m14

RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.

Anti-IGFBP2 Antibody (M14) is a human monoclonal antibody inhibitor that binds with high affinity to IGFBP2 and prevents its interaction with IGF1. Additionally, Anti-IGFBP2 Antibody (M14) can inhibit the recruitment of human endothelial cells, thereby obstructing tumor progression in human metastatic cancers.

RBM14C12 is a compound known for its cell signaling activity. It plays a crucial role in researching lipid metabolism and cell membrane structure. Additionally, RBM14C12 can be utilized in the development of novel compounds aimed at modulating the biological mechanisms associated with lipid-related diseases.

DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.

BDM14471 is a selective inhibitor of hydroxamate PfAM1.

GEM144 is a potent, orally active dual inhibitor of DNA polymerase α (POLA1) and HDAC 11. GEM144 induces p53 acetylation, activates p21, blocks the cell cycle in G1/S phase and induces apoptosis.

NCATS-SM1440 is a Lactate Dehydrogenase Inhibitor with Optimized Cell Activity and Pharmacokinetic Properties.

HlyU inhibitor CM14 (1025E12) is a useful organic compound for research related to life sciences. The catalog number is T8791 and the CAS number is 588678-13-1.

AM14 is a human monoclonal antibody with the unique ability to bind pre-fusion F epitopes (PreF) and recognize the quality of trimer-specific epitopes.

M145724 ((3Z,6E)-1-N-Methylalbonoursin) is a metabolite that can be extracted from Streptomyces albus.

ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme). It inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361 melanoma cells (EC50s = 41.8 and 67.7 μM, respectively).