ide-2

inducer of definitive endoderm formation

Autocamtide-2-related inhibitory peptide, myristoylated acetate is a CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide.

Autocamtide-2-related inhibitory peptide is a potent and highly specific inhibitor of CaMKII, with an IC50 of 40 nM.

Tetrapeptide-21 Acetate is a novel bioactive and pure tetrapeptide with anti-aging properties based on the skin's own structures for use in skincare formulations.

Tripeptide-29 Acetate is a research chemical this increases the condition of skin and helps reduce fine lines and wrinkles.

Octapeptide-2 Acetate, as a hair growth promotion active, is a double-layered encapsulated biomimetic peptide that helps increase cell growth and migration. It promotes hair growth by activating the stem cells of the hair follicles. Octapeptide-2 is more stable and prolongs action than native proteins.

(S)-Deoxy-thalidomide-2,7-diazaspiro[3.5]nonane-C-Pip is a conjugate of an E3 ubiquitin ligase ligand and a linker, employed in the synthesis of PROTACFHD-609.

WWamide-2 is used as a neuromodulatory peptide isolated from the ganglia of African giant snail, Achatina fulica.

Competence-Stimulating Peptide-2 (CSP-2) is a quorum sensing signal peptide synthesized by Streptococcus pneumoniae. Its compatible receptor, ComD2, exhibits an EC50 value of 50.7 nM.

Phospho-Glycogen Synthase Peptide-2, a substrate for glycogen synthase kinase-3 (GSK-3), serves as a peptide substrate effective in the affinity purification of protein-serine kinases.

Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent CaMKII inhibitor with an IC50 value of 40 nM.

Myristoylated Autocamtide-2-related inhibitory peptide, trifluoroacetic acid (TFA) form, is a potent and highly specific inhibitor of CaMKII, exhibiting an IC50 of 40 nM [1]. This compound constitutes the myristoylated variant of Autocamtide-2-related inhibitory peptide.

Phospho-Glycogen Synthase Peptide-2 (substrate) serves as a peptide substrate for glycogen synthase kinase-3 (GSK-3) and is used for the affinity purification of protein-serine kinases [1].

AKTide-2T TFA, serving as an optimal in vitro substrate for AKT, demonstrates competitive inhibition of histone H2B phosphorylation with a Ki value of 12 nM. It effectively mimics the optimal phosphorylation sequence of Akt and acts as an inhibitory peptide, distinct from the wildtype AKTide due to the absence of Thr at the S22 position [1].

Myelopeptide-2, a peptide isolated from the supernatant of porcine bone marrow cell cultures, can restore the mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. It also enhances depressed interleukin-2 (IL-2) synthesis and interleukin-2 receptor (IL-2R) expression, playing a role in immunity homeostasis. This compound shows potential for application in antitumor and antivirus research [1] [2].

Octapeptide-2, a bioactive peptide, is recognized for its hair growth-promoting properties and is commonly used as a cosmetic ingredient [1].

Oligopeptide-20, a bioactive peptide, is renowned for its skin repair properties and is commonly utilized as a cosmetic ingredient [1].

Trifluoroacetyl tripeptide-2, a bioactive peptide recognized for its anti-aging properties, is utilized as a cosmetic ingredient [1].

Tetrapeptide-26, a bioactive peptide, is known for its anti-aging properties and is reportedly utilized as an ingredient in cosmetics [1].

Tetrapeptide-21, a bioactive peptide with anti-wrinkle and skin hyperpigmentation-reducing effects, is commonly used as a cosmetic ingredient [1].

Palmitoyl Tetrapeptide-20 (PTP20) is a bioactive peptide known to preserve the function of follicular melanocytes and is reported to be used as an ingredient in cosmetics [1].

Oligopeptide-24 (CG-EDP3) is a bioactive peptide recognized for its skin repair properties, frequently utilized as an ingredient in cosmetics [1].

Acetyl Tetrapeptide-22 is a bioactive peptide known for its skin repair effects and is commonly utilized as a cosmetic ingredient [1].

IDE-IN-3 (Compound 4) serves as an inhibitor of Insulin-Degrading Enzyme (IDE). Computational predictions suggest that IDE-IN-3 potentially inhibits CYP3A4, CYP2C19, hERG, NADP+, HIF1α, and histidine kinase. This compound may exhibit biological activities in anti-diabetic, anti-tumor, and antibacterial applications.