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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15727 | Sonidegib diphosphate | NVP-LDE 225 diphosphate,Erismodegib diphosphate,LDE225 diphosphate | Smo |
Sonidegib diphosphate (LDE225 diphosphate) is an effective and selective Smo antagonist (IC50: 1.3 nM and 2.5 nM for mouse and human Smo in a binding assay, respectively). | |||
T2691 | Oritavancin diphosphate | LY333328 diphosphate | Others , Antibacterial , Antibiotic |
Oritavancin diphosphate (LY333328 diphosphate) is a novel semisynthetic glycopeptide antibiotic which is being developed for the treatment of serious Gram-positive bacterial infections. | |||
T31163 | Cytidine 5'-diphosphate disodium | CDP sodium salt,Cytidine 5'-diphosphate disodium salt,Cytidine diphosphate sodium salt | Others |
Cytidine 5'-diphosphate disodium (CDP sodium salt) produces CTP to support DNA and RNA biosynthesis and ribonucleotide reductase to produce dCMP. | |||
T0850 | Primaquine diphosphate | Primaquine phosphate,Primaquine bisphosphate | Antibiotic , Parasite |
Primaquine diphosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the proper... | |||
T2288L | Motesanib Diphosphate | Motesanib,AMG 706 | VEGFR , c-Kit |
Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity. | |||
T7606 | Guanosine 5'-diphosphate disodium salt | 5'-GDP-Na2 | Endogenous Metabolite |
Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway. | |||
T13284 | Vapendavir diphosphate | BTA798 diphosphate | Others |
Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains). | |||
T20421 | Fluorescein diphosphate | Fluorescein diphosphate Tetraammonium salt,FDP | |
Fluorescein diphosphate is a colorless and nonfluorescent substrate for alkaline phosphatases. The sequential alkaline phosphatase mediated hydrolysis of its two phosphate substituents yielding weakly fluorescent fluores... | |||
T36880 | NHC-diphosphate | ||
NHC-diphosphate, a phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) in its diphosphate form[1], serves as a potent antiviral agent. As a pyrimidine ribonucleoside, NHC effectively counters the repl... | |||
T37909 | Tenofovir diphosphate | ||
Tenofovir diphosphate (TFV-DP) is a competitive inhibitor of DNA polymerases, specifically targeting dATP, and it serves as a substrate for the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1)[1]... | |||
T78669 | (1R,4S)-Yimitasvir diphosphate | (1R,4S)-DAG-181 diphosphate,(1R,4S)-Emitasvir diphosphate | |
Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A). It is utilized in the study of chronic hepatitis C virus infections [1]... | |||
T36881 | NHC-diphosphate triammonium | ||
NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form[1]. NHC-triphosphate triammonium is a weak alternative substrate for the viral poly... | |||
T37910 | Tenofovir diphosphate triethylamine | ||
Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive inhibitor of DNA polymerases for dATP, functioning as a substrate for HIV type 1 reverse transcriptase (HIV-1 RT)[1]. | |||
T29990 | Aminoquinol diphosphate | ||
Aminoquinol diphosphate may be useful in the treatment of acute necrotising cutaneous leishmaniasis. | |||
T68551 | Cabergoline diphosphate | ||
Cabergoline diphosphate is a dopamine D2 receptor agonist used for prolactinoma treatment. Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels. | |||
T37523 | Tenofovir diphosphate (sodium salt) | ||
Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). It is selective for these enzymes over DNA... | |||
T71518 | Zidovudine diphosphate | ||
Zidovudine diphosphate is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptas... | |||
T8735 | Sulbactum Sodium | 5'-CDP,Cytidine-5′-diphosphate | Others |
Sulbactum Sodium (5'-CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK) | |||
T83813 | 8-Azidoadenosine-5'-O-diphosphate sodium | 8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate | |
