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Glucagon Receptor

The glucagon receptor is a 62 kDa protein that is activated by glucagon and is a member of the class B G-protein coupled family of receptors, coupled to G alpha i, Gs and to a lesser extent G alpha q. Stimulation of the receptor results in activation of adenylate cyclase and increased levels of intracellular cAMP. In humans, the glucagon receptor is encoded by the GCGR gene.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T40997 GLP-1R modulator C16 875005-43-9 99.6%
GLP-1R modulator C16
GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4.
T40279 GLP-1R modulator L7-028 2648317-95-5 98.76%
GLP-1R modulator L7-028
GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.
T60047 V-0219 878453-71-5 100%
V-0219
V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.
TP1148L Glucagon-like peptide 1 (1-37), human acetate 98%
Glucagon-like peptide 1 (1-37), human acetate
Glucagon-like peptide 1 (1-37), human acetate is a highly potent the GLP-1 receptor agonist.
TP1452L1 HAEGTFTSD acetate(926018-45-3 free base) 98%
HAEGTFTSD acetate(926018-45-3 free base)
HAEGTFTSD acetate is the first N-terminal 1-9 residues of GLP-1 peptide.The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from in...
T12878 Semaglutide TFA (910463-68-2 free base) 98%
Semaglutide TFA (910463-68-2 free base)
Semaglutide TFA is a agonist of glucagon-like peptide-1 (GLP-1) receptor,with a potential for type 2 diabetes treatment.
T35337 Teduglutide 197922-42-2 98%
Teduglutide
Teduglutide is a useful organic compound for research related to life sciences. The catalog number is T35337 and the CAS number is 197922-42-2.
T76279L1 Retatrutide sodium salt 99.97%
Retatrutide sodium salt
Retatrutide sodium salt is a potent triple agonist peptide for glucagon receptor (GCGR), glucose-dependent proinsulinotropic polypeptide receptor (GIPR), and glu...
T14130 Adomeglivant 1488363-78-5 99.97%
Adomeglivant
Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.
T9226 CCG-143140 891016-02-7 99.94%
CCG-143140
CCG-143140 is a GLP-1 receptor inverse agonists.
TP1469 Lixisenatide acetate (320367-13-3 free base) 1997361-87-1 99.9%
Lixisenatide acetate (320367-13-3 free base)
Lixisenatide acetate is a receptor agonist similar to glucagon-like peptide-1 (glp-1) for the treatment of type 2 diabetes mellitus (T2DM).
T3984 GLP-1(7-36), amide 107444-51-9 99.85%
GLP-1(7-36), amide
GLP-1(7-36), amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and dis...
T76559 Survodutide 2805997-46-8 99.83%
Survodutide
Survodutide (BI 456906) is a dual agonist of glucagon and glucagon-like peptide 1 (GLP-1) receptor (GLP Receptor) that reduces body weight in HbA1c16 diabetes.
T28182 NNC 92-1687 22903-37-3 99.72%
NNC 92-1687
NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.
T3967 Exendin-4 141758-74-9 99.72%
Exendin-4
Exendin-4 (Exenatide) is a glucagon-like peptide-1 receptor (GLP-1) agonist (IC50: 3.22 nM). Exenatide is a 39 amino acid peptide. Compared to GLP-1, exenatide h...
TP1111L1 Tirzepatide sodium salt 99.69%
Tirzepatide  sodium salt
Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.
T61483 GLP-1R modulator C5 421578-93-0 99.59%
GLP-1R modulator C5
GLP-1R modulator C5 is a small molecule GLP-1R orthosteric modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study o...
T63166L (S, R)-LSN 3318839 2765539-92-0 99.57%
(S, R)-LSN 3318839
(S, R)-LSN 3318839 is an allosteric modulator of the glucagon-like peptide-3318839 receptor (GLP-1R) that has demonstrated powerful hypoglycemic effects in anima...
T19850 Semaglutide 910463-68-2 99.56%
Semaglutide
Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).
T12431 PF-06882961 2230198-02-2 99.54%
PF-06882961
PF-06882961 is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.
GLP-1R modulator C16
T40997
GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4.
GLP-1R modulator L7-028
T40279
GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.
V-0219
T60047
V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.
Glucagon-like peptide 1 (1-37), human acetate
TP1148L
Glucagon-like peptide 1 (1-37), human acetate is a highly potent the GLP-1 receptor agonist.
HAEGTFTSD acetate(926018-45-3 free base)
TP1452L1
HAEGTFTSD acetate is the first N-terminal 1-9 residues of GLP-1 peptide.The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from in...
Semaglutide TFA (910463-68-2 free base)
T12878
Semaglutide TFA is a agonist of glucagon-like peptide-1 (GLP-1) receptor,with a potential for type 2 diabetes treatment.
Teduglutide
T35337
Teduglutide is a useful organic compound for research related to life sciences. The catalog number is T35337 and the CAS number is 197922-42-2.
Retatrutide sodium salt
T76279L1
Retatrutide sodium salt is a potent triple agonist peptide for glucagon receptor (GCGR), glucose-dependent proinsulinotropic polypeptide receptor (GIPR), and glu...
Adomeglivant
T14130
Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.
CCG-143140
T9226
CCG-143140 is a GLP-1 receptor inverse agonists.
Lixisenatide acetate (320367-13-3 free base)
TP1469
Lixisenatide acetate is a receptor agonist similar to glucagon-like peptide-1 (glp-1) for the treatment of type 2 diabetes mellitus (T2DM).
GLP-1(7-36), amide
T3984
GLP-1(7-36), amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and dis...
Survodutide
T76559
Survodutide (BI 456906) is a dual agonist of glucagon and glucagon-like peptide 1 (GLP-1) receptor (GLP Receptor) that reduces body weight in HbA1c16 diabetes.
NNC 92-1687
T28182
NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.
Exendin-4
T3967
Exendin-4 (Exenatide) is a glucagon-like peptide-1 receptor (GLP-1) agonist (IC50: 3.22 nM). Exenatide is a 39 amino acid peptide. Compared to GLP-1, exenatide h...
Tirzepatide sodium salt
TP1111L1
Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.
GLP-1R modulator C5
T61483
GLP-1R modulator C5 is a small molecule GLP-1R orthosteric modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study o...
(S, R)-LSN 3318839
T63166L
(S, R)-LSN 3318839 is an allosteric modulator of the glucagon-like peptide-3318839 receptor (GLP-1R) that has demonstrated powerful hypoglycemic effects in anima...
Semaglutide
T19850
Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).
PF-06882961
T12431
PF-06882961 is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.
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TargetMol