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Search Results for " crf "

20

Compounds

Cat No. Product Name Synonyms Targets
TP2048L α-helical CRF 9-41 acetate α-helical CRF 9-41 acetate(90880-23-2 Free base) CRFR
α-helical CRF 9-41 acetate is a competitive antagonist of CRF2 (KB = 100 nM) and a partial agonist of CRF1 (EC50 = 140 nM).
TP2047L CRF (6-33) acetate(120066-38-8 free base) CRFR
CRF (6-33) acetate is a corticotropin-releasing factor binding protein (CRFBP) inhibitor peptid. CRF displaces CRF from CRFBP.
TP2047 CRF(6-33)(human) CRF (6-33)
CRF(6-33)(human) is a corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide. CRF displaces CRF from CRFBP.
TP2048 α-Helical CRF(9-41) α-helical CRF 9-41
Corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively).
TP1191 CRF, bovine Corticotropin Releasing Factor bovine
CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.
TP1190 CRF, bovine TFA (92307-52-3 free base) CRF, bovine TFA,Corticotropin Releasing Factor bovine TFA
CRF, bovine (TFA) is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM[1]. CR...
T75972 CRF, bovine TFA
CRF, bovine (TFA), acts as a potent agonist for the CRF receptor and effectively displaces [125I-Tyr]ovine CRF, demonstrating a K_i of 3.52 nM [1].
T83665 α-Helical CRF (9-41) TFA α-Helical Corticotropin-Releasing Factor (9-41)
α-Helical CRF (9-41) is a synthetic peptide antagonist that targets corticotropin-releasing factor (CRF), effectively inhibiting CRF-induced adrenocorticotropic hormone (ACTH) release both in vitro, with isolated rat ant...
T75893 CRF(6-33)(human) TFA
CRF(6-33)(human) TFA acts as a competitive inhibitor of the Corticotropin-Releasing Factor Binding Protein (CRF-BP), selectively interacting with CRF-BP without affecting post-synaptic Corticotropin-Releasing Factor rece...
T75891 α-Helical CRF(9-41) TFA
α-Helical CRF(9-41) TFA acts as a competitive antagonist for the CRF2 receptor, possessing a binding constant (K B) of approximately 100 nM. Additionally, it serves as a partial agonist for the CRF1 receptor, exhibiting ...
TP1144 Corticotropin-releasing factor (human) Human corticotropin-releasing factor,Human CRF,Corticotropin-releasing factor human
Corticotropin-releasing factor human (Human CRF; Human corticotropin-releasing factor) is an immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous syst...
T76602 (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a corticotropin-releasing factor (CRF) antagonist known to counteract the inhibitory effects of IL-1a on Luteinizing hormone (LH) production [1].
T12276 NVS-CRF38 Others
NVS-CRF38 is an antagonist of corticotropin-releasing factor receptor 1 (CRF1).
T8150 Nudifloramide 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide PARP , Endogenous Metabolite
Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).
T79793 CRF1 receptor antagonist-1 CFTR
CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to congenital adrenal hyperplasia (CAH) [1].
T69871 ICRF-196
ICRF-196 is a Topoisomerase II Inhibitor and antineoplastic agent.
T71177 LCRF-0004
LCRF-0004 is a potent and selective RON receptor tyrosine kinase inhibitor. The RON receptor tyrosine kinase has been identified as an important mediator of KRAS oncogene addiction and is overexpressed in the majority o...
T69870 ICRF-193
ICRF-193 is a DNA topoisomerase II inhibitor.
T25893 NU/ICRF 500
NU/ICRF 500 is a novel anthracenyl-amino acid catalytic inhibitor of topoisomerase II.
T60126 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine Others , CRFR
4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagoni...
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