8-Azidoadenosine-5'-O-diphosphate (8-azido-ADP), a clickable variant of the ATP precursor and purinergic receptor ligand ADP, serves as a photoaffinity label for proteins including glutamate dehydrogenase (GDH) isoprotei... | |||
T11001L | Desethyl chloroquine diphosphate | Others | |
Desethyl chloroquine diphosphate is the main deethyl metabolite of chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Chloroquine diphosphate has anti-plasma activity. | |||
T26648 | Arabinose 1,5-diphosphate | ||
Arabinose 1,5-diphosphate is a bisphosphatase inhibitor. | |||
T12354L | Oxythiamine diphosphate | Others | |
Oxythiamine diphosphate is a competitivethiamine pyrophosphate inhibitor(Ki of 30 nM). | |||
T38570 | DMAPP triammonium | Dimethylallyl diphosphate triammonium,Dimethylallyl Pyrophosphate triammonium salt | Others |
DMAPP triammonium (Dimethylallyl diphosphate triammonium) is one of the prerequisite substances for an isoprenoid involved in the mevalonate (MVA) pathway, which can be used in the study of metabolism-related diseases. | |||
T37154 | 7-Methylguanosine 5'-diphosphate sodium | ||
7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, is utilized in the synthesis of mRNA cap analogues[1]. | |||
T70251 | Hexestrol diphosphate tetrasodium | ||
Hexestrol diphosphate tetrasodium is a synthetic ER agonist, microtubule polymerization inhibitor, and potential carcinogen. It induces mitotic arrest, aneuploidy, and DNA adduct formation. | |||
T19579 | Thiamine diphosphate analog 1 | Others | |
Thiamine diphosphate analog 1, an analog of Thiamine diphosphate (the active form of vitamin B1 and a universal cofactor in key cellular pathways), mirrors the structure and potentially the function of its prototype. | |||
T71927 | Adenosine-5'-diphosphate disodium salt | ||
Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue. | |||
T71609 | Hexestrol diphosphate sodium | ||
Hexestrol diphosphate sodium is a synthetic ER agonist, microtubule polymerization inhibitor, and potential carcinogen. It induces mitotic arrest, aneuploidy, and DNA adduct formation. | |||
T72120 | Guanosine 5'-diphosphate sodium | GDP sodium | |
Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate known for activating the adenosine 5'-triphosphate-sensitive K+ channel and serving as a potential iron mobilizer by inhibiting the hepcidin-ferroportin i... | |||
T83821 | Thymidine-5'-O-(α,β-methylene)diphosphate sodium | α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP | |
Thymidine-5’-O-(α,β-methylene)diphosphate (TMP-CP), a hydrolytically stable derivative of TDP, functions as an inhibitor of thymidine kinase (Ki = 23 µM). It serves as a precursor in the synthesis of α,β-methylene-2’-deo... | |||
T32764 | Linear-benzoadenosine diphosphate | Lin-benzo-ADP | |
Linear-benzoadenosine diphosphate is a nucleotide analog. | |||
T36740 | Guanosine 5’-diphosphate (sodium salt hydrate) | ||
Guanosine 5’-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5’-triphosphate .1It has been used to study the conformations of GTPases.2GDP (100 μM) activates sulfonylurea receptor 2B (SUR... | |||
T37057 | D-myo-Inositol-1,2-diphosphate (sodium salt) | ||
Ins(1,2)P2 (sodium salt) is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals. The most studied InsP Ins(1,4,5)P3, is a second me... | |||
T37060 | D-myo-Inositol-1,3-diphosphate (sodium salt) | ||
D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studie... | |||
T35572 | Adenosine 3',5'-diphosphate sodium salt | 3'-Phosphoadenosine 5'-phosphate | Endogenous Metabolite |
Adenosine 3',5'-diphosphate sodium salt is an inhibitor of hydroxysteroid sulfotransferases, which are adenine nucleotides containing a phosphate group at the 3' and 5' positions of the pentose ribose.Adenosine 3',5'-dip... | |||
T73807 | Geranyl diphosphate | ||
Geranyl diphosphate, a crucial intermediate in the isoprenoid biosynthesis pathway (IBP), significantly contributes to cellular metabolism by facilitating the production of sterol and non-sterol isoprenoids [1] [2]. | |||
