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Search Result

Search Results for " antipyretic "

Targets

Others

80

Compounds

13

Natural Products

Cat No. Product Name Synonyms Targets
T5424 Etosalamide Ethosalamide Others
Etosalamide (Ethosalamide) is an antipyretic and analgesics agent.
T0734 Antipyrine Phenazone,Phenazon COX
Antipyrine (Phenazone), an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver.
T0778 Phenacetin Acetophenetidin COX
Phenacetin (Acetophenetidin) is a phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market.
T10152 4-Methylamino antipyrine COX , Drug Metabolite
4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methylamino antipyrine has analgesic, antipyretic, and relativel...
T0456 Cinchophen Cinconal COX
Cinchophen (Cinconal), an analgesic drug, is utilized in treating gout.
T1191L Metamizole sodium Analgin,Dipyron COX
Metamizole sodium (Analgin) is a drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE.
T27635 Isoxepac Olopatadine USP Related Compound C Others
Isoxepac (Olopatadine USP Related Compound C) is a non-steroidal anti-antiphlogistic agent and analgesic.
T0859 Fenbufen CL-82204,Lederfen ATPase , Caspase , COX
Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractur...
T0448 (S)-(+)-Ibuprofen Dexibuprofen,(S)-Ibuprofen BCL , Thrombin , Cysteine Protease , COX , PPAR
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
T19679 Benoxaprofen NSC 299582,LY-90459,Benoxaphen. Compound 90459 COX
Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.
T0005 Aspirin Acetylsalicylate,Acetylsalicylic Acid,ASA Mitophagy , Virus Protease , COX , Autophagy
Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel...
T12533 Piperylone PR66 Others
Piperylone (PR66) has anti-spasmodic, analgesic, anti-inflammatory and antipyretic activities.
T3608 Carbasalate calcium Rheomin,Omegin,Alcacyl,Iromin,Solupsan,Carbasalate Calcium Platelet aggregation
Carbasalate calcium (Rheomin) is an analgesic, antipyretic, and anti-inflammatory drug, as well as a platelet aggregation inhibitor.
T16950 Sudoxicam 4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide COX
Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema, and antipyretic properties.
T19641 Epirizole DA 398,Mepirizole,DA398,Mebron,Methopyrimazole,Dalex,DA-398 Others
Epirizole (Mebron) shows antipyretic, analgesic, and anti-inflammatory activity and can be used in studies about chronic rheumatoid arthritis.
T6687 Suprofen Maldocil,Suprol,TN-762,Profenal COX , PGE Synthase
Suprofen (Suprol) is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.
T0442 Bucetin 3-Hydroxy-p-butyrophenetidide Others
Bucetin (3-Hydroxy-p-butyrophenetidide) is a pharmaceutical drug that acts as an analgesic and antipyretic. Bucetin was withdrawn from use in 1986 due to renal toxicity.
T22307 Diclofenac Epolamine diclofenac hydroxyethylpyrrolidine,DHEP,DIEP Others
Diclofenac Epolamine (DHEP) is a non-steroidal anti-inflammatory agent (NSAID) with analgesic and antipyretic actions.
T22346 Indomethacin sodium hydrate Indometacin Sodium COX
Indomethacin Sodium is the sodium salt of indomethacin, which is a non-selective, competitive, and reversible, inhibitor of cyclooxygenases 1 and 2 with analgesic-antipyretic, anti-inflammatory, and tocolytic effects.
T0890 Mefenamic acid CN-35355,CI 473 COX
Mefenamic acid (CN-35355) is a non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
T19672 Amtolmetin guacil MED 15,MED15,ST679,ST-679,ST 679,MED-15 COX
Amtolmetin guacil (ST-679) inhibits prostaglandin synthesis and cyclooxygenase. Amtolmetin guacil has similar NSAID properties like tolmetin with additional analgesic, antipyretic, and gastroprotective properties.
T1209 Flunixin meglumine Banamine,Finadyne,Flunixin meglumin COX
Flunixin meglumine (Banamine) is an effective inhibitor of the enzyme cyclooxygenase with anti-inflammatory and antipyretic activity.
T7238 2-Acetamidophenol Orthocetamol
2-Acetamidophenol (Orthocetamol) has analgesic and antipyretic effects. 2-Acetamidophenol is an isomer of Paracetamol (4-acetamidophenol).
T0058 2-Ethoxybenzamide Ethenzamide,Anovigam COX
2-Ethoxybenzamide (Anovigam) is white or almost-white crystalline powder. Almost odorless. Tasteless. It is widely used as an antipyretic anodyne.
T1133 Nimesulide R805 COX
Nimesulide (R805) is a relatively COX-2 selective inhibitor with analgesic and antipyretic properties.
T5010 Propyphenazone Isopropylantipyrine,Propyphenazone (4-Isopropylantipyrine),Isopropylphenazone,4-Isopropylantipyrine,Isopropyrine COX
