molecule library

A unique collection of xnum calcium channel blockers and agonists for high throughput and high content screening;

Offers xnum small molecules that enhance gene editing efficiency, suitable for high-throughput screening (HTS) and high-content screening (HCS);

A unique collection of xnum GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research;

xnum well-chosen unique AMPK-targeted small molecules;

A unique collection of xnum compounds targeting NF-κB signaling for high throughput screening and high content screening;

A unique collection of xnum DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);

A unique collection of xnum compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);

A unique collection of xnum approved drugs for high throughput screening (HTS) and high content screening (HCS);

A unique collection of xnum kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.

A unique collection of xnum anticancer drugs for high throughput screening (HTS) and high content screening (HCS);

A collection of xnum selected human endogenous metabolites for high throughput and high content screening.

A unique collection of xnum compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).

A collection of xnum small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification;

A unique collection of xnum FDA approved drugs for high throughput screening (HTS) and high content screening (HCS);

A unique collection of xnum promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;

A unique collection of xnum rare natural products, which can be used for high throughput screening (HTS) and high content screening (HCS);

A unique collection of xnum annotated bioactive compounds with clear targets, suitable for phenotypic screening;

The library consists of 3745 members belonging 22 scaffolds (average 180 compounds per scaffold).

The unparalleled chemical diversity of natural products makes them an ideal choice for screening active small molecules. Natural products is always a significant source in drug discovery. According to authoritative statistics, 79 out of 99 small molecule anticancer drugs have been successfully developed based on natural products since 1981. Natural products have demonstrated successful modulation of isolated but crucial targets, especially in antimicrobial targets and protein interactions. Many researchers consider natural products and their derivatives as unique tools for studying and manipulating protein function. The Drug-like Natural Compound Library comprises 522 novel molecules, serving as a complement to the L6000 Natural Product Library. This library enhances the probability of successful drug screening, making it an excellent tool for lead compound discovery.

A unique collection of xnum EMA-approved drugs for high throughput screening (HTS) and high content screening (HCS);

A unique collection of xnum compounds targeting MAPK signaling for drug discovery in MAPK related diseases;

A unique collection of xnum nuclear receptor signaling targeted compounds for high throughput and high content screening;

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes. Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases. TargetMol has collected xnum compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

A unique collection of xnum approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);