T36973 | 5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate) | ||
5-Phospho-D-ribose 1-diphosphate (PRPP) is a natural intermediate involved in the pentose phosphate pathway leading to purine, pyrimidine, and histidine metabolism. It is also an intermediate in the synthesis of plant ho... | |||
T69264 | Aristeromycin diphosphate | ||
Aristeromycin diphosphate is an inhibitor of S-adenosylhomocysteine hydrolase (AHCY), inducing miR-26a and regulating oncogenic EZH2 expression, showing high inhibitory activity against AHCY, and causing growth inhibitio... | |||
T23581 | 2-Methylthioadenosine diphosphate trisodium | 2 Methylthio ADP,2MeSADP,2-Methylthio-ADP,2 MeS ADP,2-MeS-ADP | |
2-MeS-ADP is a purinergic agonist that acts by displaying selectivity for P2Y1, P2Y12, and P2Y13 receptors and inhibiting cAMP accumulation. | |||
T74588 | Yimitasvir diphosphate | ||
Yimitasvir (Emitasvir) diphosphate is an orally administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A), utilized in the research of chronic hepatitis C virus infection [1]. | |||
T78583 | Uridine 5'-diphosphate | P2Y Receptor | |
Uridine 5'-diphosphate acts as a P2Y6 receptor agonist, exhibiting an EC50 value of 0.013 μM for the human P2Y6 receptor [1]. | |||
T73980 | Thymidine 5′-diphosphate | ||
Thymidine 5′-diphosphate (dTDP), a crucial product of pyrimidine synthesis in organisms, is synthesized through the thymidylate kinase (TMPK)-catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), requiring ATP ... | |||
T64282 | Oxythiamine diphosphate ammonium | ||
Oxythiamin diphosphate ammonium is a potent inhibitor of transketolase (TK). | |||
T78081 | Farnesyl Pyrophosphate ammonium | Farnesyl diphosphate ammonium | |
Farnesyl Pyrophosphate Ammonium Salt, a 15-carbon isoprenoid derived from the mevalonate (MVA) pathway, functions as a TRPM2 (TRP Channel) agonist, facilitating the opening of TRPM2 channels for ion influx. It serves as ... | |||
T72182 | Combretastatin A1 phosphate | Oxi4503,CA1P,Oxi4503 ; CA1P ; Combretastatin A1 diphosphate,Combretastatin A1 diphosphate | |
Combretastatin A1 phosphate, a potent vascular disruptive agent, exhibits anti-angiogenic effects on tumors and holds potential for research on pancreatic neuroendocrine tumors. | |||
T73983 | Cidofovir diphosphate tri(triethylamine) | ||
Cidofovir diphosphate triethylamine, an active intracellular metabolite of Cidofovir, acts as a selective inhibitor of viral DNA polymerases. It exhibits inhibitory constants (K_i) of 6.6 μM for human cytomegalovirus (HC... | |||
T83817 | Isoguanosine-5'-O-diphosphate sodium | isoGDP | |
Isoguanosine-5'-O-diphosphate (isoGDP), an isomer of GDP and a phosphorylated variant of crotonoside, acts as a mitochondrial ATPase inhibitor, demonstrating effectiveness at a concentration of 3 µM (IC50 = 3 µM). | |||
T73899 | Uridine diphosphate glucuronic acid ammonium | ||
Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium, formed through the enzymatic action of UDP-glucose dehydrogenase, serves as a crucial cofactor in sugar nucleotide biosynthesis. It acts as a pivotal precursor and... | |||
T73824 | Thymidine 3',5'-diphosphate tetrasodium | ||
Thymidine 3',5'-diphosphate tetrasodium (Deoxythymidine 3′,5′-diphosphate tetrasodium) acts as a selective inhibitor targeting staphylococcal nuclease, tudor domain-containing 1 (SND1, a MicroRNA regulatory complex RISC ... | |||
T83785 | 2-Chloroadenosine-5'-O-diphosphate sodium | 2-chloro ADP | |
2-Chloroadenosine-5'-O-diphosphate, a purine nucleotide adenosine 5'diphosphate (ADP) derivative, demonstrates multiple biological activities. It promotes aggregation and inhibits cyclic AMP (cAMP) production, triggered ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1723 | Adenosine 5'-diphosphate | Adenosine diphosphate,adenosine pyrophosphate,ADP | Endogenous Metabolite |
Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase. | |||
