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Angiotensin-converting Enzyme (ACE)

Angiotensin-converting enzyme, or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. It converts the hormone angiotensin I to the active vasoconstrictor angiotensin II. Therefore, ACE indirectly increases blood pressure by causing blood vessels to constrict. ACE inhibitors are widely used as pharmaceutical drugs for treatment of cardiovascular diseases. Other lesser known functions of ACE are degradation of bradykinin, substance P and amyloid beta-protein.

Filter Home Signaling PathwaysMetabolismAngiotensin-converting Enzyme (ACE)
  • Zabicipril HCl
    T68171L90130-77-1In house
    Zabicipril HCl(S 9650) is a potent angiotensin-converting enzyme inhibitor.
    • $195
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    TargetMol | Inhibitor Sale
  • Palatrigine
    T2458898410-36-7In house
    Palatrigine (BW-A 256C) is a compound with angiotensin-converting enzyme inhibitory and beta-adrenergic receptor blocking properties.
    • $80
    In Stock
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  • Tuna AI acetate
    T24906L
    Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.
    • $195
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    TargetMol | Inhibitor Sale
  • Libenzapril
    T27827109214-55-3In house
    Libenzapril (CGS 16617) is a potent angiotensin-converting enzyme inhibitor used to study myocardial injury.
    • $250
    In Stock
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  • H-Ile-Pro-Pro-OH acetate
    TP1750L
    H-Ile-Pro-Pro-OH acetate is a angiotensin-converting enzyme inhibitor (ACE) of milk-derived tripeptides.
    • $77
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  • Garcinone B
    T7877076996-28-6
    Garcinone B, a xanthone derivative naturally isolated from the pericarp of Mangosteen, serves as a potent inhibitor of ACE2 and Mpro, and is utilized in COVID-19 research [1].
    • Inquiry Price
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  • L-Isoleucyl-L-arginine
    T8009655715-01-0
    L-Isoleucyl-L-arginine, a dipeptide composed of L-isoleucine and L-arginine, acts as a potent angiotensin-converting enzyme (ACE) inhibitor and is utilized in hypertension research [1].
    • Inquiry Price
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  • Ovalbumin (154-159)
    T800991370698-94-4
    Ovalbumin (154-159), a peptide fragment derived from ovalbumin, acts as a potent inhibitor of the angiotensin-converting enzyme (ACE) and is utilized in hypertension research [1] [2].
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  • Rentiapril racemate
    T1673172679-47-1
    Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril.Rentiapril racemate has anti-inflammatory activity and may be used in glaucoma research.
    • $117
    Backorder
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  • Ovotransferrin (328-332)
    T801001226776-54-0
    Ovotransferrin (328-332), with an IC50 of 20 μM, exhibits protective activity against hypertension by inhibiting the Angiotensin-Converting Enzyme (ACE) and also displays anti-Cholinesterase (ChE) activity, suggesting a potential role in the treatment of Alzheimer's disease [1] [2].
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  • Isocrenatoside
    T79958221895-09-6
    Isocrenatoside (compound 6), a cyclic octapeptide derived from the ethanolic extract of Microtoena prainiana stems, functions as an angiotensin-converting enzyme (ACE) inhibitor. Research demonstrates that at a concentration of 1 mg/mL, Isocrenatoside achieves an inhibitory efficiency of 99.3% [1].
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  • Temocaprilat
    T20689110221-53-9
    Temocaprilat (RS5139) is an Angiotensin-converting Enzyme (ACE) inhibitor. Temocaprilat is effectively excreted in bile via cMOAT that is deficient in EHBR and that many of other ACE inhibitors have low affinity for cMOAT.
    • $198
    In Stock
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  • Trandolapril
    T532987679-37-6
    Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.
    • $39
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  • Vicenin-1
    TN229535927-38-9
    Vicenin-1 (Vicenin -1) is a flavonoid glycoside isolated from the seeds of the leguminous plant fenugreek with potent anti-inflammatory and antioxidant activity, inhibiting angiotensin-converting enzyme (ACE).
    • $149
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