gdp — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T74041	GDP-L-fucose		Endogenous Metabolite
	GDP-L-fucose is a nucleotide sugar widely found in fungi and plants and is involved in both the slave and secondary remedial metabolic pathways.		Endogenous Metabolite
T7210	Guanosine 5'-diphosphate	GDP	Endogenous Metabolite
	Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.		Endogenous Metabolite
T7606	Guanosine 5'-diphosphate disodium salt	5'-GDP-Na2	Endogenous Metabolite
	Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway.		Endogenous Metabolite
T11382	GDP-α-D-mannose disodium		Others
	GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM).GDP-α-D-mannose disodium is the donor substrate for mannosy...		Others
T11383	GDP366		Survivin
	GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.		Survivin
T74042	GDP-L-fucose disodium
	GDP-L-fucose disodium, a nucleotide sugar, serves as a crucial substrate for fucose oligosaccharides biosynthesis by providing the fucose moiety. Its formation follows two metabolic pathways: the primary de novo pathway ...
T72120	Guanosine 5'-diphosphate sodium	GDP sodium
	Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate known for activating the adenosine 5'-triphosphate-sensitive K+ channel and serving as a potential iron mobilizer by inhibiting the hepcidin-ferroportin i...
T65209	GDP-D-mannose disodium
	GDP-D-mannose disodium is a natural product for research related to life sciences and the catalog number is T65209.
T8684	Sotorasib	AMG-510	Ras
	Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib ...		Ras
T8369	Adagrasib	MRTX849	Ras
	Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib ...		Ras
T31919	Gdpflrfamide	Gly-asp-pro-phe-leu-arg-phe-amide
	Gdpflrfamide is a neuropeptide that existed in the snail Lymnaea stagnalis.
T9198	SCH54292		Ras
	SCH-54292 is a GDP exchange inhibitor.		Ras
T8930	CID44216842	KUC103479N-02	CDK , Ras
	CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT...		CDK , Ras
T40192	DGTP	2'-Deoxyguanosine-5'-triphosphate	Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.		Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
T69529	BI-0474		Ras
	BI-0474 is a potent KRASG12C inhibitor that inhibits GDP-KRAS::SOS1 protein-protein interactions with an IC50 value of 7.0 nM.BI-0474 exhibits significant antiproliferative activity against NCI-H358 cells harboring the G...		Ras
T13983	0990CL		cAMP , Others
	0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± in GDP-bound state, and can block α2AR mediated cAMP regulation. In the cell model, low concentration of 0990CL cou...		cAMP , Others
T38170	RMC-0331	RM-023	Raf
	RMC-0331 (RM-023) is an orally available and potent SOS1 inhibitor.RMC-0331 has potential anticancer activity, blocking RAS activation by disrupting RAS-SOS1 interactions.		Raf
T7414	ARS-853		Apoptosis , Raf , Ras
	ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells		Apoptosis , Raf , Ras
T15485	HJC0197		cAMP , Ras
	HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2).		cAMP , Ras
T64537	Guanosine 5′-diphospho-β-L-fucose sodium salt
	GDP-β-L-fucose is a metabolite in plant and animal. It used for microbe agglutination assay and agglutination inhibition assay. GDP-β-L-fucose is formed by the oxidation-reduction and epimerization of GDP-R-D-mannose in ...