TP2327L |
Y16 acetate(429653-73-6 free base)
|
TP2327L
|
|
|
Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA act...
|
TP2130L |
Rac1 Inhibitor F56, control peptide acetate
|
TP2130L
|
98%
|
|
Rac1 Inhibitor F56, control peptide acetate is a control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not...
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T12452 |
Digeranyl bisphosphonate
|
878143-03-4
|
98%
|
|
Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.Digeranyl bi...
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T16746 |
Rhosin
|
1173671-63-0
|
98%
|
|
Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin...
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T2014 |
CCG-1423
|
285986-88-1
|
99.98%
|
|
CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.
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T30778 |
CCG-257081
|
1922098-90-5
|
99.92%
|
|
CCG-257081 (MRTF/SRF-IN-1) is an inhibitor of cardiac myosin-related transcription factor and serum response factor (MRTF/SRF) that acts by inhibiting the Rho/MR...
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T22062 |
CCG-100602
|
1207113-88-9
|
99.86%
|
|
CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).
|
T22991 |
ML-099
|
496775-95-2
|
99.48%
|
|
pan activator of Ras-related GTPases
|
T6342 |
NSC 23766 trihydrochloride
|
1177865-17-6
|
99.35%
|
|
NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 μM); no inhibitory for the closely related ...
|
T25450 |
GGTI 2147
|
191102-87-1
|
99.32%
|
|
GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.
|
T15602 |
ITX3
|
347323-96-0
|
99.02%
|
|
ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM. ITX3 has anticancer effects, inhibits trion mediated GTP exchange ...
|
TP2131L |
Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
|
TP2131L
|
98.96%
|
|
Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with...
|
T16745 |
Rhosin hydrochloride
|
1281870-42-5
|
98.92%
|
|
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0...
|
T7764 |
CCG-222740
|
1922098-69-8
|
98.79%
|
|
CCG-222740 is an inhibitor of Rho/MRTF pathway
|
T61448 |
AZA1
|
1071098-42-4
|
98.59%
|
|
AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induced apoptosis of prostate cancer cells and inhibited cell proliferation, migration ...
|
T26193 |
SKLB-163
|
1255099-06-9
|
98.31%
|
|
SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.
|
T3553 |
Y16
|
429653-73-6
|
98.26%
|
|
Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated sign...
|
T8473 |
MLS000532223
|
16616-39-0
|
98.11%
|
|
MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).
|
T24642 |
YH-306
|
1373764-75-0
|
97.87%
|
|
YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
|
T2427 |
EHop-016
|
1380432-32-5
|
97.69%
|
|
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.
|