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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3502 | C29 | TLR | |
C29 is a novel inhibitor of TLR2/1 and TLR2/6 signaling induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages. | |||
T11539 | HCV-IN-29 | HCV Protease | |
HCV-IN-29 is a hepatitis C virus (HCV) inhibitor. | |||
T18622 | BnOH-NH-bis-(C2-S)-propane-O-isoprene ester | PROTAC Linker 29 | Others |
BnOH-NH-bis-(C2-S)-propane-O-isoprene ester (PROTAC Linker 29) is an alkyl ether-based linker primarily utilized in the synthesis of PROTACs. | |||
T6351 | MGCD-265 analog | MGCD-265,Glesatinib | Apoptosis , VEGFR , c-Met/HGFR |
MGCD-265 analog (Glesatinib) is an orally bioavailable multitargeted tyrosine kinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively. | |||
T17206 | UPGL00004 | Others , Glutaminase | |
UPGL00004 is a potent glutaminase C (GAC) inhibitor with an IC50 of 29 nM. Kd of UPGL00004 for GAC was 27 nM. UPGL00004 has a strong inhibitory effect on the proliferation of highly aggressive triple negative breast canc... | |||
T6318 | AZ 628 | Apoptosis , Raf | |
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc. | |||
T4426 | CEP-40783 | CEP 40783,RXDX-106 | c-Met/HGFR , TAM Receptor |
CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM). | |||
T63590 | c-Met-IN-10 | ||
c-Met-IN-10 is a potent c-Met kinase inhibitor (IC50: 16 nM). c-Met-IN-10 inhibits the activity of cancer cells A549, H460 and HT-29, and inhibits A549 cell movement by inhibiting HT-29 cell colony formation, which in tu... | |||
T11540 | HCV-IN-3 | Others | |
HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor (IC50: 20 μM; Kd: 29 μM). | |||
T125696 | Scheffursoside C | ||
Scheffursoside C is a useful organic compound for research related to life sciences. The catalog number is T125696 and the CAS number is 160669-29-4. | |||
TP1231 | β-Amyloid (29-40) | Amyloid beta-protein(29-40),β-Amyloid 29-40 | |
β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties related to those of fusion peptides of viral proteins. The fusio... | |||
T79715 | c-Met-IN-19 | c-Met/HGFR | |
c-Met-IN-19 (Compound 21j) is a potent c-Met inhibitor with an IC50 of 1.99 nM and demonstrates cytotoxic effects on various cancer cell lines, including A549, HT-29, SGC-7901, and MDA-MB-231, with IC50 values of 0.25, 0... | |||
TN1993 | Norsanguinarine | Antifection | |
Norsanguinarine has antifungal activity, it exhibits 100 % inhibition of A. brassicicola and C. maculans at 1000 ppm whereas. It shows significant cytotoxic activities (ED (50) values < 4 microg/ml) against P-388, KB16, ... | |||
T36913 | 17-Epiestriol | ||
17-Epiestriol is a metabolite of estrone .1It is formed from estroneviaa 16α-hydroxy estrone intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding af... | |||
T83738 | SMAP 29 (ovine) TFA | Sheep Myeloid Antimicrobial Peptide 29 | |
SMAP 29, a bactericidal antimicrobial peptide and a cleavage product from the C-terminus of an ovine cathelicidin prepropeptide, is effective against P. aeruginosa strain PAO1 in both low- and high-salt conditions, as de... | |||
T37922 | 7(Z),11(Z)-Pentacosadiene | ||
Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones. In mature Drosophila melanogaster, certain cuticular hydrocarbons are sexually dimorphic: males synthesize 23- and 25-C... | |||
TN3870 | Iriflophenone 2-O-Rhamnoside | Dimethylmatairesinol | Others |
Dimethylmatairesinol can reduce the amount of Immunoglobulin E (IgE) secreted by human myeloma U266 cells, it has potential as an anti-allergic agent. Dimethylmatairesinol also exhibits significant cytotoxicity against t... | |||
T36929 | Pal-KTTKS (acetate) | ||
Pal-KTTKS is a lipidated pentapeptide consisting of a fragment of the type I collagen C-terminal propeptide conjugated to palmitic acid .1 It increases collagen production in human corneal and dermal fibroblasts when use... | |||
T36431 | 7,10-dihydroxy-8(E)-Octadecenoic Acid | ||
7,10-dihydroxy-8(E)-Octadecenoic acid is a hydroxy fatty acid and metabolite of oleic acid that is produced byP. aeruginosafrom vegetable oils.1It is active against the food-borne pathogenic bacteriaS. aureus,S. typhimur... | |||
T36991 | Monascuspiloin | ||
Monascuspiloin is a fungal metabolite that has been found inM. pilosusM93-fermented rice.1It induces endoplasmic reticulum stress and autophagy in PC3 prostate cancer cells. Monascuspiloin (15-45 μM) decreases viability ... |