mri — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T39410	Zevaquenabant	(S)-MRI-1867
	Zevaquenabant ((S)-MRI-1867), a dual cannabinoid CB1 receptor and inducible NOS (iNOS) antagonist, is orally bioavailable and peripherally restricted. It effectively mitigates obesity-induced chronic kidney disease (CKD)...
T79137	Monlunabant	(S)-MRI-1891	Cannabinoid Receptor
	Monlunabant ((S)-MRI-1891), a solid dispersion compound, functions as an inhibitor of the cannabinoid CB1 receptor [1].		Cannabinoid Receptor
T83533	(R)-Monlunabant	(R)-MRI-1891	Cannabinoid Receptor
	(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research [1].		Cannabinoid Receptor
T39074	(Rac)-Zevaquenabant	(Rac)-MRI-1867,(Rac)-Zevaquenabant
	(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of the cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), exhibiting a binding affinity (Ki) of 5.7 nM sp...
T8406	Gadobutrol	ZK 135079	Others
	Gadobutrol is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI)		Others
T19333	Gadoteridol	ProHance,SQ-32692,Gd-HP-DO3A	Others
	Gadoteridol (Gd-HP-DO3A) is a gadolinium-based MRI contrast agent that can be used for central nervous system imaging.		Others
T1265	Amrinone	Inamrinone,Inocor,Wincoram	TNF , PDE
	Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory activity.		TNF , PDE
T26623	AMRI-59	AMRI 59	Others
	AMRI-59 is a potent inhibitor of PrxI with anti-tumor activity.		Others
T60202	MMRi62	7-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol	Ferroptosis
	MMRi62 (7-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol), a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity aga...		Ferroptosis
T28078	MMRi64		Apoptosis , Mdm2 , p53
	MMRi64 is a specific inhibitor of Mdm2-MdmX E3 ligase activity.MMRi64 potently induces p53 accumulation and apoptosis in the p53 pathway in leukemia/lymphoma cells, disrupts Mdm2-MdmX interactions, and downregulates Mdm2...		Apoptosis , Mdm2 , p53
T6826	Emricasan	PF 03491390,IDN-6556	Influenza Virus , Caspase
	Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties. Emricasan has anti-inflammatory and anti-apoptotic activity and can be used in the treatment of infections and liver failure, etc. Emricasan a...		Influenza Virus , Caspase
T36891	MRIA9
	MRIA9, an ATP-competitive inhibitor targeting pan Salt-Inducible Kinases (SIK) and PAK2/3, demonstrates IC50 values of 516 nM, 180 nM, and 127 nM for SIK1, SIK2, and SIK3, respectively [1].
T80471	α-Conotoxin MrIC
	α-Conotoxin MrIC is a biased agonist selective for the α7 nicotinic acetylcholine receptor (nAChR), with activation contingent upon the presence of type II positive allosteric modulators, such as PNU120596. It is utilize...
T81155	Simridarlimab
	Simlukafusp alfa (Simridarlimab) is a humanized immunoglobulin antibody that targets the CD274/PD-L1 and CD47 pathways.[1]
T68742	Inamrinone lactate
	Inamrinone lactate is a positive inotropic cardiotonic with vasodilator properties, phosphodiesterase inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
T4506	Gadopentetate dimeglumine	Meglumine gadopentetate,SH-L-451A,Gd-DTPA,Gadopentetic acid dimeglumine,Gadopentetic acid dimeglumine salt	Others
	Gadopentetate dimeglumine (Gd-DTPA), an extracellular intravenous contrast agent, is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more cl...		Others
T5161	Gadodiamide		Others
	Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.		Others
T19332	Gadopentetic acid	gadolinium complex,Gd-DTPA	Others
	Gadopentetic acid (gadolinium complex) (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies.		Others
T67967	EOB-DTPA	N-((2s)-2-(bis(carboxymethyl)amino)-3-(4-ethoxyphenyl)propyl)-n-(2-(bis(carboxymethyl)amino)ethyl)glycine	Others
	EOB-DTPA is a biochemical reagent that can be synthesized from other compounds and is commonly used in MRI.		Others
T15367	Gadoxetate Disodium	Gd-EOB-DTPA Disodium,ZK 139834	Others
	Gadoxetate Disodium is used to evaluate focal liver lesions, such as hepatocellular carcinoma or liver metastasis on T1-weighted imaging. It is a contrast agent in magnetic resonance imaging (MRI) of the hepatobiliary sy...		Others