T2434 |
LY 303511
|
154447-38-8
|
99.91%
|
|
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
|
T79211 |
MTOR inhibitor-11
|
|
98%
|
|
mTOR inhibitor-11 (Compound 9) is a brain-penetrant compound capable of inhibiting mTOR with an IC50 of 21 nM for pS6. It also exhibits inhibitory activity again...
|
T79212 |
MTOR inhibitor-12
|
|
98%
|
|
mTOR inhibitor-12 (Compound 11), a selective, brain-penetrant mTOR inhibitor, exhibits no genotoxicity risk and is utilized in research pertaining to central ner...
|
T80546 |
Thioether-cyclized helix B peptide, CHBP
|
1453840-35-1
|
98%
|
|
Thioether-cyclized helix B peptide (CHBP) enhances metabolic stability and exerts renoprotective effects by promoting autophagy through the inhibition of mTOR C1...
|
T80547 |
Thioether-cyclized helix B peptide, CHBP TFA
|
|
98%
|
|
Thioether-cyclized helix B peptide, CHBP (TFA), is the trifluoroacetic (TFA) salt of CHBP. This form enhances metabolic stability and exhibits renoprotective eff...
|
T81743 |
MTORC1-IN-1
|
|
98%
|
|
mTORC1-IN-1 (T1), a rapamycin homologue (rapalog) and selective inhibitor of mTORC1, controls cell growth and metabolism, with implications in various diseases s...
|
T81744 |
MTOR inhibitor-14
|
|
98%
|
|
mTOR Inhibitor-14 (compound 14c) is a potent inhibitor of mTOR with minimal inhibition of CYP2C8 and has demonstrated the capability to inhibit tumor growth [1]....
|
T11328 |
FT-1518
|
1313026-58-2
|
98%
|
|
FT-1518 ,exhibits antitumor activity, is a new generation selective, potent and oral bioavailable mTORC1 and mTORC2 inhibitor.
|
TN3310 |
9,9'-Di-O-(E)-feruloylsecoisolariciresinol
|
56973-66-1
|
98%
|
|
1,4-O-Diferuloylsecoisolariciresinol(9,9'-Di-O-(E)-feruloylsecoisolariciresinol),and pierreione B, two novel inhibitors of mTOR signaling, have strong anticancer...
|
TN4788 |
Pierreione B
|
1292766-21-2
|
98%
|
|
Pierreione B is an inhibitor of mTOR signaling with strong anticancer activity. Pierreione A and Pierreione B demonstrate solid tumor selectivity with minimal cy...
|
T11742L |
K-7174 dihydrochloride
|
191089-60-8
|
98%
|
|
K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α...
|
TN2328 |
Zeylenone
|
193410-84-3
|
98%
|
|
Zeylenone, a cyclohexene oxide from Uvaria grandiflora, has antitumour and antiproliferative activity, inhibiting cervical cancer cell proliferation and inducing...
|
TN4382 |
Kazinol A
|
99624-28-9
|
98%
|
|
Kazinol A shows strong inhibition of arachidonic acid (AA)-induced platelet aggregation. It also exhibits potent inhibition with IC50 values ranging 0.6-164 M ag...
|
T6346 |
WYE-132
|
1144068-46-1
|
98%
|
|
WYE-125132 (WYE-132 (WYE-125132)) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related...
|
TN5050 |
Sprengerinin C
|
88861-91-0
|
98%
|
|
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can st...
|
T12124 |
MTOR inhibitor-2
|
2219323-96-1
|
98%
|
|
mTOR inhibitor-2 is an inhibitor of selective and oral mTOR (IC50 of 7 nM).
|
T77629 |
FD274
|
2641899-38-7
|
98%
|
|
FD274 is a potent dual PI3K/mTOR inhibitor with inhibitory effects on PI3Kα/β/γ/δ and mTOR, with IC50s of 0.65 nM, 1.57 nM, 0.65 nM, 0.42 nM, and 2.03 nM, respec...
|
TN4356 |
Jolkinolide A
|
37905-07-0
|
98%
|
|
Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly in...
|
TN4213 |
Hirsutenone
|
41137-87-5
|
98%
|
|
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid pero...
|
TN1245 |
3-Deoxysappanchalcone
|
112408-67-0
|
98%
|
|
3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level.
|