV-5 | Baculovirus |
Plays a role in the elongation phase of viral strand displacement replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers. Also enhances the rate of initiation. Relea... | |||
TMPH-00896 | Human adenovirus C serotype 2 DNA-binding protein (His) | HAdV-2 | E. coli |
Plays a role in the elongation phase of viral strand displacement replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers. Also enhances the rate of initiation. Relea... | |||
TMPH-01240 | MCM2 Protein, Human, Recombinant (His) | Human | E. coli |
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites ... | |||
TMPH-03411 | Ricin Protein, Ricinus communis, Recombinant (His) | Ricinus communis | E. coli |
Ricin is highly toxic to animal cells, and to a lesser extent to plant cells.; Acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breaka... | |||
TMPH-00532 | SSB Protein, Enterobacteria phage T7, Recombinant | Enterobacteria phage T7 | Yeast |
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advance... | |||
TMPY-03174 | CFHR1 Protein, Human, Recombinant (His) | Human | HEK293 |
CFHR1 is a secreted protein belonging to the complement factor H protein family.The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) a... | |||
TMPJ-00878 | NPR3 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Atrial Natriuretic Peptide Receptor-3 (NPR3), also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of v... | |||
TMPH-00531 | SSB Protein, Enterobacteria phage T7, Recombinant (His & SUMO) | Enterobacteria phage T7 | E. coli |
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advance... | |||
TMPY-03521 | DcR3 Protein, Human, Recombinant (hFc) | Human | Baculovirus-Insect Cells |
Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) also known as DcR3(Decoy Receptor 3) and M68 is the tumor necrosis factor receptor superfamily. DcR3/TNFRSF6B belongs to the tumor necrosis factor receptor ... | |||
TMPH-02926 | TRET Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic c... | |||
TMPJ-01317 | EXTL2 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Exostosin-like 2 (EXTL2) is a member of the exostosin (EXT)-related family which contains five members: EXT1, EXT2, EXTL1, EXTL2, and EXTL3. Studies have shown that EXT gene family members have the activities of heparan ... | |||
TMPH-02186 | TERT Protein, Human, Recombinant (His) | Human | E. coli |
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic c... | |||
TMPY-04775 | CDK1 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
CDC2, also known as CDK1, contains 1 protein kinase domain and belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily. CDC2 is a catalytic subunit of the highly conserved prote... | |||
TMPH-02959 | Tsukushi Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Contributes to various developmental events and other processes such as wound healing and cholesterol homeostasis through its interactions with multiple signaling pathways. Wnt signaling inhibitor which competes with WNT... | |||
TMPY-04549 | CDK1 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
CDC2, also known as CDK1, contains 1 protein kinase domain and belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily. CDC2 is a catalytic subunit of the highly conserved prote... | |||
TMPJ-01351 | XPNPEP1 Protein, Human, Recombinant (His) | Human | E. coli |
X-Prolyl Aminopeptidase (XPNPEP1) is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because ... | |||
TMPH-02539 | MGAT3 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannos... | |||
TMPH-00711 | BioH Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of th... | |||
TMPH-03008 | ENR Protein, Mycobacterium tuberculosis, Recombinant (His) | Mycobacterium tuberculosis | E. coli |
Enoyl-ACP reductase of the type II fatty acid syntase (FAS-II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the ... | |||
TMPH-02288 | UBE2D3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'-linked polyubiquitination. Cooperates with the E2 CDC34 and the SCF(FBXW11)... | |||
TMPH-02133 | DDX39B Protein, Human, Recombinant (GST) | Human | E. coli |
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mR... | |||
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