T5079 | Adenosine 5'-diphosphate sodium salt | Adenosine-5'-diphosphate trisodium salt,ADP sodium salt | Others , Endogenous Metabolite |
Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is... | |||
T4706 | Uridine-5'-diphosphate disodium salt | UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd | DNA/RNA Synthesis , Endogenous Metabolite , P2Y Receptor |
Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction... | |||
T7210 | Guanosine 5'-diphosphate | GDP | Endogenous Metabolite |
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. | |||
T4972 | 2'-Deoxycytidine-5'-diphosphate trisodium | dCDP | Endogenous Metabolite |
2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription. | |||
T40426 | Cytidine 5'-diphosphate trisodium salt | CDP | Others |
Cytidine 5'-diphosphate trisodium salt (CDP) can produce Cytidine triphosphate for synthesis of DNA and RNA through the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosp... | |||
T83789 | 7-Deazaadenosine-5'-O-diphosphate sodium | 7-CH-ADP,Tubercidin 5’-diphosphate,TuDP | |
7-Deazaadenosine-5'-O-diphosphate, a modified nucleotide and metabolite of tubercidin, is generated through phosphorylation of tubercidin and further undergoes phosphorylation to become the active metabolite 7-deazaadeno... | |||
T3228 | Fosfructose | D-fructose-1,6-diphosphate,Betulanonaprenol,4937-84-2,Diphosphofructose,Fructose 1,6-diphosphate,D-fructofuranose 1,6-bisphosphate,Esafosfan | Others , Endogenous Metabolite |
D-fructose-1,6-diphosphate (D-fructose-1,6-diphosphate), also known as Fosfructose, is a cytoprotective natural sugar phosphate. It functions by promoting anaerobic glycolysis, which generates adenosine triphosphate (ATP... | |||
T39025 | Adenosine 2',5'-diphosphate sodium | ||
Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist with non-selective antagonism at recombinant and human platelet P2X1 receptors. | |||
T19599 | Uridine diphosphate glucose | Others | |
Uridine diphosphate glucose is an important intermediate in several different metabolic pathways and biosynthetic reactions. | |||
T0194 | Chloroquine phosphate | Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs). | |||
T0136 | Citicoline | CDP-Choline,Citicholine,cytidine 5'-diphosphocholine,cytidine diphosphate-choline | Apoptosis , Dopamine Receptor , Endogenous Metabolite |
Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects. | |||
T13264 | Uridine 5'-diphosphate sodium salt | Others | |
Uridine 5'-diphosphate sodium salt is a selective native agonist of the P2Y6 receptor (EC50: 300 nM; pEC50: 6.52), and also is a potent antagonist of P2Y14 (pEC50: 7.28). | |||
T8074 | Esafosfan trisodium | Fosfructose trisodium,D-Fructose-1,6-diphosphate trisodium salt octahydrate,FDP trisodium,Diphosphofructose trisodium | Others , Endogenous Metabolite |
Esafosfan trisodium (FDP trisodium) is a cytoprotective natural sugar phosphate for the potential treatment of sickle cell anemia, cardiovascular ischemia and asthma. It acts by stimulating anaerobic glycolysis which gen... | |||
T40454 | DMAPP | Dimethylallyl diphosphate | |
DMAPP, also known as Dimethylallyl pyrophosphate, is an isoprenoid precursor found in all life forms. It serves as an isomer of isopentenyl pyrophosphate (IPP). | |||
T80989 | Thymidine-5'-diphosphate-L-rhamnose | ||
Thymidine-5'-diphosphate-L-rhamnose disodium, isolated from Occhromonas malhamensis [1], is a chemical compound. | |||
T6535 | Histamine Phosphate | Histamine diphosphate,Histamine acid phosphate | Histamine Receptor |
Histamine Phosphate (Histamine acid phosphate) acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors. | |||
T1208 | Citicoline sodium | Citicoline sodium salt,CDP-choline | Apoptosis , Others , Endogenous Metabolite |
Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demons... | |||
T5288 | Cytidine-5'-triphosphate disodium | CTP,Cytidine 5'-triphosphate (disodium salt) | Others , Endogenous Metabolite |