Propyphenazone (4-Isopropylantipyrine), a pyrazolone derivative, exhibits anti-inflammatory, analgesic, and antipyretic properties and acts as a precursor for prodrugs and selective cyclooxygenase-2 inhibitors.
T1586 Tenoxicam Ro-12-0068,Tenoxicamum,Mobiflex,Tilcotil COX
Tenoxicam (Tilcotil), an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
T0867 Bufexamac Bufexamic acid COX , HDAC
Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.
T1582L Naproxen sodium Miranax,Anaprox,RS-3650,Naprelan COX , Autophagy
Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.
T0858 Flufenamic acid Arlef,Nichisedan,Achless Potassium Channel , Calcium Channel , Chloride channel , COX , AMPK , Parasite
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically.
T3276 Benorilate Benortan,Benoral,Salipran,Benorylate Prostaglandin Receptor
Benorilate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.
T1191 Metamizole sodium hydrate Sulpyrine,Analgin,Dipyron hydrate COX
Metamizole sodium hydrate (Analgin) is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX). Target: COX Dipyrone is a potent analgesic and antipyretic drug that has been used clinically for...
T1582 Naproxen (S)-Naproxen COX , Autophagy
Naproxen ((S)-Naproxen) is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities.
T27312 Fentiazac Donorest,Flogene,BR-700 Others
Fentiazac（BR-700） is an orally active nonsteroidal alkanoic acid derivative with significant analgesic, anti-inflammatory, and antipyretic activity.Fentiazac is used in the study of inflammatory diseases such as rheumato...
T1212 Ketorolac tromethamine salt Acular LS,Toradol,Ketorolac tris salt,Acular COX
Ketorolac tromethamine salt (Ketorolac tris salt) non-selective inhibits the enzymes cyclooxygenase 1 (COX-1) and COX-2with anti-inflammatory, analgesic, and antipyretic activities.
T1325 Carprofen Ridamyl,Imadyl,Rimadyl FAAH , COX , Autophagy
Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.
T8807 Benzydamine Others
Benzydamine is a benzyl-indazole having analgesic, antipyretic, and anti-inflammatory effects. Benzydamine is used to reduce post-surgical and post-traumatic pain and edema and to promote healing.
T0260 Meclofenamic acid sodium Meclofenamate Sodium,Movens,Meclomen,Meclonax Gap Junction Protein , COX
Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
T0914 Metacetamol 3-Acetamidophenol Others
Metacetamol (3-Acetamidophenol) is a derivative of acetaminophen, a non-toxic regional isomer of acetaminophen. It is an over-the-counter analgesic and antipyretic and is also used as an organic synthesis intermediate.
TP2212L A-MSH, amide Acetate(581-05-5 free base) Melanocortin Receptor
a-MSH, amide Acetate as an endogenous neuropeptide. It is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelano...
T0498 Salsalate Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171 Reactive Oxygen Species , COX
Salsalate (Sasapyrine) is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities.
T0855 (R)-Naproxen COX
(R)-Naproxen, an anti-inflammatory agent, has antipyretic and analgesic properties. Both the acid and its sodium salt are used in the therapy of acute gout or dysmenorrhea, musculoskeletal disorders, rheumatoid arthritis...
T1432 Phenylbutazone Butazolidine COX
Phenylbutazone (Butazolidine) is a butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ankylosing spondylitis, rheumatoid arthritis, and reactive arthri...
T1555 Diclofenac sodium GP 45840 Apoptosis , COX
Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
T0291 Flurbiprofen dl-Flurbiprofen Apoptosis , COX , MRP
Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
T1002 Etodolac Ultradol,AY-24236,Etodolic acid,Lodine Retinoid Receptor , COX
Etodolac (AY-24236) inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. Etodolac is a pyranocarboxylic ...
T1394 Ibuprofen Brufen,(±)-Ibuprofe,Motrin,Advil COX
Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu...
T15181 DuP-697 COX
DuP-697 is an irreversible and specific inhibitor of COX-2 with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1. DuP-697 shows antiproliferative activity with an IC50 of 42.8 nM. DuP-697 exhibits antiangiogenic...
T0839 Ketoprofen RP-19583 Apoptosis , COX , MRP
Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenas...
T1574 Etoricoxib Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine COX
Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenas...

