drosophila — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22026	AGK7		Others , Sirtuin
	AGK7 is an inactive control of AGK2, a selective SIRT2 inhibitor that selectively inhibits SIRT3 over SIRT1 and SIRT2 (IC50 = >5 μM, >50 μM and >50 μM for SIRT3, SIRT1, and SIRT2, respectively).		Others , Sirtuin
T6111	Selisistat	EX-527,SEN0014196	Sirtuin
	Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM). Selisistat can be used in the study of neurological disorders such as Huntington's chorea.		Sirtuin
T68110	Moxnidazole
	Moxnidazole, a 5-nitroimidazole, is mutagenic in microbial assays and in Drosophila, inducing genetic alterations in mouse somatic cells.
T4136	Lapachol	Bethabarra wood,CI75490,Greenhartin,Tecomin	Others , Influenza Virus , Antibacterial , Parasite , Antifungal
	Lapachol (CI75490) has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is an inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.
TP1318	Antennapedia Peptide TFA(188842-14-0 free base)	Antennapedia Peptide(TFA)	Others
	Antennapedia Peptide TFA (188842-14-0 free base), a peptide of 16 amino acids, is a member of the family of Cell-penetrating peptides, originally derived from the 60 amino acid long homeodomain of the Drosophila transcri...		Others
T15775	Lotilaner		GABA Receptor , Parasite
	Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.		GABA Receptor , Parasite
TN1078	Seneciphylline		P450 , GST
	Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutat...		P450 , GST
T60127	Chlorantraniliprole	Rynaxypyr,Chlorantranilipole,Rynaxpyr	Others
	Chlorantraniliprole (Rynaxypyr) is an insecticide. Chlorantraniliprole potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine re...		Others
T26684	Auten-99 HBr	Auten-99,Auten-99 hydrochloride. Auten-99 HBr,Auten99,Auten 99	Phosphatase
	Auten-99 HBr (Auten-99) is a myotubularin phosphatase Jumpy inhibitor exerting potent neuroprotective effects. AUTEN-99 activates autophagy in cell cultures and animal models. AUTEN-99 appears to effectively penetrate th...		Phosphatase
T28064	ML207	ML 207,LLI01-022,ML-207
	ML207 inhibits lipid storage in Drosophila melanogaster.
T25862	Neomyosuppressin	Thr-asp-val-asp-his-val-phe-leu-arg-phenh2,Dromyosuppressin,Neb-MS
	Neomyosuppressin is a myoinhibiting neuropeptide isolated from the grey fleshfly, Neobellieria bullata and Drosophila.
T40644	DL-Leucyl-DL-phenylalanine
	DL-Leucyl-DL-phenylalanine, a dipeptide, serves as a substrate for detecting two distinct regions of dipeptidase staining on gels in both Drosophila simulans and Drosophila melanogaster.
T41087	Penetratin
	Penetratin is a peptide derived from the amphiphilic Drosophila Antennapedia homeodomain.
T6664	SecinH3		Apoptosis
	SecinH3 is selective cytohesin inhibitor.		Apoptosis
T24175	Xanthumin
	Xanthumin is a naturally occurring insect development inhibitor against Drosophila melanogaster. Xanthumin is also an antibacterial compound.
T80399	Andropin
	Andropin, a male-specific antibacterial peptide, is present in Drosophila melanogaster [1].
T36801	Binucleine 2
	Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-d...
T37922	7(Z),11(Z)-Pentacosadiene
	Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones. In mature Drosophila melanogaster, certain cuticular hydrocarbons are sexually dimorphic: males synthesize 23- and 25-C...
T37923	7(Z)-Pentacosene
	7(Z)-Pentacosene is an unsaturated cuticular hydrocarbon that acts as a contact sex pheromone in fruit flies. In different species and genotypes of Drosophila, it can be found on both males and females. Pentacosene may s...
T36828	9(Z)-Tricosene
	(9Z)-Tricosene is a pheromone released by insects, including D. melanogaster, M. domestica (house fly), and A. mellifera L. (honey bee). In Drosophila, it induces aggregation behavior and is an oviposition guidance cue f...