effector — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5210	BAI1		Apoptosis , BCL
	BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).		Apoptosis , BCL
T10826	CK-666		HIV Protease , Microtubule Associated
	CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex. It binds to the Arp2/3 complex, stabilizes the inactive state of the complex, blocking the movement of the Arp2 and Arp3 subunits into the act...		HIV Protease , Microtubule Associated
T6751	Acetylcholine iodide	Acetylcolina	Others
	Acetylcholine iodide (Acetylcolina) is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the cent...		Others
T19889	L-5-BromoTryptophan	5-BrW,5 BrW	Others
	L-5-BromoTryptophan (5-BrW) is an analog of the tryptophan (Trp) effector and inhibits the gelation of hemoglobin S.		Others
TP2506	Ser-Asn-Thr-Arg
	Ser-Asn-Thr-Arg is a tetrapeptide compound formed by truncation of a transcription activator-like effector.
T9184L	Compound 3344 hydrochloride	4-(2,3-dihydro-1,4-benzodioxin-5-yl)-~{N}-[3-[(dimethylamino)methyl]phenyl]-2-methoxy-aniline hydrochloride(2368246-78-8 free base),Compound 3344 hydrochloride (2368246-78-8 free base)	Ras
	Compound 3344 hydrochloride is an inhibitor of KRAS-effector interactions，with an affnity of 126nm.		Ras
T20344	Acetylcholine bromide		Others
	Acetylcholine bromide is the bromide salt of acetylcholine. It is an neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, a...		Others
T24706	RBC10	RBC 10,RBC-10	GTPase
	RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines.		GTPase
T6738	Z-FA-FMK		SARS-CoV , Cysteine Protease
	Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.		SARS-CoV , Cysteine Protease
T6634	RBC8		GTPase , Ras
	RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.		GTPase , Ras
T77471	Tinurilimab	BAY 1834942
	Tinurilimab (Bay 1834942) is a monoclonal antibody that targets and inhibits CEACAM6, an immune checkpoint regulator. Tinurilimab can be used in studies about effector T-cells against tumors.
T11718	JI051	JI-051	Gamma-secretase
	JI051 is an antitumor agent that interacts with the cancer-associated protein chaperone prohibitin 2 (PHB2) to induce cell cycle arrest by inhibiting the transcription of the Notch downstream effector gene, Hes1, and inh...		Gamma-secretase
TP1076L	AUNP-12 acetate	AUNP-12 acetate (1353563-85-5 Free base)	PD-1/PD-L1
	AUNP-12 acetate is a polypeptide inhibitor of PD-1 that is equivalent to PD-1 and PD-2 in inhibiting lymphocyte proliferation and effector fuction, in addition to immune activation and antitumor activity.		PD-1/PD-L1
T9901A-005	Zolbetuximab	IMAB362	Others
	Zolbetuximab(IMAB362) is a monoclonal antibody that specifically targets Claudin-18.2.Zolbetuximab has potential antitumor activity, mediating killing of Claudin-18.2-positive cells through an immune effector mechanism.Z...		Others
T77170	Siplizumab	MEDI-507	Others
	Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody targeting CD2. Siplizumab selectively depletes effector memory T cells and promotes relative expansion of alloreactive regulatory T cells in vitro. Siplizumab...		Others
T4973	Paraxanthine	1,7-DIMETHYLXANTHINE	Endogenous Metabolite
	Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is struc...		Endogenous Metabolite
T77370	Ianalumab	VAY-736	Others
	Ianalumab (VAY-736) is a decarboxylated humanized antibody against BAFF-R. Ianalumab can inhibit the interaction between BAFF and BAFF-R and inhibit the protection of apoptosis mediated by BAFF. Ianalumab has antibody de...		Others
T24707	RBC6	RBC-6,RBC 6
	RBC6 is an inhibitor of the binding of Ral to its effector RALBP1.
T19888	6BrW	6-BrW,6 BrW
	6BrW is an analog of tryptophan effector.
T32439	L 35	L-35,L35
	L 35 is kind of a negative effector of hemoglobin.