Compounds

Etosalamide
T5424
Synonym: Ethosalamide
Target: Others
Antipyrine
T0734
Synonym: Phenazone,Phenazon
Target: COX
Phenacetin
T0778
Synonym: Acetophenetidin
Target: COX
4-Methylamino antipyrine
T10152
Synonym:
Target: COX, Drug Metabolite
Cinchophen
T0456
Synonym: Cinconal
Target: COX
Metamizole sodium
T1191L
Synonym: Analgin,Dipyron
Target: COX
Isoxepac
T27635
Synonym: Olopatadine USP Related Compound C
Target: Others
Fenbufen
T0859
Synonym: CL-82204,Lederfen
Target: ATPase, Caspase, COX
(S)-(+)-Ibuprofen
T0448
Synonym: Dexibuprofen,(S)-Ibuprofen
Target: BCL, Thrombin, Cysteine Protease, COX, PPAR
Benoxaprofen
T19679
Synonym: NSC 299582,LY-90459,Benoxaphen. Compound 90459
Target: COX
Aspirin
T0005
Synonym: Acetylsalicylate,Acetylsalicylic Acid,ASA
Target: Mitophagy, Virus Protease, COX, Autophagy
Piperylone
T12533
Synonym: PR66
Target: Others
Carbasalate calcium
T3608
Synonym: Rheomin,Omegin,Alcacyl,Iromin,Solupsan,Carbasalate Calcium
Target: Platelet aggregation
Sudoxicam
T16950
Synonym: 4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
Target: COX
Epirizole
T19641
Synonym: DA 398,Mepirizole,DA398,Mebron,Methopyrimazole,Dalex,DA-398
Target: Others
Suprofen
T6687
Synonym: Maldocil,Suprol,TN-762,Profenal
Target: COX, PGE Synthase
Bucetin
T0442
Synonym: 3-Hydroxy-p-butyrophenetidide
Target: Others
Diclofenac Epolamine
T22307
Synonym: diclofenac hydroxyethylpyrrolidine,DHEP,DIEP
Target: Others
Indomethacin sodium hydrate
T22346
Synonym: Indometacin Sodium
Target: COX
Mefenamic acid
T0890
Synonym: CN-35355,CI 473
Target: COX
Amtolmetin guacil
T19672
Synonym: MED 15,MED15,ST679,ST-679,ST 679,MED-15
Target: COX
Flunixin meglumine
T1209
Synonym: Banamine,Finadyne,Flunixin meglumin
Target: COX
2-Acetamidophenol
T7238
Synonym: Orthocetamol
Target:
2-Ethoxybenzamide
T0058
Synonym: Ethenzamide,Anovigam
Target: COX
Nimesulide
T1133
Synonym: R805
Target: COX
Propyphenazone
T5010
Synonym: Isopropylantipyrine,Propyphenazone (4-Isopropylantipyrine),Isopropylphenazone,4-Isopropylantipyrine,Isopropyrine
Target: COX
Tenoxicam
T1586
Synonym: Ro-12-0068,Tenoxicamum,Mobiflex,Tilcotil
Target: COX
Bufexamac
T0867
Synonym: Bufexamic acid
Target: COX, HDAC
Naproxen sodium
T1582L
Synonym: Miranax,Anaprox,RS-3650,Naprelan
Target: COX, Autophagy
Flufenamic acid
T0858
Synonym: Arlef,Nichisedan,Achless
Target: Potassium Channel, Calcium Channel, Chloride channel, COX, AMPK, Parasite
Benorilate
T3276
Synonym: Benortan,Benoral,Salipran,Benorylate
Target: Prostaglandin Receptor
Metamizole sodium hydrate
T1191
Synonym: Sulpyrine,Analgin,Dipyron hydrate
Target: COX
Naproxen
T1582
Synonym: (S)-Naproxen
Target: COX, Autophagy
Fentiazac
T27312
Synonym: Donorest,Flogene,BR-700
Target: Others
Ketorolac tromethamine salt
T1212
Synonym: Acular LS,Toradol,Ketorolac tris salt,Acular
Target: COX
Carprofen
T1325
Synonym: Ridamyl,Imadyl,Rimadyl
Target: FAAH, COX, Autophagy
Benzydamine
T8807
Synonym:
Target: Others
Meclofenamic acid sodium
T0260
Synonym: Meclofenamate Sodium,Movens,Meclomen,Meclonax
Target: Gap Junction Protein, COX
Metacetamol
T0914
Synonym: 3-Acetamidophenol
Target: Others
a-MSH, amide Acetate(581-05-5 free base)
TP2212L
Synonym:
Target: Melanocortin Receptor
Salsalate
T0498
Synonym: Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171
Target: Reactive Oxygen Species, COX
(R)-Naproxen
T0855
Synonym:
Target: COX
Phenylbutazone
T1432
Synonym: Butazolidine
Target: COX
Diclofenac sodium
T1555
Synonym: GP 45840
Target: Apoptosis, COX
Flurbiprofen
T0291
Synonym: dl-Flurbiprofen
Target: Apoptosis, COX, MRP
Etodolac
T1002
Synonym: Ultradol,AY-24236,Etodolic acid,Lodine
Target: Retinoid Receptor, COX
Ibuprofen
T1394
Synonym: Brufen,(±)-Ibuprofe,Motrin,Advil
Target: COX
DuP-697
T15181
Synonym:
Target: COX
Ketoprofen
T0839
Synonym: RP-19583
Target: Apoptosis, COX, MRP
Etoricoxib
T1574
Synonym: Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine
Target: COX
1 2
Cat No. Product Name Synonyms Targets
T6S1435 Notopterol Apoptosis , Others
1. Notopterol induces apoptosis and inhibits cell cycle-specific.
TN1650 Friedelin P450 , NOS , Caspase , Prostaglandin Receptor
Friedelin possesses antioxidant, gastroprotective, anti-diarrhoeal, liver protective, anti-inflammatory, analgesic and antipyretic activities.
T4842 1H-pyrazole 1,2-Diazole,Pyrazole Others , Endogenous Metabolite
1H-pyrazole (1,2-Diazole), is a versatile building block, with a vast applications in organic synthesis. The derivatives of Pyrazole are used in medicine, for their analgesic, anti-inflammatory, antipyretic, antiarrhythm...
T0065 Acetaminophen 4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol COX , Endogenous Metabolite , Histone Acetyltransferase
Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7/25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity.
T0004 Salicylamide Salamide,2-Hydroxybenzamide COX
Salicylamide (2-Hydroxybenzamide) is an over-the-counter drug with analgesic and antipyretic properties, which has similar medicinal properties to aspirin. In the over-the-counter pain remedies, Salicylamide is used in c...
TN1215 (2S)-2'-Methoxykurarinone 2'-Methoxykurarinone,2'-O-Methylkurarinone Akt , Antifection
(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone inhibits osteo...
T5592 Acetosyringone Acetosyringenin Others
Acetosyringone (Acetosyringenin)(AS) is a phenol secreted by wounded plant tissues.Acetosyringone is a phenolic natural product with analgesic, antipyretic and anti-inflammatory actions.
T5S1708 Dendrobine Others , Influenza Virus
1. Dendrobine has a slight but demonstrable analgesic and antipyretic action. 2. Dendrobine produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the blood pressure. 3. Dendrobine on the ele...
T1468 Lornoxicam Ro 13-9297,Chlortenoxicam,TS110 COX , Endogenous Metabolite
Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam co...
T6S1699 Shogaol [6]-Shogaol,6-Shogaol Lipoxygenase , Autophagy
1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f...
T6S1684 8-Gingerol Antioxidant , Antibacterial , TRP/TRPV Channel
1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic...
T4S1551 Cinnamaldehyde Cinnamic Aldehyde HIF
1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the express...
T82533 Donasine
Donasine, an indole alkaloid naturally derived from the rhizomes of Arundo donax L. [1], exhibits antipyretic properties.

