Search Result

Search Results for " autophosphorylation "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T39185	Pp60 (v-SRC) Autophosphorylation Site, Phosphorylated	pp60 (v-SRC) Autophosphorylation Site, Phosphorylated
	pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide derived from an EGFR substrate. It serves as a valuable tool for quantifying phosphorylated substrates in screening EGFR Kinase inhibitors...
T21761	HNMPA		IGF-1R
	HNMPA is a membrane impermeable inhibitor of insulin receptor tyrosine kinase. HNMPA inhibits tyrosine and serine autophosphorylation by the human insulin receptor. HNMPA exhibits no effect on cyclic AMP-dependent prote...		IGF-1R
T36287	Pirtobrutinib		BTK
	Pirtobrutinib (LOXO-305) is an advanced BTK inhibitor that displays high selectivity and operates through a non-covalent mechanism. This compound effectively inhibits various BTK C481 substitution mutations, leading to t...		BTK
T14765	BOS-172722		Kinesin
	BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).		Kinesin
T14137	AG 1295		PDGFR
	AG 1295, a selective inhibitor of platelet-derived growth factor receptor (PDGFR) tyrosine-kinase, effectively halts PDGFR autophosphorylation without impacting the autophosphorylation of the EGF receptor[1][2][3][4].		PDGFR
T1770	GNE-9605		LRRK2
	GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).		LRRK2
T2694	KN-62		CaMK , P2X Receptor , Autophagy
	KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.		CaMK , P2X Receptor , Autophagy
T22396	PF-6274484	PF 6274484	EGFR
	PF-6274484, a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM, inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells with IC50 of 5.8 nM and ...		EGFR
T4014	CP-724714	CP724714,CP 724714	Apoptosis , EGFR
	CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2, c-Met etc.		Apoptosis , EGFR
T7673	ATH686	ATH 686	Apoptosis , FLT
	ATH686 is an potent and selective Inhibitor of FLT3.		Apoptosis , FLT
T2085	PQ401	IGF-1R Inhibitor II	Apoptosis , IGF-1R
	PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).		Apoptosis , IGF-1R
T5168	EGFR-IN-12	EGFR Inhibitor	Apoptosis , EGFR
	EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.		Apoptosis , EGFR
T38562	AKN-028		FLT
	AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.		FLT
T3058	(Z)-SMI-4a	TCS PIM-1 4a,SMI-4a	Pim
	(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.		Pim
T9564	IRE1α kinase-IN-1		IRE1
	IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosph...		IRE1
T8330	BIO-013077-01		TGF-beta/Smad
	BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.		TGF-beta/Smad
T8976	PD-089828		EGFR , FGFR , PDGFR , Src
	PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...		EGFR , FGFR , PDGFR , Src
T2655	CEP-37440	CEP37440	FAK , ALK
	CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).		FAK , ALK
T4327	Prexasertib dihydrochloride	LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368	Apoptosis , Chk , S6 Kinase
	Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively.		Apoptosis , Chk , S6 Kinase
T23127	PD-161570	PD 161570	EGFR , FGFR , PDGFR , Src
	PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...		EGFR , FGFR , PDGFR , Src
T4205	AG-494	Tyrphostin AG-494,AG 494,Tyrphostin B48	EGFR , CDK
	AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.		EGFR , CDK
T4310	Prexasertib	LY2606368	Apoptosis , Chk
	Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.		Apoptosis , Chk
T1667	Tandutinib	MLN518,CT53518,NSC726292	Apoptosis , FLT , CSF-1R , PDGFR , Src , c-Kit
	Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versu...		Apoptosis , FLT , CSF-1R , PDGFR , Src , c-Kit
T0373	Erlotinib	OSI-744,NSC 718781,CP358774,R1415	EGFR , Autophagy
	Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.		EGFR , Autophagy
T2610	BMS-599626	AC480	EGFR , MEK , HER , Src
	BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.		EGFR , MEK , HER , Src
T4324	PQ401 hydrochloride (196868-63-0(free base))		IGF-1R
	PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.		IGF-1R
T62285	Enbezotinib		c-RET
	Enbezotinib is an inhibitor of RET autophosphorylation and can be used in cancer research.		c-RET
T3654	APY29		IRE1
	APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.		IRE1
