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Anti-MAPK14 Monoclonal Antibody (3D611)
(Synonyms: SAPK2A, RK, PRKM15, PRKM14, p38ALPHA, p38, Mxi2, EXIP, CSPB1, CSBP2, CSBP1, CSBP) Copy Product Info
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Synonyms: SAPK2A, RK, PRKM15, PRKM14, p38ALPHA, p38, Mxi2, EXIP, CSPB1, CSBP2, CSBP1, CSBP
Catalog No. TMAT-1360 Copy Product Info
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Anti-MAPK14 Monoclonal Antibody (3D611) is a Mouse antibody targeting MAPK14. Anti-MAPK14 Monoclonal Antibody (3D611) can be used in WB,IHC,IF,FCM.
Anti-MAPK14 Monoclonal Antibody
(3D611)
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| Description | Anti-MAPK14 Monoclonal Antibody (3D611) is a Mouse antibody targeting MAPK14. Anti-MAPK14 Monoclonal Antibody (3D611) can be used in WB,IHC,IF,FCM. |
| Synonyms | SAPK2A, RK, PRKM15, PRKM14, p38ALPHA, p38, Mxi2, EXIP, CSPB1, CSBP2, CSBP1, CSBP |
| Ig Type | IgG1 |
| Clone | 3D611 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/50-1/200; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MAPK14 (AA: 299-360) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MAPK14 |
| Gene ID | |
| Protein Name | Mitogen-activated protein kinase 14 |
| Uniprot ID |
| Molecular Weight | Theoretical: 41.3 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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