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KSI-3716 is a c-Myc inhibitor used as a bladder chemotherapy agent. It blocks the formation of the c-MYC/MAX complex with the target gene promoter and induces cell cycle arrest and apoptosis. It can be used for bladder cancer research.

Perfluorinated SAHA is an HDAC inhibitor for use in cancer treatment regimens, with demonstrated greater antiproliferative properties than SAHA . PFSAHA has also been shown to have higher selectivity for PA3774, an HDAC-like enzyme from P. aeruginosa, as well as other HDACs, which may prove beneficial for developing novel chemotherapeutic treatments for cancer.

KSI-6666 is an orally effective competitive antagonist of sphingosine 1-phosphate receptor 1 (S1PR1), with an IC50 value of 6.4 nM. It exhibits anti-inflammatory activity in models of autoimmune encephalomyelitis and T-cell transfer-induced colitis.

PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 μM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 μM, respectively). PKSI-527 reduces bradykinin generation induced by kaolin and λ-carrageenan ex vivo in human plasma. It also prolongs partial thromboplastin and euglobulin clot lysis times. In vivo, PKSI-527 (300 mg/kg per day) reduces hyperplasia, pannus formation, and infiltration of inflammatory cells in the tarsal joint of mice with collagen-induced arthritis.

The compound AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG facilitates bone ossification and has potential applications in the study of conditions associated with osteogenic insufficiency or diminished bone mineral density (BMD), including osteoporosis [1].

Pinobanksin is a natural flavonoid that induces apoptosis in B-cell lymphoma cell lines and SH-SY5Y cells. It is a potent antioxidant that inhibits the peroxidation of low-density lipoprotein (LDL) and is able to occupy the catalytic center of xanthine oxidase (XO) and thus inhibit it. Pinobanksin also exhibits antimicrobial, anti-inflammatory, antiparasitic, anti-mutagenic, anti-proliferative, and anti-angiogenic effects.

10-Hydroxydihydroperaksine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN2568 and the CAS number is 451478-47-0. 10-Hydroxydihydroperaksine can be used as a reference standard.

3,7-O-Diacetylpinobanksin is a natural product of Pinus, Pinaceae. The catalog number is TN2910 and the CAS number is 103553-98-6. 3,7-O-Diacetylpinobanksin can be used as a reference standard.

Pinobanksin 3-acetate (3-O-Acetylpinobanksin), a flavonoid derivative, is a strong antioxidant found in sunflowers and honey that inhibits LDL peroxidation.

Dihydroperaksine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN3860 and the CAS number is 16100-84-8. Dihydroperaksine can be used as a reference standard.

Pinobanksin 3-O-propanoate is a natiral product from forest trees.

Pinobanksin 5-methyl ether can induce detoxification genes.

Pinobanksin 3-(2-methyl)butyrate is a Pinobanksin derivative. pinobanksin is a apoptosis inducer that can induce apoptosis of F6 cells.

Peraksine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN6030 and the CAS number is 15527-80-7. Peraksine can be used as a reference standard.

KS I is a gonadotropin antagonist and is a cyclolignan isolated from extracts of Lycopus and Lithosperum after oxidation with caffeic acid.

HMR 1556 is a chromanol derivative and is an IKs blocker (IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively).

PI5P4Ks-IN-2 is an inhibitor of the phosphatidylinositol 5-phosphate 4-kinase PI5P4Kγ. Targeting the PI5P4K isoforms, PI5P4Ks-IN-2 inhibited PI5P4Kα, PI5P4Kβ, PI5P4Kγ, and PI5P4Kγ+, with IC50 values of <4.3, <4.6, 6.2, and 0.32, respectively.

DYRKs-IN-1 has antitumor activity. DYRKs-IN-1 is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 9 nM and 5 nM for DYRK1B and DYRK1A, respectively.

DYRKs-IN-2 has antitumor activity. DYRKs-IN-2 is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively.

Diazepinomicin is a secondary metabolite produced by Micromonospora sp. It inhibits the EGF-induced Ras-ERK MAPK signaling pathway and induces apoptosis. Diazepinomicin also is an anti-tumor agent for K-Ras mutant models.

Bitriben is an agent with the anthelmintic effect.

TNKS-IN-3 (Compound 6) is a TNKS2 inhibitor with a Ki of 8.5 nM. It demonstrates strong activity with an IC50 of 71 nM, effectively inhibiting the WNT/β-catenin signaling pathway, and is useful for research in cancer and fibrosis.

TNKS-IN-41 highly potent and selective inhibitor of tankyrase.

Gentamicin (Centicin) is a broad-spectrum aminoglycoside antibiotic with antibacterial activity, inhibiting the growth of Gram-positive and Gram-negative bacteria, and can be used to study ocular infections.