T3545	RG13022	RG 13022,Tyrphostin RG13022	EGFR
	RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).		EGFR
T9650	AZ12672857		Src , Ephrin Receptor
	AZ12672857 is an inhibitor of EphB4 with IC50 of 1.3 nM. AZ12672857 inhibits cell proliferation of Src transfected 3T3 cells with IC50 of 2 nM and autophosphorylation of EphB4 in transfected CHO-K1 cells with IC50 of 9 n...		Src , Ephrin Receptor
T67779	Compound TPX-0046		c-RET
	Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound TPX-0046 can be used for the research of cancer.		c-RET
T16550	PKR-IN-C16		Others
	PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the A...		Others
T4053	AST 487	NVP-AST 487	VEGFR , FLT , c-RET , Bcr-Abl , c-Kit
	AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.		VEGFR , FLT , c-RET , Bcr-Abl , c-Kit
T3042	JAK2 Inhibitor V	JAK2 Inhibitor V Z3,Z3	JAK
	JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.		JAK
T11569	HKI-357		EGFR
	HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 (IC50s: 34 nM and 33 nM). HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.		EGFR
T7119	Y15	1,2,4,5-Benzenetetramine tetrahydrochlor,FAK Inhibitor 14	FAK
	Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) is a potent and specificsmall-molecule FAK scaffolding inhibitor that inhibits its autophosphorylation activity, blocks tumor growth.		FAK
T6619	Desmethyl Erlotinib hydrochloride	OSI420,OSI-420,DesMethyl Erlotinib (CP-473420) HCl,CP-473420,Desmethyl Erlotinib,OSI 420	EGFR , Drug Metabolite
	Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells...		EGFR , Drug Metabolite
T2693	AG1024	Tyrphostin AG 1024,Tyrphostin,AGS 200	Apoptosis , IGF-1R
	AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).		Apoptosis , IGF-1R
T3599	BFH772	BFH-722	VEGFR
	BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation ...		VEGFR
T30855	CGP77675	CGP-77675,1-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenethyl)piperidin-4-ol,ZINC1488120,CGP 77675	EGFR , VEGFR , Bcr-Abl , Src
	CGP77675 (ZINC1488120) is a potent and selective inhibitor of Src family kinase with IC50s of 5-20 and 40 nM for the phosphorylation of peptide substrates and autophosphorylation of purified Src. CGP77675 exhibits antica...		EGFR , VEGFR , Bcr-Abl , Src
T6184	Orantinib	SU6668,TSU-68,NSC 702827	Apoptosis , VEGFR , FGFR , PDGFR
	Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, A...		Apoptosis , VEGFR , FGFR , PDGFR
T23128	PD180970	PD 180970	Bcr-Abl , Src , c-Kit
	PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit. PD180970 can be used in studies about chronic myelogenous leukemia.		Bcr-Abl , Src , c-Kit
T6337	RepSox	ALK5 Inhibitor II,SJN 2511,E-616452	ALK , TGF-beta/Smad
	RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM). RepSox induces adipogenesis in MEFs cells.		ALK , TGF-beta/Smad
T3691	(Rac)-SAR131675	SAR131675	VEGFR
	(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is h...		VEGFR
T22462	1,2,3,4,5,6-Hexabromocyclohexane		Others
	The compound effectively and directly inhibits JAK2 tyrosine kinase autophosphorylation and specifically inhibits ligand-dependent JAK2 activation. It has no cytotoxicity at 100 μM. A 16-hour treatment with compound (1 μ...		Others
T69863	Dihydrogenistein
	Dihydrogenistein is a derivative of Genistein -- a compound that exhibits specific inhibitory activity against tyrosine kinases including autophosphorylation of epidermal growth factor receptor kinase.
T68360	HKI-357 dimaleate
	HKI-357 dimaleate is an irreversible dual inhibitor of EGFR and ERBB2. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.
T70568	H-1356
	H-1356 is an insulin-like growth factor 1(IGF-I) analog that inhibits autophosphorylation of IGF-I receptor.
T69260	Genistein Diglucuronide
	Genistein Diglucuronide is a metabolite of Genistein which exhibits specific inhibitory activity against tyrosine kinases including autophosphorylation of epidermal growth factor receptor kinase.
T39572	DDR1-IN-4	DDR1-IN-4
	DDR1-IN-4 (Compound 2.45) is a highly potent inhibitor that selectively targets Discoidin Domain Receptor 1 (DDR1) autophosphorylation. This compound demonstrates exceptional efficacy with IC50 values of 29 nM and 1.9 μM...

