thioredoxin

Thioredoxin TRX Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.7 kDa and the accession number is P10639.

Expression system: E. coli
Length: 1-105, Full Length
Activity: Enzyme activity

Expression system: E. coli
Length: 1-105, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 60-166, Full Length
Activity: Enzyme activity

Expression system: E. coli
Length: 2-109, Full Length of Mature Protein
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 66-266, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 42-354, Partial
Activity: Not Tested

Expression system: E. coli
Length: 63-256, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 26-269, Partial
Activity: Not Tested

Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. The PDIA6 expressed in platelets, its functions as a chaperone that inhibits aggregation of misfolded proteins. PDIA6 is part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1. PDIA6 also plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.

Expression system: E. coli
Length: 63-256, Partial
Activity: Not Tested

Expression system: E. coli
Length: 125-296, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1-317, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-149, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-123, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-168, Full Length
Activity: Not Tested

Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors. TXNDC12 is widely expressed in many tissues and contains one thioredoxin domain.

TXNDC15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.96 kDa and the accession number is NP_078991.3.

DIM1, also known as TXNL4A, is a member of the Dim protein family. The Dim protein family is composed of two classes, DIM1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4 U6.U5-tri-snRNP. Despite their biological and structural similarities, DIM1 and Dim2 proteins differ in many aspects. DIM1 bears distinctive structural motifs responsible for its interaction with other spliceosome components. Dim2 forms homodimers and contains specific domains required for its interactions with partners. This originality suggests that although both proteins are involved in pre-mRNA splicing, they are likely to be involved in different biological pathways. DIM1 interacts with HNRPF, HNRPH2, NEDD9 HEF1 and PQBP1 NPW38. It plays an essential role in pre-mRNA splicing.

Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA ahpC family of peroxiredoxins. PRDX5 is a widely expressed mitochondrial antioxidant enzyme that reduces hydrogen peroxide, alkyl hydroperoxides, and peroxynitrite. In human cells, this enzyme is present in the cytosol, mitochondria, peroxisomes, and nucleus.

Expression system: HEK293 Cells
Length: 26-273, Full Length of Mature Protein
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 2-199, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-324, Full Length of Isoform 2
Activity: Not Tested

Expression system: E. coli
Length: 1-391, Full Length
Activity: Not Tested