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  • Liver X Receptor
    (31)
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Results for "

liver x receptor

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    57
    TargetMol | Inhibitors_Agonists
  • Natural Products
    14
    TargetMol | Natural_Products
  • Recombinant Protein
    5
    TargetMol | Recombinant_Protein
  • Antibody Products
    1
    TargetMol | Antibody_Products
GW3965 hydrochloride
GW3965 HCl
T6310405911-17-3
GW3965 hydrochloride (GW3965 HCl) is an effective and specific LXR agonist for hLXRα β (EC50: 190 30 nM).
  • $35
In Stock
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TargetMol | Inhibitor Hot
GW6340
GW-6340, GW 6340
T77337405910-78-3In house
GW6340 is a selective LXR agonist with potential anticancer activity that promotes macrophage reverse cholesterol transport (mRCT) and can be used to study atherosclerosis.
  • $34 TargetMol
In Stock
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GAC0003A4
GAC0001E5
T68316929492-71-7
GAC0003A4 is a potent LXR inverse agonist with antitumor activity that inhibits the transcription of LXR proteins.GAC0003A4 degrades LXRβ proteins and inhibits the proliferation of PDAC cells in a dose-dependent manner.GAC0003A4 has been used in the study of advanced pancreatic cancers and other recalcitrant malignancies.
  • $67
In Stock
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24-Hydroxycholesterol
Cholest-5-ene-3beta,24-diol
T1008630271-38-6
24-Hydroxycholesterol (Cholest-5-ene-3beta,24-diol) is an oxysterol compound that is an activator of the n-methyl-d-aspartate receptor (NMDA) and the transcription factor LXR, which has been used in the study of cardiogenesis and pancreatic cancer.
  • $129
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GSK2033
T154271221277-90-2
GSK2033 is an antagonist of LXR (pIC50s: 7 and 7.4 for LXRα or LXRβ, respectively).
  • $44
In Stock
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SR9243
T18011613028-81-1
SR9243, an LXR inverse agonist, can induce LXR-corepressor interaction; shows anticancer activity and selectively targets the lipogenesis and Warburg effect.
  • $32
In Stock
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BMS-779788
XL-652, XL652, XL 652, EXEL04286652, BMS-788
T3970918348-67-1
BMS-779788 (XL-652) is an LXRα/β partial agonist (IC50: 68/14 nM).
  • $41
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DMHCA
T4089879066-03-8
DMHCA is a selective LXR agonist with anti-inflammatory activity, which induces ABCA1 expression and upregulates FASN and SREBP-1alpha gene expression.
  • $29
In Stock
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Larsucosterol trimethylamine
DV-928 trimethylamine, DUR-928 trimethylamine
T74147
Larsucosterol trimethylamine (DUR-928 trimethylamine) is a potent liver X receptor (LXR) antagonist that modulates endogenous epigenetics, reduces lipid accumulation in hepatocytes, attenuates lipopolysaccharide (LPS) and TNFα-induced inflammatory responses in macrophages, and alleviates LPS- and acetaminophen (ATMP)-induced multi-organ damage.
  • $192
In Stock
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Iristectorigenin B
Iristectrigenin B
TN235986849-77-6
Iristectorigenin B (Iristectrigenin B) is a potent hepatic X-receptor (LXR) modulator and a small molecule compound isolated from *Belamcanda chinensis*. It promotes the expression of ABCA264 and ABCG7 in macrophage RAW 1.1 cells.
  • $56
In Stock
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27-Hydroxycholesterol
27-OHC, (25R)-26-Hydroxycholesterol
TQ027420380-11-4
27-Hydroxycholesterol (25(R)-27-hydroxy Cholesterol) is a selective modulator of estrogen receptor and an agonist of the liver X receptor.
  • $47
In Stock
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BE1218
T638962893967-40-1
BE1218 is a liver X receptor (LXR) inverse agonist, active on LXRα and LXRβ, with IC50 values of 9 nM and 7 nM, respectively.
  • $41
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24(S)-hydroxy Cholesterol
Cerebrosterol, 24S-OHC, 24S-HC
T21562474-73-7
24(S)-hydroxy Cholesterol (24S-OHC) is the terminal product of the cholesterol elimination pathway in neural tissues. It is an LXR agonist and a selective positive allosteric modulator of NMDARs. It can serve as a biomarker for NPD, induce cognitive decline in mice, and is useful for studying neurological diseases.
    Inquiry
    AN0128
    ONT-0001, ONT0001, CRM-0005, CRM0005, AN 0128
    T26624872044-70-7
    AN0128 (CRM-0005) is an anti-inflammatory boron-containing antibacterial agent that inhibits S. aureus, S. epidermidis, P. acnes, B. subtilis, and suppresses pro-inflammatory cytokine production in macrophage cell lines by inhibiting the p38 MAP kinase signaling pathway. It can be used in dermatological research.
    • $37
    In Stock
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    Larsucosterol Ammonium salt
    DUR-928 Ammonium salt, DUR928 Ammonium salt
    T41015L2655654-16-1
    Larsucosterol ammonium salt is the salt form of Larsucosterol (DUR-928) and a derivative of 25HC3S.Larsucosterol is a DNA methyltransferase inhibitor (DNMT), a potent hepatic X-receptor (LXR) antagonist, an endogenous oxysterol sulfate, and an epigenetic modulator, regulate lipid metabolism, reduce inflammation and treat liver disease.
    • $335
    In Stock
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    (20S)-Protopanaxatriol
    20(S)-APPT, g-PPT
    T281034080-08-5
    (20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid receptor.
    • $32
    In Stock
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    T0901317
    T6690293754-55-9
    T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor κB (NF κB).
    • $32
    In Stock
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    XL041
    BMS-852927
    T146791256918-39-4
    XL041 (BMS-852927) is an agonist selective for LXRβ.
    • Inquiry Price
    8-10 weeks
    Size
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    Rovazolac
    ALX-101
    T167921454288-88-0
    Rovazolac (ALX-101) is a liver x receptor (LXR) modulator used in the study of immune system disorders and atopic dermatitis.
    • $74
    In Stock
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    SR9238
    T169301416153-62-2
    SR9238 is a synthetic agonist of liver X receptor inverse (IC50s: 214 nM and 43 nM for LXRα and LXRβ, respectively).
    • $41
    In Stock
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    LXR-623
    LXR623, WAY 252623
    T1783875787-07-8
    LXR-623 (WAY 252623) is an orally bioavailable and highly specifical synthetic modulator of LXR.
    • $47
    In Stock
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    TargetMol | Inhibitor Sale
    GSK3987
    T27478264206-85-1
    GSK3987 is an LXR ligand. GSK3987 recruits the steroid receptor coactivator-1 to human LXRalpha and LXRbeta with EC50s of 40 nM.
    • $97
    In Stock
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    Saikosaponin A
    T276820736-09-8
    Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropathic pain in CCI rats by inhibiting the activation of p38 MAPK and NF-κB signaling pathways in spinal cord. It can inhibit NMDA receptor current and persistent sodium current, and inhibit the TNF-α level, the IL-1β production, and cysteine-aspartic acid protease (caspase)-1 activity.
    • $30
    In Stock
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    RGX-104 hydrochloride
    SB742881, RGX-104 HCl
    T5128610318-03-1
    RGX-104 hydrochloride (SB742881) is a liver X receptor (LXR) agonist with potential immunomodulating and antineoplastic activities. It modulates innate immunity via transcriptional activation of the ApoE gene.
    • $35
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