Compounds

pp60 (v-SRC) Autophosphorylation Site, Phosphorylated

T39185

Synonym: pp60 (v-SRC) Autophosphorylation Site, Phosphorylated

Target: CaMK, P2X Receptor, Autophagy

Synonym: CP724714,CP 724714

Target: Apoptosis, EGFR

ATH686

T7673

Synonym: ATH 686

Target: Apoptosis, FLT

PQ401

T2085

Synonym: IGF-1R Inhibitor II

Target: Apoptosis, IGF-1R

EGFR-IN-12

T5168

Synonym: EGFR Inhibitor

Target: Apoptosis, EGFR

Synonym: TCS PIM-1 4a,SMI-4a

Target: TGF-beta/Smad

PD-089828

T8976

Synonym:

Target: EGFR, FGFR, PDGFR, Src

Prexasertib dihydrochloride

T4327

Synonym: LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368

Target: Apoptosis, Chk, S6 Kinase

PD-161570

T23127

Synonym: PD 161570

Target: EGFR, FGFR, PDGFR, Src

AG-494

T4205

Synonym: Tyrphostin AG-494,AG 494,Tyrphostin B48

Target: Apoptosis, Chk

Tandutinib

T1667

Synonym: MLN518,CT53518,NSC726292

Target: Apoptosis, FLT, CSF-1R, PDGFR, Src, c-Kit

Erlotinib

T0373

Synonym: OSI-744,NSC 718781,CP358774,R1415

Target: EGFR, Autophagy

BMS-599626

T2610

Synonym: AC480

Target: EGFR, MEK, HER, Src

PQ401 hydrochloride (196868-63-0(free base))

Synonym: RG 13022,Tyrphostin RG13022

Target: Src, Ephrin Receptor

Target: VEGFR, FLT, c-RET, Bcr-Abl, c-Kit

JAK2 Inhibitor V

T3042

Synonym: JAK2 Inhibitor V Z3,Z3

Synonym: 1,2,4,5-Benzenetetramine tetrahydrochlor,FAK Inhibitor 14

Target: FAK

Desmethyl Erlotinib hydrochloride

T6619

Synonym: OSI420,OSI-420,DesMethyl Erlotinib (CP-473420) HCl,CP-473420,Desmethyl Erlotinib,OSI 420

Target: EGFR, Drug Metabolite

AG1024

T2693

Synonym: Tyrphostin AG 1024,Tyrphostin,AGS 200

Target: Apoptosis, IGF-1R

Synonym: CGP-77675,1-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenethyl)piperidin-4-ol,ZINC1488120,CGP 77675

Target: EGFR, VEGFR, Bcr-Abl, Src

Orantinib

T6184

Synonym: SU6668,TSU-68,NSC 702827

Target: Apoptosis, VEGFR, FGFR, PDGFR

PD180970

T23128

Synonym: PD 180970

Target: Bcr-Abl, Src, c-Kit

RepSox

T6337

Synonym: ALK5 Inhibitor II,SJN 2511,E-616452

Target: ALK, TGF-beta/Smad

1,2,3,4,5,6-Hexabromocyclohexane

Genistein Diglucuronide

Cat No.	Product Name	Synonyms	Targets
TN1549	Damnacanthal		IL Receptor , Akt , Syk
	Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its inhibitory effects on the HGF/c-Met axis.		IL Receptor , Akt , Syk

Natural Products

Damnacanthal

TN1549

Synonym:

