exceptional — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14933	Cetaben		Others
	Cetaben is a PPARα-independent peroxisome proliferator and is a non-fibrate hypolipidemic drug. It potent reduces the concentration of cholesterol and triglycerides.		Others
T13312L	Seviteronel	VT-464	Others
	Seviteronel is an effective CYP17 lyase inhibitor (h-Lyase IC50=69 nM). In a hamster model of androgen biosynthesis inhibition, it demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral...		Others
T35862	Cucurbit[8]uril		Others
	Cucurbit[8]uril is a highly effective and safe supramolecular compound that promotes protein heterodimerization. It selectively induces the heterodimerization of methylviologen and naphthalene functionalized proteins, de...		Others
T22322	EEDi-5285	UM-EEDi-5285,EEDI5285	Histone Methyltransferase
	EEDi-5285, an orally active and highly potent inhibitor targeting embryonic ectoderm development (EED) protein, exhibits anti-cancer activity. It demonstrates exceptional efficacy with an IC50 value of 0.2 nM, indicating...		Histone Methyltransferase
T16115	MLi-2		LRRK2
	MLi-2 is a structurally novel, highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a ce...		LRRK2
T22341	GSK-114		Others
	GSK-114, a selective inhibitor of TNNI3 Interacting Kinase (TNNI3K) with IC50 of 25 nM, shows significant bias for TNNI3K over B-Raf with IC50 of 1000 nM, exceptional broad spectrum kinase selectivity and adequate oral e...		Others
T28641	S-14671
	S-14671 is a 5-HT1A receptor agonist (pKi = 9.3) with high efficacy and exceptional in vivo potency. S-14671 also acts as a 5-HT2A and 5-HT2C receptor antagonist (both are pKi = 7.8).
T40077	ATR-IN-9
	ATR-IN-9 is a highly effective inhibitor of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). With an IC50 value as low as 10 nM, ATR-IN-9 demonstrates exceptional potency.
T33765	NVX-108	Dodecafluoropentane,DDFP,Perfluoropentane
	NVX-108 is an exceptional oxygen transporter which increases brain tissue oxygen tension (PbtO2) when administered soon after traumatic brain injury (TBI).
T39572	DDR1-IN-4	DDR1-IN-4
	DDR1-IN-4 (Compound 2.45) is a highly potent inhibitor that selectively targets Discoidin Domain Receptor 1 (DDR1) autophosphorylation. This compound demonstrates exceptional efficacy with IC50 values of 29 nM and 1.9 μM...
T74966	Antimicrobial agent-10
	Antimicrobial Agent-10 demonstrates exceptional antibacterial activity and inhibits SARS-CoV-2, positioning it as a potent antimicrobial compound [1].
T40196	PI3Kγ inhibitor 5
	PI3Kγ inhibitor 5 is a potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ), exhibiting an exceptional IC50 value of 34 nM.
T40275	DHPS-IN-1
	DHPS-IN-1, a chemical compound, demonstrates exceptional inhibitory potency against melanoma cells, as evidenced by its IC50 value of 0.014 μM.
T38435	RB-OPD	RB-OPD,NO-red
	RB-OPD, also known as NO-red, is a fluorescent probe that combines o-phenylenediamine (OPD) and rhodamine nitric oxide (NO). With a λex of 550 nm and a λem of 590 nm, it exhibits exceptional sensitivity and selectivity.
T61076	Vildagliptin dihydrate
	Vildagliptin dihydrate (LAF237 dihydrate) is a powerful and stable dipeptidyl peptidase IV (DPP-IV) inhibitor, demonstrating selectivity with an IC50 of 3.5 nM in human Caco-2 cells. This compound exhibits exceptional or...
T39825	(Rac)-Salvianic acid A	(Rac)-Danshensu
	(Rac)-Salvianic acid A, also known as (Rac)-Danshensu, is a phenolic acid compound that possesses exceptional radical scavenging and antioxidant properties.
T35661	QTX125
	QTX125, a powerful and highly specific HDAC6 inhibitor, demonstrates exceptional selectivity in comparison to other HDACs, resulting in robust antitumor activity[1].
T40329	Antifungal agent 14
	Antifungal agent 14 demonstrates potent broad-spectrum antifungal activity, effectively targeting a variety of fungal strains with exceptional minimum inhibitory concentration values.
T38780	GSK2332255B
	GSK2332255B is a highly potent and selective TRPC3 and TRPC6 antagonist, exhibiting IC50 values of 5 nM and 4 nM for rat TRPC3 and rat TRPC6, respectively. Furthermore, GSK2332255B demonstrates exceptional selectivity, s...
T39432	HKOCl-4	HKOCl-4,BXY2142
	HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe that demonstrates exceptional sensitivity and selectivity in detecting hypochlorous acid. Its absorption wavelength is significantly longer than that of fluore...