Natural Products

Notopterol
T6S1435
Synonym:
Target: Apoptosis, Others
Friedelin
TN1650
Synonym:
Target: P450, NOS, Caspase, Prostaglandin Receptor
1H-pyrazole
T4842
Synonym: 1,2-Diazole,Pyrazole
Target: Others, Endogenous Metabolite
Acetaminophen
T0065
Synonym: 4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol
Target: COX, Endogenous Metabolite, Histone Acetyltransferase
Salicylamide
T0004
Synonym: Salamide,2-Hydroxybenzamide
Target: COX
(2S)-2'-Methoxykurarinone
TN1215
Synonym: 2'-Methoxykurarinone,2'-O-Methylkurarinone
Target: Akt, Antifection
Acetosyringone
T5592
Synonym: Acetosyringenin
Target: Others
Dendrobine
T5S1708
Synonym:
Target: Others, Influenza Virus
Lornoxicam
T1468
Synonym: Ro 13-9297,Chlortenoxicam,TS110
Target: COX, Endogenous Metabolite
Shogaol
T6S1699
Synonym: [6]-Shogaol,6-Shogaol
Target: Lipoxygenase, Autophagy
8-Gingerol
T6S1684
Synonym:
Target: Antioxidant, Antibacterial, TRP/TRPV Channel
Cinnamaldehyde
T4S1551
Synonym: Cinnamic Aldehyde
Target: HIF
Donasine
T82533
Synonym:
Target:
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