Target: IL Receptor, Akt, Syk

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02676	EGFR Protein, Mouse, Recombinant (His)	Mouse	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-04818	EGFR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-00742	EGFR Protein, Human, Recombinant (His)	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-04529	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-00882	Mer Protein, Human, Recombinant (His & hFc)	Human	HEK293
	Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04330	Mer Protein, Human, Recombinant	Human	HEK293
	Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04051	C-Kit Protein, Human, Recombinant (hFc)	Human	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-01935	C-Kit Protein, Human, Recombinant (His)	Human	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-01802	C-Kit Protein, Mouse, Recombinant (His)	Mouse	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-05655	C-Kit Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-01037	CSF1R Protein (Met1-Glu512), Human, Recombinant (His)	Human	HEK293
	M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPK-00774	TrkA Protein, Human, Recombinant (aa 33-417, His)	Human	HEK293
	TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signa...
TMPH-01051	CILP Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligan...
TMPH-00713	Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Can form linear polymers of orthophosphate with chain lengths up to 1000 or more. Can use GTP instead of ATP,...
TMPH-02247	TRIM5 Protein, Human, Recombinant (B2M & His)	Human	E. coli
	Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting a...
TMPY-00128	EGFR Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05258	EGFR Protein, Human, Recombinant (Isoform Viii, hFc)	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-01043	EGFR Protein, Human, Recombinant (hFc)	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06593	EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06549	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-04406	Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is ...
TMPJ-00290	GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His)	Human	Human Cells
	GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two s...
TMPY-03724	EGFR Protein, Canine, Recombinant (His)	Canine	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-02675	EGFR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06524	EGFR Protein, Feline, Recombinant (His)	Feline	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05612	EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05637	EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPK-00393	FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differen...
TMPY-05211	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-02958	EGFR Protein, Rat, Recombinant (His)	Rat	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-03456	SRFBP1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	SRFBP1 contains 7 WD repeats and belongs to the WD repeat STRAP family. SRFBP1 may play a role in the cellular distribution of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in th...
TMPH-02194	TAB2 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Adapter required to activate the JNK and NF-kappa-B signaling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF). Acts as an adapter linking MAP3K7/TAK1...
TMPK-00395	FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differen...
TMPJ-00449	AXL Protein, Human, Recombinant (hFc)	Human	Human Cells
	Axl, also known as Ufo and Ark, is a widely expressed 140 kDa glycoprotein in the TAM receptor tyrosine kinase family. Axl binds the vitamin K-dependent protein Gas6 which triggers tyrosine autophosphorylation of the Axl...
TMPY-04403	NLK/Nemo Like Kinase Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Nemo-like kinase contains 1 protein kinase domain and belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. It also contains a TQE activation loop motif in which autopho...
TMPY-04412	Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Mitogen-activated protein kinase kinase kinase kinase 2, also known as B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, Rab8-interacting protein,...
TMPH-02815	Nucleophosmin Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome ...
TMPJ-00399	AXL Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Axl, also known as Ufo and Ark, is a widely expressed 140 kDa glycoprotein in the TAM receptor tyrosine kinase family. Axl binds the vitamin K-dependent protein Gas6 which triggers tyrosine autophosphorylation of the Axl...
TMPY-02291	Mer Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04440	Brk Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	Tyrosine kinase (PTKs) is a protein that carries out tyrosine phosphorylation, which play a fundamental role in cell proliferation, survival, adhesion, and motility and have also been demonstrated to mediate malignant ce...
TMPY-04437	Mer Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-03625	DDR2 Protein, Human, Recombinant (His)	Human	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-03098	DDR2 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-01728	DDR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-03166	DDR2 Protein, Rat, Recombinant (His)	Rat	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-04361	DDR2 Protein, Human, Recombinant (aa 422-855, His & GST)	Human	Baculovirus-Insect Cells
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-03593	DDR2 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-00773	DDR2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-03642	DDR2 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-04555	GRK5 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	G protein-coupled receptor kinase 5, also known as G protein-coupled receptor kinase GRK5 and GRK5, is a member of the protein kinase superfamily, AGC Ser/Thr protein kinase family, and GPRK subfamily. GRKs specifically ...
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