ox receptor

Orexin B, rat, mouse Acetate (Rat orexin B) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.

[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).

Orexin A (human, rat, mouse) acetate (Hypocretin-1) is an excitatory neuropeptide with analgesic properties. It activates Orexin-1 (OX1R) and Orexin-2 (OX2R) receptors, used for studying neurodegenerative diseases.

OXA (17-33) acetate is a more potent agonist of orexin-1 receptor (OX1, EC50 = 8.29 nM)) over OX2 (EC50 = 187 nM).

Orexin B, human acetate is the acetate form of Orexin B, human. It acts as an agonist for the orexin receptors (Orexin Receptor, OX Receptor), with a Ki of 420 nM for OXR1 and 36 nM for OXR2. Orexin B, human acetate plays a role in modulating appetite, wakefulness, cardiovascular function, and neuroendocrine activity.