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Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.

CID21480113, an antibacterial agent, is effective in treating dapsone resistant leprosy.

5-Ph-IAA is an IAA derivative and a highly efficient, low-toxicity, reversible protein degradation ligand specifically designed for the AID2 system. AID2 induces rapid and effective depletion of mAID fusion proteins, enabling the study of protein function in living cells; it also exhibits antitumor activity. 5-Ph-IAA can be used in antitumor research.

ZD-2138 is a potent and selective specific inhibitor of 5-lipoxygenase (5-LOX) that inhibits allergen-induced pulmonary bronchoconstriction and reduces neurally-induced fast-acting kallikrein-ergic constriction of isolated airways in guinea pigs.ZD-2138 can be used for the treatment of asthma disease.

Ketoconazole (R-41400) is an imidazole antifungal agent with broad-spectrum antifungal activity that primarily acts by inhibiting the biosynthesis of ergosterol in the fungal cell membrane. Ketoconazole inhibits the fungal cytochrome P450-dependent enzyme lanosterol 14α-demethylase (CYP51), thereby blocking the conversion of lanosterol to ergosterol. This leads to damage to the cell membrane structure and permeability, consequently inhibiting fungal growth and producing an antifungal effect. In addition, ketoconazole is a non-selective cytochrome P450 (CYP) inhibitor, specifically inhibiting drug-metabolizing enzymes such as human CYP3A4. In terms of endocrinology, ketoconazole also inhibits various enzymes involved in steroid synthesis (CYP17A1, CYP11A1).

L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) functions as an antioxidant and stimulates hepatocyte growth factor (HGF) production. This long-acting vitamin C derivative promotes collagen formation and expression.

L-ascorbic acid 2-phosphate (Vitamin C phosphate) is a stable and long-lasting vitamin C derivative that stimulates collagen formation and has potential antioxidant capacity. L-ascorbic acid 2-phosphate is commonly used to promote osteogenic differentiation of human adipose stem cells (hASCs) in cell culture by increasing alkaline phosphatase (ALP) activity and runt-related transcription factor-2-DNA(runx2A) expression.

L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) is utilized in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays.

3,4-Dihydro-1H-pyrrolo[1,2-a]pyrazine-2,6-dicarboxylic acid 2-tert-butyl ester 6-methyl ester ,with CAS No. 1363383-12-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3,4-Dihydro-1H-pyrrolo[1,2-a]pyrazine-2,6-dicarboxylic acid 2-tert-butyl ester 6-methyl ester provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(5-Pyrrolidin-1-ylpyrid-2-yl)methanol ,with CAS No. 930110-98-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (5-Pyrrolidin-1-ylpyrid-2-yl)methanol provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

N-[5-(trifluoromethyl)pyrid-2-yl]-n-methylhydrazine ,with CAS No. 163620-24-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N-[5-(trifluoromethyl)pyrid-2-yl]-n-methylhydrazine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-[5-(Trifluoromethyl)pyrid-2-yl]-1,4-diazepane ,with CAS No. 306934-70-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-[5-(Trifluoromethyl)pyrid-2-yl]-1,4-diazepane provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.37 ± 0.15).

Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.

(3-FLUOROPYRID-2-YL)METHANOL, with CAS No. 31181-79-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (3-FLUOROPYRID-2-YL)METHANOL provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).

CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.

Docosapentaenoic acid 22n-3 is present in the cell membranes of all animals and is a component of phospholipids.

Lipid 23 is an ionizable cationic amino lipid used for the creation of lipid nanoparticles (LNP) and the delivery of mRNA.

Lipid 29 is an unsaturated, ionizable cationic lipid that facilitates the formation of lipid nanoparticles (LNP) used for intrabody mRNA delivery. When integrated into LNPs encapsulating luciferase reporter gene mRNA, intravenous injection of these LNPs induces bioluminescence in the lungs and spleen of mice.

Synucleozid-2.0 is an innovative compound under investigation for neurodegenerative disease research, potentially acting by modulating neurotransmitters and cellular signaling pathways.

OH-PEG3-C2-Succinamic acid-2-(Methylamino)ethanol serves as a PROTAC linker and is utilized in the synthesis of PROTAC Tamoxifen-PEG-Clozapine.

SID 24785302 is an inhibitor of hexokinase, which can suppress glycolysis, regulate mitochondrial function, and ultimately inhibit the replication of mutant mitochondrial DNA.

CID 2745687 is a moderately potent, concentration-dependent antagonist at human GPR35 with pIC50 = 6.70. CID 2745687 cannot effectively antagonize the agonist effects of either Zaprinast or Cromolyn disodium at rodent ortholog of GPR35 in vitro[1]. However, CID 2745687 can reverse lodoxamide-mediated anti-fibrotic effects in mice in vivo[2].