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Jervine
Jerwiny, Iervin, 11-Ketocyclopamine
T3363469-59-0
The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited, the GLI1 transcription cannot be activated and Hedgehog target genes cannot be transcribed.
  • $64
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Bovine Serum Albumin
BSA, Bovine albumin, Albumin bovine serum
T56649048-46-8
Bovine Serum Albumin (BSA) is a globular protein employed in various biochemical applications.
  • $33
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Conalbumin
Ovotransferrin
TP29041391-06-6
Conalbumin (ovotransferrin) is an egg white protein and glycoprotein with antimicrobial, antioxidant, and immunomodulatory properties as a member of the transferrin and metalloprotease families. Conalbumin has a binding logarithm of 15 for Fe3+ at pH 7 or higher.
  • $30
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Alternaphenol B2
T83133
Alternaphenol B2, a selective inhibitor of mutant isocitrate dehydrogenase 1 (IDH1m), is sourced from the coral-derived fungus Parengyodontium album SCSIO SX7W11. It exhibits inhibitory activity specifically against the IDH1 R132H mutation, with an IC50 of 41.9 μM [1].
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