Cytidine-5'-triphosphate disodium (CTP) is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. Cytidine-5'-triphosphate disodium is used in the synthesis of RNA by RNA polymerases... | |||
T4713 | Phosphorylcholine chloride calcium salt tetrahydrate | Phosphocholine chloride calcium salt tet,CalciuM Phosphorylcholine Tetrahydrate | Others , Endogenous Metabolite |
Phosphorylcholine chloride calcium salt tetrahydrate (Phosphocholine chloride calcium salt tet) is a small haptenic molecule, is found in a wide variety of organisms. Human hepatic tumors undergo an elevation in the conc... | |||
T1609 | NAD+ | Cozymase,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD | NADPH , Endogenous Metabolite |
NAD+ (β-Nicotinamide Adenine Dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous... | |||
TJO2758 | D-Glucuronic acid | Aldehydo-D-Glucuronic Acid | Others , Endogenous Metabolite |
D-Glucuronic acid (Aldehydo-D-Glucuronic Acid) is a carboxylic acid with structural similarity to glucose with detoxifying activity. The xenobiotic metabolism of various substances such as drugs, pollutants, bilirubin, a... | |||
T4758 | 2'-Deoxycytidine | Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine | Endogenous Metabolite |
2'-Deoxycytidine (Deoxyribose cytidine) is one of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base, without a phos... | |||
TN5661 | 1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one | ||
1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one shows strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood. | |||
TN1310 | 6-Hydroxykaempferol 3,6-diglucoside | Others | |
6-Hydroxykaempferol 3,6-di-O-glucoside and 6-hydroxykaempferol 3,6,7-tri-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- ind... | |||
TN2725 | 2',5,6',7-Tetrahydroxyflavanone | Others | |
(2S)-2',5,6',7-Tetrahydroxyflavanone can inhibit the lipid peroxide formation induced by adenosine diphosphate and reduced nicotinamide adenine dinucleotide phosphate in rat liver homogenate. | |||
TN1309 | 6-Hydroxykaempferol-3,6,7-triglucoside | Others | |
6-Hydroxykaempferol 3,6,7-tri-O-glucoside and 6-hydroxykaempferol 3,6-di-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- ind... | |||
TN4664 | Norarmepavine | Others | |
N-norarmepavine shows significant cytotoxic activities against HL-60 carcinoma cell line with inhibitory ratios of 51.43% at concentration of 1 x 10(-5) M. Norarmepavine shows inhibition against Trypanosoma cruzi. D-(+)-... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00477 | IDI2 Protein, Human, Recombinant (His) | Human | E. coli |
IDI2 Protein, Human, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 29 kDa. Accession number: Q9BXS1 | |||
TMPY-00330 | GGPS1 Protein, Human, Recombinant (His) | Human | HEK293 |
GGPS1 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 36.3 kDa. Accession number: A0A024R3R2 | |||
TMPY-00451 | FDPS Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions... | |||
TMPY-00116 | MTH1 Protein, Human, Recombinant (His) | Human | E. coli |
NUDT1 (Nudix Hydrolase 1) is a Protein Coding gene. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates to monophosphates, thereby preventing misincorporation. The NUDT1... | |||
TMPY-02278 | NUDT2 Protein, Human, Recombinant (His) | Human | E. coli |
NUDT2 Protein, Human, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 18.3 kDa. Accession number: P50583 | |||
TMPJ-00937 | RRM2 Protein, Human, Recombinant (His) | Human | Human Cells |
Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. S... | |||
TMPY-03849 | NUDT5 Protein, Human, Recombinant (His) | Human | E. coli |
NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene. This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphos... | |||
TMPY-04467 | NME1 Protein, Human, Recombinant (His) | Human | E. coli |
NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the inter... | |||
TMPH-01631 | DCP2 Protein, Human, Recombinant (His) | Human | E. coli |
Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the ... | |||
