leu 2

Enkephalin-leu, ala(2)-ser(6)- is an active compound at the delta (non-complexed) opioid receptor.

(H-Tyr-Ile-Asn-Leu-Cys-Thr-Arg-Nva-Arg-Tyr-NH2)2 trifluoroacetate is a useful organic compound for research related to life sciences and the catalog number is T64688.

(D-Ser2)-Leu-Enkephalin-Thr is a delta selective agent of opioid receptor and shows analgesic effects.

RVN71275, or 2-Furoyl-l-leucylglycinamide, is a highly effective dopamine D2 modulator.

Levitide is a neurohormone-like peptide which is from the skin of Xenopus laevis.

Glycoprotein B is a peptide with the sequence H2N-Ser-Ser-Ile-Glu-Phe-Ala-Arg-Leu-OH, MW= 922.04. glycoprotein B is a viral glycoprotein that is involved in the viral cell entry of Herpes simplex virus. The herpesvirus glycoprotein B is the most highly c

Mca-Pro-Leu-NH2 is a peptide compound and a substrate for matrix protease assays.

Antiflammin P2 is a nonapeptide fragment of lipocortin I which has no phospholipase A2 inhibitory and anti-inflammatory activity.

Deltakephalin is a synthetic, potent specific opiate delta receptors agonist.

Daaccal can be used for relevant research in the life sciences. Its product number is T31173 and CAS number is 103614-06-8.

furylacryloylglycyl leucinamide is a bioactive chemical.

The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain.

SCH-42354 is a potent, orally active inhibitor of neutral endopeptidase (NEP), serving as the active form of the prodrug SCH-42495. By inhibiting NEP hydrolysis, SCH-42354 enhances the activity of atrial natriuretic peptide (ANP) and prevents the hydrolysis of leu-enkephalin and ANF with IC50 values of 8.3 nM and 10.0 nM, respectively. Furthermore, SCH-42354 exhibits antihypertensive activity [1] [2].

D-Leu-Ty hydrate ((S)-2-((R)-2-Amino-4-methylpentanamido)-3-(4-hydroxyphenyl)propanoic acid hydrate) is a tyrosine derivative commonly used in drug synthesis and biochemistry research.

Fmoc-D-Leu-OH, catalog number T67556 and CAS number 114360-54-2, is a valuable organic compound for life sciences research.

N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor (IC50 = 75 μM) that effectively inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat [1].

Hippuryl-His-Leu-OH serves as a substrate to measure angiotensin I converting enzyme activity. Upon its cleavage, the resultant His-Leu moiety reacts with o-phthaldialdehyde or Fluorescamine, facilitating fluorescence detection [1] [2] [3].

H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that serves as a substrate for the enzymes cathepsin D, pepsin, and pepsinogen, with potential applications in biochemical analysis [1] [2].

Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM and also serves as an inhibitor of NF-κB nuclear translocation, as documented in references [1] [2].

TNO211 is a bioactive peptide that functions as a highly soluble fluorogenic substrate for select Matrix Metalloproteinases (MMPs)—specifically MMP-2, 8, 12, 13, and 14. Incorporating a cleavable Gly-Leu bond and an EDANS DABCYL fluorophore quencher pair, TNO211 enables sensitive detection of MMP activity through fluorescence assays, with an absorption emission profile at 340 490 nm. It is particularly effective in analyzing MMPs in culture media from endothelial cells as well as untreated synovial fluid from patients, highlighting its utility in investigations of MMP-associated cellular behaviors, including proliferation, migration (adhesion dispersion), differentiation, angiogenesis, apoptosis, and host defense.

Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) acts as a cysteine protease inhibitor and has demonstrated efficacy in blocking SARS infection, while also providing protection to mice when challenged with T. crassiceps [1] [2].

Semzuvolimab, a murine IgG1κ antibody, targets the p55 T-cell surface antigen T4 Leu-3 (CD4). It has demonstrated capabilities to neutralize HIV infection and may inhibit HIV in patients on stable highly active antiretroviral therapy (HAART) [1] [2].

The sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK, specifically cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2), which interacts with human IIA phospholipase A2 (hGIIA) to impede its ester bond hydrolyzing function. As part of the esterase superfamily, sPLA2 enzymatically cleaves the sn-2 ester bond in glycerophospholipids, releasing arachidonic acid and lysophospholipids[1].

Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biologically active peptide. Structure-activity studies of the thrombin receptor-tethered ligand SFLLRNP highlighted the pivotal role of the Phe-2-phenyl group in receptor recognition, while substitution with para-fluorophenylalanine [(p-F)Phe] increased its activity.