ace inhibitor

Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.

Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.

Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.

Cilazapril Monohydrate (Justor) is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.

Moveltipril calcium salt is an ACE inhibitor.

Benazepril hydrochloride (CGS 14824A HCl) is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension. Benazepril hydrochloride is associated with a low rate of transient serum aminotransferase elevations and has been linked to rare instances of acute liver injury.

Lisinopril dihydrate (MK-521) is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.

Quinapril hydrochloride (PD-109452-2) is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril hydrochloride is associated with a low rate of transient serum aminotransferase elevations, but has yet to be linked to instances of acute liver injury.

Captopril (SA333) is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of arterial blood pressure.

Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, Perindopril erbumine (S9490-3) is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue.

Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to its active metabolite fosinoprilat.

Ramipril (Altace) is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat.

Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinapic acid with antioxidant role protects cardiac cells and its functions from I/R induced oxidative stress. Sinapic acid is a potentially useful agent for the protection against liver fibrosis and cirrhosis. Sinapic acid prevents the alterations in the levels of lipids and lipoproteins by virtue of its anti-lipidaemic effect in isoproterenol induced myocardial infarcted rats. Sinapic acid ameliorates hyperglycemia through PLC-PKC signals to enhance the glucose utilization in diabetic rats.

Enalapril Maleate (MK-421 Maleate), an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy.

Temocapril is an inhibitor of tyrosine kinase.

Vicenin 3 is an inhibitor of angiotensin-converting enzyme (ACE; IC50: 46.91 μM) from the aerial parts of Desmodium styracifolium.

Diltiazem malate is an ACE inhibitor and non-dihydropyridine calcium channel blocker used in the treatment of hypertension.

Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.

Enalapril-D5 maleate is deuterium labeled Enalapril maleate (TMSM-1101), which is an angiotensin converting enzyme (ACE) inhibitor.

Enalaprilat-D5 sodium is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.

Enalaprilat-D5 is the deuterium labeled Enalaprilat (T6340L), which is an angiotensin-converting enzyme (ACE) inhibitor.

Diminazene is a trypanocidal agent.

Imidaprilate, an active metabolite of TA-6366, is a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM) used in hypertension research.

Rentiapril is an orally active inhibitor of angiotensin converting enzyme (ACE), with antihypertensive activity.