TMPH-00589 | SpoT Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme cataly... | |||
TMPY-03287 | RRM1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesi... | |||
TMPH-03585 | Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His) | Staphylococcus haemolyticus | E. coli |
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | |||
TMPY-02654 | FDPS Protein, Human, Recombinant (His) | Human | E. coli |
Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions... | |||
TMPH-02388 | PyrE Protein, Laribacter hongkongensis, Recombinant (His & SUMO) | Laribacter hongkongensis | E. coli |
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | |||
TMPH-01861 | LHPP Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency. | |||
TMPH-02137 | FDFT1 Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate in... | |||
TMPH-02964 | UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. A... | |||
TMPJ-01262 | UPRT Protein, Human, Recombinant (His) | Human | E. coli |
UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion o... | |||
TMPH-01323 | FDPS Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP ... | |||
TMPH-00673 | NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His) | E. coli | E. coli |
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosph... | |||
TMPY-04767 | PMVK Protein, Human, Recombinant (His) | Human | E. coli |
PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level a... | |||
TMPH-00713 | Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Can form linear polymers of orthophosphate with chain lengths up to 1000 or more. Can use GTP instead of ATP,... | |||
TMPJ-01308 | ITPase Protein, Human, Recombinant (His) | Human | E. coli |
Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphat... | |||
TMPJ-01406 | MOB4 Protein, Human, Recombinant (His) | Human | E. coli |
MOB-Like Protein Phocein is a member of the MOB1/Phocein Family. MOB-Like Protein Phocein is associated with membranes and the Golgi stacks. It is present in the cytosol, where it behaves as a protein complex. It has bee... | |||
TMPY-04480 | UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), re... | |||
TMPY-04762 | CKM Protein, Human, Recombinant (His) | Human | E. coli |
CKM, also known as CK-MM, is mainly expressed in skeletal muscle. As the primary CK isoenzyme, it also can be detected in heart muscle. CKM is a subunit of creatine kinase (CK). CK is an enzyme expressed by various tissu... | |||
TMPJ-00905 | DTYMK Protein, Human, Recombinant (His) | Human | Human Cells |
Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolis... | |||
TMPJ-00660 | IMPase2 Protein, Human, Recombinant (His) | Human | E. coli |
Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylr... | |||
TMPH-03236 | Alkaline phosphatase/ALPL Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
Alkaline phosphatase that metabolizes various phosphate compounds and plays a key role in skeletal mineralization and adaptive thermogenesis. Has broad substrate specificity and can hydrolyze a considerable variety of co... | |||
TMPY-02975 | CANT1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
CANT1(calcium activated nucleotidase 1) belongs to the apyrase family. Apyrase is a calcium-activated plasma membrane-bound enzyme (magnesium can also activate it) (EC 3.6.1.5) that catalyses the hydrolysis of ATP to yie... | |||
TMPY-02710 | CANT1 Protein, Human, Recombinant (His) | Human | HEK293 |
CANT1(calcium activated nucleotidase 1) belongs to the apyrase family. Apyrase is a calcium-activated plasma membrane-bound enzyme (magnesium can also activate it) (EC 3.6.1.5) that catalyses the hydrolysis of ATP to yie... | |||
TMPH-02501 | FUT7 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal alpha2,3 sialylated lactosamine unit of a glycoprotein or a glycolipid-linked sialopolylact... |
Cat No. | Product Name | ||
---|---|---|---|
L1710 | Anti-COVID-19 Compound Library | 1160 compounds | |
A unique collection of 1160 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents; |